Assay Report Card

Basic Information

ID: ALA1243422

Type: Binding

Description: Activation of Bombyx mori Ecdysone receptor V454I and Y474E mutant (amino acids 272-606) expressed in AB zebrafish embryos transfected with cytomegalovirus promoter-driven expression construct encoding chimeric transactivator composed of DBD and homodimerization domains of yeast Gal4 (amino acids 1-146) and VP16 activation domain (amino acids (456-490) at 10 uM exposed for 16 hrs by Gal4 dependent luciferase reportre gene assay relative to untreated control

Organism: Bombyx mori

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
352.484.454.45