Assay Report Card

Basic Information

ID: ALA1243965

Type: Binding

Description: Inhibition of recombinant PI3Kalpha by radioactive phosphotransfer assay in presence of 10 uM ATP

Activity Charts

Bioactivity

Activity Types for Assay ALA1243965

IC50

Total(209)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
398.48	3.33	3.33
446.91	4.28	4.28
464.83	5.55	5.55
488.02	3.31	3.31
319.37	3.07	3.07
269.31	2.36	2.36
317.40	3.98	3.98
325.37	2.82	2.82
304.36	3.20	3.20
275.31	2.77	2.77
265.28	1.49	1.49
264.29	2.09	2.09
255.24	1.33	1.33
281.34	2.83	2.83
211.23	1.60	1.60
225.25	1.91	1.91
225.25	1.91	1.91
225.25	1.91	1.91
239.28	2.22	2.22
267.34	2.90	2.90
269.31	2.36	2.36
227.23	1.31	1.31
268.32	2.97	2.97
241.25	1.62	1.62
255.28	1.63	1.63
320.15	2.08	2.08
257.25	1.32	1.32
271.28	1.33	1.33
227.23	1.31	1.31
226.24	1.18	1.18
226.24	1.18	1.18
256.23	1.51	1.51
256.23	1.51	1.51
254.30	2.05	2.05
255.29	1.45	1.45
271.28	2.06	2.06
265.32	2.21	2.21
261.29	2.76	2.76
398.47	4.01	4.01
402.39	3.62	3.62
301.33	2.80	2.80
303.75	3.02	3.02
298.35	2.25	2.25
356.43	2.46	2.46
310.36	2.48	2.48
301.35	3.41	3.41
303.37	3.81	3.81
293.33	3.40	3.40
319.37	3.94	3.94
295.31	2.19	2.19
348.20	3.12	3.12
318.77	1.95	1.95
318.77	1.95	1.95
315.76	3.16	3.16
324.39	2.78	2.78
283.34	2.15	2.15
292.35	2.72	2.72
329.41	4.34	4.34
351.41	4.28	4.28
309.33	1.83	1.83
295.35	2.59	2.59
311.35	2.43	2.43
308.35	2.84	2.84
319.37	2.84	2.84
329.79	3.55	3.55
330.78	1.97	1.97
331.76	2.40	2.40
292.35	2.72	2.72
278.32	2.53	2.53
296.31	2.67	2.67
330.40	3.74	3.74
318.38	3.51	3.51
338.80	3.86	3.86
337.41	3.68	3.68
489.54	4.15	4.15
331.76	2.40	2.40
344.81	2.19	2.19
344.81	2.04	2.04
296.31	2.67	2.67
279.31	1.92	1.92
295.35	2.86	2.86
305.35	2.60	2.60
306.33	1.99	1.99
321.34	1.89	1.89
358.83	2.43	2.43
358.83	2.43	2.43
299.31	2.61	2.61
317.30	2.75	2.75
330.78	2.41	2.41
320.36	2.50	2.50
346.39	3.03	3.03
283.34	2.82	2.82
372.86	2.82	2.82
294.32	2.23	2.23
287.30	2.50	2.50
295.35	2.86	2.86
301.38	2.84	2.84
346.42	2.03	2.03
319.37	2.79	2.79
334.39	2.49	2.49
283.34	2.67	2.67
331.38	3.49	3.49
283.34	2.67	2.67
319.31	2.94	2.94
305.29	2.64	2.64
283.34	2.67	2.67
346.42	2.03	2.03
332.39	1.30	1.30
332.39	1.30	1.30
419.49	4.55	4.55
319.37	2.79	2.79
297.36	3.06	3.06
287.30	2.50	2.50
313.34	3.04	3.04
299.33	2.37	2.37
285.31	1.81	1.81
299.33	2.37	2.37
381.47	2.49	2.49
406.45	4.52	4.52
293.29	1.72	1.72
321.34	2.76	2.76
347.38	3.30	3.30
287.30	2.50	2.50
313.34	3.04	3.04
362.23	3.43	3.43
325.37	2.90	2.90
339.40	3.15	3.15
312.33	0.93	0.93
303.32	3.39	3.39
303.32	3.39	3.39
331.38	3.19	3.19
304.36	3.20	3.20
304.36	3.20	3.20
318.38	3.51	3.51
348.20	3.12	3.12
392.26	3.40	3.40
360.22	3.27	3.27
326.36	1.32	1.32
339.40	3.29	3.29
313.36	2.67	2.67
317.35	3.18	3.18
386.24	4.49	4.49
293.33	2.53	2.53
292.35	3.14	3.14
318.38	3.67	3.67
374.24	3.66	3.66
287.30	2.50	2.50
302.31	1.44	1.44
327.39	2.85	2.85
343.39	1.72	1.72
343.39	1.72	1.72
365.44	4.47	4.47
318.34	1.71	1.71
306.37	3.15	3.15
332.41	3.68	3.68
293.33	2.53	2.53
302.31	1.44	1.44
312.31	2.22	2.22
326.34	2.61	2.61
339.40	3.21	3.21
285.31	2.01	2.01
327.39	3.06	3.06
315.38	3.64	3.64
331.42	4.27	4.27
319.37	3.07	3.07
308.35	2.11	2.11
293.33	2.53	2.53
299.31	2.65	2.65
300.30	1.06	1.06
313.34	3.04	3.04
325.37	2.67	2.67
353.43	3.60	3.60
377.45	4.94	4.94
299.34	2.86	2.86
319.37	3.07	3.07
311.32	2.67	2.67
292.35	3.14	3.14
327.36	3.28	3.28
314.32	1.45	1.45
314.32	1.45	1.45
367.45	3.99	3.99
343.39	2.68	2.68
319.37	3.16	3.16
319.37	3.52	3.52
338.80	3.86	3.86
318.38	3.67	3.67
293.33	2.30	2.30
320.36	2.95	2.95
315.31	1.88	1.88
315.31	1.88	1.88
341.39	3.82	3.82
313.36	2.67	2.67
327.39	3.06	3.06
329.36	1.48	1.48
304.36	3.20	3.20
330.40	3.74	3.74
276.30	2.16	2.16
292.35	3.14	3.14
318.38	3.67	3.67
342.38	1.92	1.92
416.42	2.86	2.86
315.34	1.46	1.46
283.34	2.67	2.67
284.32	1.94	1.94
301.35	3.28	3.28
287.33	3.27	3.27
289.34	3.25	3.25
392.46	4.39	4.39
418.50	4.93	4.93