Assay Report Card

Basic Information

ID: ALA1177272

Type: Binding

Description: Inhibition of Escherichia coli FimH-mediated hemagglutinination of guinea pig red blood cells assessed as drug level required for > 90% inhibition of hemagglutinination

Organism: Escherichia coli

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
332.350.530.53
360.360.100.10
390.390.320.32
390.390.320.32
333.34-0.07-0.07
333.34-0.07-0.07
376.360.230.23
357.360.400.40
357.360.400.40
357.360.400.40
362.380.020.02
362.380.020.02
362.380.020.02
348.350.240.24
348.350.240.24
348.350.240.24
362.380.540.54
362.380.540.54
425.46-0.10-0.10
425.46-0.10-0.10
425.46-0.56-0.56
425.46-0.56-0.56
377.350.440.44
377.350.440.44
375.38-0.37-0.37
375.38-0.37-0.37
400.351.551.55
400.351.551.55
350.340.670.67
448.420.110.11
446.46-0.75-0.75
420.37-0.07-0.07
609.581.301.30
820.85-0.45-0.45
864.90-0.43-0.43
236.26-1.40-1.40
278.35-0.23-0.23
313.26-1.70-1.70
370.38-0.13-0.13
370.38-0.13-0.13
332.350.530.53
390.390.320.32
314.29-1.21-1.21
328.32-1.42-1.42
372.33-1.56-1.56
338.31-0.72-0.72
312.27-1.67-1.67
306.310.020.02
301.25-1.23-1.23
301.25-1.23-1.23
271.27-1.55-1.55
270.28-0.83-0.83
389.40-0.11-0.11
389.400.490.49
256.25-1.13-1.13
270.28-0.83-0.83
290.70-0.48-0.48
290.70-0.48-0.48
290.70-0.48-0.48
314.29-1.35-1.35
314.29-1.35-1.35
300.26-1.44-1.44
281.26-1.26-1.26
281.26-1.26-1.26
286.28-1.13-1.13
313.31-1.18-1.18
313.31-1.18-1.18
281.26-1.26-1.26
313.31-1.18-1.18
299.28-2.04-2.04
299.28-2.04-2.04