Basic Information
ID: ALA1219914
Type: Functional
Description: Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltage-clamp electrophysiology
Organism: Rattus norvegicus
Cell type: Oocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA1219914
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.39 | 3.96 | 3.96 |
| 443.42 | 4.17 | 4.17 |
| 406.18 | 3.00 | 3.00 |
| 494.29 | 4.86 | 4.86 |
| 382.42 | 4.56 | 4.56 |
| 384.44 | 4.18 | 4.18 |
| 413.39 | 4.16 | 4.16 |
| 413.39 | 4.16 | 4.16 |
| 413.39 | 4.16 | 4.16 |
| 413.39 | 4.16 | 4.16 |
| 418.45 | 5.41 | 5.41 |
| 448.48 | 5.42 | 5.42 |
| 418.45 | 5.41 | 5.41 |
| 453.50 | 4.09 | 4.09 |
| 399.41 | 4.47 | 4.47 |
| 399.41 | 4.47 | 4.47 |
| 399.41 | 4.47 | 4.47 |
| 399.41 | 4.47 | 4.47 |
| 426.43 | 4.03 | 4.03 |
| 325.37 | 3.95 | 3.95 |
| 451.27 | 4.56 | 4.56 |
| 481.29 | 4.56 | 4.56 |
| 481.29 | 4.56 | 4.56 |
| 399.41 | 4.47 | 4.47 |
| 399.41 | 4.47 | 4.47 |
| 399.41 | 4.47 | 4.47 |
| 399.41 | 4.47 | 4.47 |
| 481.29 | 4.56 | 4.56 |
| 465.29 | 4.86 | 4.86 |
| 465.29 | 4.86 | 4.86 |
| 465.29 | 4.86 | 4.86 |
| 496.26 | 4.46 | 4.46 |
| 368.39 | 4.25 | 4.25 |
| 398.42 | 4.26 | 4.26 |
| 398.42 | 4.26 | 4.26 |
| 398.42 | 4.26 | 4.26 |
| 496.26 | 4.46 | 4.46 |
| 496.26 | 4.46 | 4.46 |
| 495.28 | 4.25 | 4.25 |
| 495.28 | 4.25 | 4.25 |
| 369.38 | 4.46 | 4.46 |
| 436.39 | 5.27 | 5.27 |
| 436.39 | 5.27 | 5.27 |
| 436.39 | 5.27 | 5.27 |
| 384.39 | 3.96 | 3.96 |
| 399.41 | 4.47 | 4.47 |
| 384.39 | 3.96 | 3.96 |
| 382.42 | 4.56 | 4.56 |
| 382.42 | 4.56 | 4.56 |
| 382.42 | 4.56 | 4.56 |
| 447.83 | 4.82 | 4.82 |
| 447.83 | 4.82 | 4.82 |
| 447.83 | 4.82 | 4.82 |
| 447.83 | 4.82 | 4.82 |
| 482.28 | 5.47 | 5.47 |
| 482.28 | 5.47 | 5.47 |
| 431.38 | 4.30 | 4.30 |
| 492.29 | 4.93 | 4.93 |
| 539.29 | 4.77 | 4.77 |
| 427.42 | 4.47 | 4.47 |
| 443.42 | 4.17 | 4.17 |
| 458.39 | 4.07 | 4.07 |
| 429.39 | 3.87 | 3.87 |
| 489.49 | 5.83 | 5.83 |
| 463.45 | 5.32 | 5.32 |
| 471.43 | 3.93 | 3.93 |
| 457.40 | 3.89 | 3.89 |
| 455.47 | 5.29 | 5.29 |
| 455.47 | 5.12 | 5.12 |
| 495.52 | 5.89 | 5.89 |
| 515.53 | 6.33 | 6.33 |
| 424.42 | 4.34 | 4.34 |
| 442.43 | 3.57 | 3.57 |
| 457.44 | 4.26 | 4.26 |
| 428.44 | 4.27 | 4.27 |
| 442.43 | 3.96 | 3.96 |
| 456.45 | 4.05 | 4.05 |
| 514.49 | 3.84 | 3.84 |
| 414.49 | 4.98 | 4.98 |
| 393.40 | 4.13 | 4.13 |
| 411.46 | 4.32 | 4.32 |
| 434.40 | 4.86 | 4.86 |
| 424.46 | 4.82 | 4.82 |
| 442.43 | 3.72 | 3.72 |
| 412.40 | 3.95 | 3.95 |
| 539.29 | 4.77 | 4.77 |
| 413.39 | 4.16 | 4.16 |
| 413.39 | 4.16 | 4.16 |
| 413.39 | 4.16 | 4.16 |
| 413.39 | 4.16 | 4.16 |
| 539.29 | 4.77 | 4.77 |
| 539.29 | 4.77 | 4.77 |
| 443.42 | 4.17 | 4.17 |
| 443.42 | 4.17 | 4.17 |