Antagonist activity at wild type NR1/NR2A receptor expressed in Xenopus oocytes assessed as ratio of residual current induced by agonist in presence o...

Basic Information

ID: ALA1225540

Type: Functional

Description: Antagonist activity at wild type NR1/NR2A receptor expressed in Xenopus oocytes assessed as ratio of residual current induced by agonist in presence of compound to residual current induced by agonist alone at 10 uM by two-electrode voltage-clamp method

Format: BAO_0000219

Cell type: Oocyte

Target:  Glutamate NMDA receptor; GRIN1/GRIN2A(ALA1907604)

Document:  ALA1221329

Antagonist activity at wild type NR1/NR2A receptor expressed in Xenopus oocytes assessed as ratio of residual current induced by agonist in presence of compound to residual current induced by agonist alone at 10 uM by two-electrode voltage-clamp method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
325.453.773.77
329.403.893.89
402.452.822.82
267.321.991.99
451.530.930.93
379.493.183.18
395.274.794.79
301.823.243.24
356.473.043.04
396.863.913.91
316.793.653.65
379.493.183.18
395.482.892.89
363.493.473.47
379.493.183.18
409.513.193.19
317.412.002.00
365.463.183.18
383.453.323.32
399.903.843.84
409.513.503.50
409.513.503.50
443.964.164.16
365.463.183.18