Assay Report Card

Basic Information

ID: ALA1220165

Type: Binding

Description: Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 50 uM by thioflavin T fluorescence assay relative to untreated control

Organism: Saccharomyces cerevisiae

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
329.364.064.06
270.242.582.58
234.342.582.58
305.503.203.20
344.855.385.38
306.280.740.74
326.310.700.70
397.766.526.52
479.533.683.68