Basic Information
ID: ALA1220170
Type: Binding
Description: Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 50 uM in presence of 5 mg/ml BSA by thioflavin T fluorescence assay relative to untreated control
Organism: Saccharomyces cerevisiae
Activity Charts
Bioactivity
Activity Types for Assay ALA1220170
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.36 | 4.06 | 4.06 |
| 270.24 | 2.58 | 2.58 |
| 234.34 | 2.58 | 2.58 |
| 305.50 | 3.20 | 3.20 |
| 344.85 | 5.38 | 5.38 |
| 306.28 | 0.74 | 0.74 |
| 326.31 | 0.70 | 0.70 |
| 397.76 | 6.52 | 6.52 |
| 479.53 | 3.68 | 3.68 |