Assay Report Card

Basic Information

ID: ALA1243414

Type: Binding

Description: Induction of nuclear translocation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (468-490) at 1 uM exposed for 30 mins at 4 hrs post fertilization by Gal4 dependent luciferase reportre gene assay relative to untreated control

Organism: Bombyx mori

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
352.484.454.45