Basic Information
ID: ALA1219573
Type: Functional
Description: Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assay
Format: BAO_0000219
Cell type: Huh-7
Target: Mineralocorticoid receptor(ALA1994)
Document: ALA1212896
Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1219573
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.50 | 3.12 | 3.12 |
| 388.42 | 3.34 | 3.34 |
| 362.83 | 4.58 | 4.58 |
| 377.87 | 4.09 | 4.09 |
| 361.41 | 3.58 | 3.58 |
| 411.42 | 4.45 | 4.45 |
| 357.45 | 3.74 | 3.74 |
| 373.45 | 3.44 | 3.44 |
| 357.45 | 3.74 | 3.74 |
| 368.43 | 3.31 | 3.31 |
| 373.45 | 3.44 | 3.44 |
| 377.87 | 4.09 | 4.09 |
| 411.42 | 4.45 | 4.45 |
| 359.42 | 3.14 | 3.14 |
| 361.41 | 3.58 | 3.58 |
| 411.42 | 4.45 | 4.45 |
| 359.42 | 3.14 | 3.14 |
| 361.41 | 3.58 | 3.58 |
| 357.45 | 3.74 | 3.74 |
| 373.45 | 3.44 | 3.44 |
| 377.87 | 4.09 | 4.09 |
| 395.86 | 4.23 | 4.23 |
| 395.86 | 4.23 | 4.23 |
| 328.39 | 3.93 | 3.93 |
| 342.41 | 4.10 | 4.10 |
| 346.38 | 4.06 | 4.06 |
| 374.43 | 4.80 | 4.80 |
| 404.46 | 4.42 | 4.42 |
| 320.75 | 3.41 | 3.41 |
| 302.76 | 3.27 | 3.27 |
| 316.79 | 3.66 | 3.66 |
| 330.82 | 4.05 | 4.05 |
| 330.82 | 3.91 | 3.91 |
| 344.84 | 4.44 | 4.44 |
| 332.79 | 2.90 | 2.90 |
| 378.86 | 4.80 | 4.80 |
| 413.30 | 5.45 | 5.45 |
| 378.86 | 4.49 | 4.49 |
| 296.37 | 3.40 | 3.40 |
| 348.81 | 4.19 | 4.19 |
| 374.72 | 3.95 | 3.95 |
| 388.75 | 4.30 | 4.30 |
| 386.81 | 3.29 | 3.29 |
| 386.81 | 3.29 | 3.29 |
| 387.80 | 2.68 | 2.68 |
| 388.79 | 2.08 | 2.08 |
| 388.79 | 2.08 | 2.08 |