ID: ALA1219905
Type: Binding
Description: Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assay
Cell type: MDCK
Bioactivity
Activity Types for Assay ALA1219905
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
366.38 | 0.97 | 0.97 |
375.47 | 6.06 | 6.06 |
240.24 | 0.45 | 0.45 |
240.24 | 0.45 | 0.45 |
187.16 | 0.85 | 0.85 |
270.27 | 0.54 | 0.54 |
302.31 | 1.81 | 1.81 |
302.31 | 1.81 | 1.81 |
205.17 | 0.07 | 0.07 |
187.16 | 0.85 | 0.85 |
177.16 | 0.56 | 0.56 |
205.17 | 0.07 | 0.07 |
177.16 | 0.56 | 0.56 |
192.17 | 0.98 | 0.98 |
176.18 | 1.28 | 1.28 |
298.32 | 1.32 | 1.32 |
298.32 | 1.32 | 1.32 |
238.25 | 2.64 | 2.64 |
176.18 | 1.28 | 1.28 |
192.17 | 0.98 | 0.98 |
207.15 | 0.88 | 0.88 |
207.15 | 0.88 | 0.88 |
241.23 | -0.38 | -0.38 |
241.23 | -0.38 | -0.38 |
269.24 | -0.76 | -0.76 |
269.24 | -0.76 | -0.76 |
251.22 | 0.01 | 0.01 |
251.22 | 0.01 | 0.01 |
326.37 | 2.10 | 2.10 |
354.43 | 2.88 | 2.88 |
382.48 | 3.66 | 3.66 |
284.29 | 0.93 | 0.93 |
318.31 | 1.93 | 1.93 |
282.32 | 2.08 | 2.08 |
310.38 | 2.86 | 2.86 |