Assay Report Card

Basic Information

ID: ALA1220854

Type: Binding

Description: Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization preincubation of seed fibers and compound for 5 mins at 100 uM by thioflavin T fluorescence assay relative to untreated control

Organism: Saccharomyces cerevisiae

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
344.855.385.38
479.533.683.68