Basic Information
ID: ALA1176303
Type: Functional
Description: Smoke cessation activity in sc dosed ICR mouse assessed as inhibition of nicotine-induced antinociception administered 15 mins before nicotine challenge measured after 5 mins of nicotine infusion by tail-flick assay
Organism: Mus musculus
Strain: ICR
Tissue: Tail
Activity Charts
Bioactivity
Activity Types for Assay ALA1176303
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 239.75 | 3.30 | 3.30 |
| 283.80 | 3.05 | 3.05 |
| 269.77 | 2.61 | 2.61 |
| 269.77 | 2.61 | 2.61 |
| 222.29 | 1.01 | 1.01 |
| 222.29 | 1.01 | 1.01 |
| 255.74 | 2.27 | 2.27 |
| 255.75 | 2.27 | 2.27 |
| 221.30 | 1.62 | 1.62 |
| 239.29 | 1.76 | 1.76 |
| 300.20 | 2.38 | 2.38 |
| 235.33 | 1.93 | 1.93 |
| 251.33 | 1.63 | 1.63 |
| 266.30 | 1.53 | 1.53 |
| 239.29 | 1.76 | 1.76 |
| 255.75 | 2.27 | 2.27 |
| 235.33 | 1.93 | 1.93 |
| 251.33 | 1.63 | 1.63 |
| 257.28 | 1.90 | 1.90 |
| 290.19 | 2.93 | 2.93 |
| 257.28 | 1.90 | 1.90 |
| 290.19 | 2.93 | 2.93 |
| 297.40 | 3.29 | 3.29 |
| 347.46 | 4.44 | 4.44 |
| 347.46 | 4.44 | 4.44 |
| 269.77 | 2.66 | 2.66 |