Basic Information
ID: ALA1227178
Type: Binding
Description: Inhibition of gamma-secretase in HEK293 cells co-overexpressing NotchdeltaE assessed as inhibition of notch cleavage by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1227178
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.42 | 5.35 | 5.35 |
| 409.40 | 4.30 | 4.30 |
| 409.40 | 4.30 | 4.30 |
| 407.39 | 4.52 | 4.52 |