Basic Information
ID: ALA1220444
Type: Binding
Description: Inhibition of beta lactamase CTX-M assessed as hydrolysis of beta lactam up to 5 mM by spectrometry analysis
Activity Charts
Bioactivity
Activity Types for Assay ALA1220444
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 180.16 | 1.20 | 1.20 |
| 117.10 | -0.79 | -0.79 |
| 145.11 | -1.11 | -1.11 |
| 229.24 | 1.65 | 1.65 |
| 164.16 | 1.49 | 1.49 |
| 200.22 | 0.79 | 0.79 |
| 152.15 | 0.60 | 0.60 |
| 140.09 | 0.34 | 0.34 |
| 152.15 | 1.02 | 1.02 |
| 205.21 | 1.57 | 1.57 |
| 206.20 | 0.59 | 0.59 |
| 232.28 | 1.52 | 1.52 |
| 208.17 | -0.71 | -0.71 |
| 212.16 | 0.55 | 0.55 |
| 165.15 | 0.95 | 0.95 |
| 232.24 | 1.89 | 1.89 |
| 203.20 | 1.16 | 1.16 |
| 205.21 | 0.60 | 0.60 |
| 180.21 | 1.23 | 1.23 |
| 221.21 | 1.30 | 1.30 |
| 249.22 | 1.81 | 1.81 |
| 231.25 | 1.30 | 1.30 |
| 271.27 | 2.62 | 2.62 |
| 304.28 | 3.66 | 3.66 |
| 331.35 | 3.19 | 3.19 |
| 252.25 | 0.79 | 0.79 |
| 252.25 | 1.11 | 1.11 |
| 252.32 | 2.67 | 2.67 |
| 275.31 | 1.34 | 1.34 |
| 291.30 | 1.24 | 1.24 |
| 297.38 | 2.05 | 2.05 |
| 313.38 | 1.96 | 1.96 |
| 258.27 | 2.46 | 2.46 |
| 273.31 | 1.46 | 1.46 |
| 326.30 | 3.02 | 3.02 |
| 331.32 | 2.56 | 2.56 |
| 203.20 | -2.35 | -2.35 |
| 345.37 | 3.56 | 3.56 |
| 293.30 | 1.89 | 1.89 |
| 268.27 | 2.61 | 2.61 |
| 335.34 | 2.11 | 2.11 |
| 253.24 | 2.01 | 2.01 |
| 348.38 | 1.22 | 1.22 |
| 303.25 | 0.84 | 0.84 |
| 297.35 | 3.44 | 3.44 |
| 346.14 | 2.95 | 2.95 |
| 262.26 | -0.31 | -0.31 |
| 250.28 | 0.75 | 0.75 |
| 301.32 | 2.58 | 2.58 |
| 278.29 | 1.58 | 1.58 |
| 266.30 | 3.10 | 3.10 |
| 301.69 | 2.84 | 2.84 |
| 326.40 | 3.81 | 3.81 |
| 343.40 | 4.07 | 4.07 |
| 331.30 | 2.50 | 2.50 |
| 273.29 | 2.78 | 2.78 |
| 283.33 | 2.56 | 2.56 |
| 343.46 | 2.86 | 2.86 |
| 319.36 | 3.42 | 3.42 |
| 131.13 | -1.21 | -1.21 |
| 179.17 | 1.10 | 1.10 |
| 155.11 | 0.19 | 0.19 |
| 156.10 | -1.24 | -1.24 |
| 175.16 | -0.19 | -0.19 |
| 202.19 | 0.06 | 0.06 |
| 225.24 | -0.38 | -0.38 |
| 243.29 | 0.48 | 0.48 |
| 243.27 | 0.95 | 0.95 |
| 176.17 | 1.44 | 1.44 |
| 176.18 | 1.12 | 1.12 |
| 181.19 | 1.18 | 1.18 |
| 238.67 | 1.34 | 1.34 |
| 228.20 | 1.48 | 1.48 |
| 221.24 | 1.50 | 1.50 |
| 169.14 | 0.50 | 0.50 |
| 233.27 | 1.74 | 1.74 |
| 223.16 | 0.51 | 0.51 |
| 197.23 | 0.86 | 0.86 |
| 201.20 | 0.03 | 0.03 |
| 140.09 | 0.07 | 0.07 |
| 223.23 | 1.93 | 1.93 |
| 186.19 | 0.80 | 0.80 |
| 140.10 | -0.53 | -0.53 |
| 238.25 | 2.93 | 2.93 |
| 127.10 | 0.68 | 0.68 |
| 227.65 | 1.54 | 1.54 |
| 208.14 | 1.63 | 1.63 |
| 185.20 | 1.40 | 1.40 |
| 199.23 | 0.87 | 0.87 |
| 183.21 | 1.38 | 1.38 |
| 207.23 | 1.20 | 1.20 |
| 229.26 | 2.27 | 2.27 |
| 221.26 | 0.71 | 0.71 |
| 239.66 | 2.17 | 2.17 |
| 219.24 | 2.01 | 2.01 |
| 204.23 | 1.81 | 1.81 |