Basic Information
ID: ALA1227168
Type: Binding
Description: Inhibition of gamma-secretase in HEK293 cells co-overexpressing NotchdeltaE assessed as inhibition of notch cleavage at 1 uM by luciferase reporter gene assay relative to DAPT
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1227168
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.40 | 4.30 | 4.30 |
| 409.40 | 4.30 | 4.30 |
| 409.40 | 4.30 | 4.30 |
| 397.37 | 4.43 | 4.43 |
| 381.35 | 3.66 | 3.66 |
| 395.38 | 3.91 | 3.91 |
| 413.37 | 4.31 | 4.31 |
| 421.47 | 5.20 | 5.20 |
| 439.43 | 4.22 | 4.22 |
| 433.50 | 5.07 | 5.07 |