Basic Information
ID: ALA1225450
Type: Binding
Description: Inhibition of indoleamine-2,3-dioxygenase in human A431 cells assessed as inhibition of IFN-gamma-stimulated kynurenine production
Organism: Homo sapiens
Cell type: A-431
Activity Charts
Bioactivity
Activity Types for Assay ALA1225450
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 141.60 | 1.80 | 1.80 |
| 144.63 | 2.63 | 2.63 |
| 155.63 | 1.84 | 1.84 |
| 328.61 | 3.05 | 3.05 |
| 186.67 | 2.00 | 2.00 |
| 202.71 | 1.81 | 1.81 |
| 237.16 | 2.47 | 2.47 |
| 237.16 | 2.47 | 2.47 |
| 237.16 | 2.47 | 2.47 |
| 220.70 | 1.95 | 1.95 |
| 326.06 | 2.58 | 2.58 |
| 216.74 | 2.12 | 2.12 |
| 230.76 | 2.38 | 2.38 |
| 289.24 | 2.94 | 2.94 |
| 303.27 | 3.11 | 3.11 |
| 270.71 | 2.83 | 2.83 |
| 232.74 | 1.82 | 1.82 |
| 272.17 | 1.68 | 1.68 |
| 247.71 | 1.72 | 1.72 |
| 246.72 | 1.51 | 1.51 |
| 325.25 | 1.22 | 1.22 |
| 351.27 | 3.04 | 3.04 |
| 316.05 | 3.12 | 3.12 |
| 271.60 | 3.12 | 3.12 |
| 295.63 | 2.51 | 2.51 |
| 295.63 | 2.51 | 2.51 |
| 295.63 | 2.51 | 2.51 |
| 329.21 | 2.78 | 2.78 |
| 356.66 | 2.77 | 2.77 |
| 214.72 | 1.72 | 1.72 |
| 184.63 | 1.51 | 1.51 |
| 142.58 | 1.83 | 1.83 |
| 158.65 | 2.77 | 2.77 |
| 158.65 | 2.77 | 2.77 |
| 124.21 | 2.12 | 2.12 |
| 142.20 | 2.26 | 2.26 |
| 138.24 | 2.42 | 2.42 |
| 154.23 | 2.12 | 2.12 |
| 193.10 | 3.42 | 3.42 |
| 193.10 | 3.42 | 3.42 |
| 192.62 | 1.59 | 1.59 |
| 198.61 | 1.92 | 1.92 |