Basic Information
ID: ALA1212595
Type: Functional
Description: Antagonist activity at human Smo receptor in HEPM cells assessed as inhibition of Gli expression after 24 hrs by quantigene assay
Organism: Homo sapiens
Cell type: HEPM
Activity Charts
Bioactivity
Activity Types for Assay ALA1212595
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.48 | 4.26 | 4.26 |
| 408.51 | 4.65 | 4.65 |
| 408.51 | 4.65 | 4.65 |
| 463.37 | 5.57 | 5.57 |
| 438.53 | 4.14 | 4.14 |
| 451.57 | 4.71 | 4.71 |
| 476.50 | 5.67 | 5.67 |
| 426.50 | 4.79 | 4.79 |
| 451.53 | 3.75 | 3.75 |
| 493.61 | 4.48 | 4.48 |
| 452.51 | 4.35 | 4.35 |
| 466.54 | 4.57 | 4.57 |
| 465.56 | 3.68 | 3.68 |
| 409.49 | 4.04 | 4.04 |
| 409.49 | 4.04 | 4.04 |
| 409.49 | 4.04 | 4.04 |
| 397.48 | 3.77 | 3.77 |
| 447.54 | 4.92 | 4.92 |
| 399.45 | 3.64 | 3.64 |
| 398.47 | 3.17 | 3.17 |
| 412.50 | 3.33 | 3.33 |
| 410.48 | 3.44 | 3.44 |
| 409.49 | 4.04 | 4.04 |
| 409.49 | 4.04 | 4.04 |
| 409.49 | 4.04 | 4.04 |
| 409.49 | 4.04 | 4.04 |
| 477.49 | 5.06 | 5.06 |