Assay Report Card

Basic Information

ID: ALA1219905

Type: Binding

Description: Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assay

Cell type: MDCK

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
366.380.970.97
375.476.066.06
240.240.450.45
240.240.450.45
187.160.850.85
270.270.540.54
302.311.811.81
302.311.811.81
205.170.070.07
187.160.850.85
177.160.560.56
205.170.070.07
177.160.560.56
192.170.980.98
176.181.281.28
298.321.321.32
298.321.321.32
238.252.642.64
176.181.281.28
192.170.980.98
207.150.880.88
207.150.880.88
241.23-0.38-0.38
241.23-0.38-0.38
269.24-0.76-0.76
269.24-0.76-0.76
251.220.010.01
251.220.010.01
326.372.102.10
354.432.882.88
382.483.663.66
284.290.930.93
318.311.931.93
282.322.082.08
310.382.862.86