ID: ALA1243971
Type: Binding
Description: Inhibition of recombinant PI4Kbeta by radioactive phosphotransfer assay in presence of 10 uM ATP
Bioactivity
Activity Types for Assay ALA1243971
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
319.37 | 3.07 | 3.07 |
269.31 | 2.36 | 2.36 |
317.40 | 3.98 | 3.98 |
325.37 | 2.82 | 2.82 |
304.36 | 3.20 | 3.20 |
275.31 | 2.77 | 2.77 |
265.28 | 1.49 | 1.49 |
264.29 | 2.09 | 2.09 |
255.24 | 1.33 | 1.33 |
281.34 | 2.83 | 2.83 |
211.23 | 1.60 | 1.60 |
225.25 | 1.91 | 1.91 |
225.25 | 1.91 | 1.91 |
225.25 | 1.91 | 1.91 |
239.28 | 2.22 | 2.22 |
267.34 | 2.90 | 2.90 |
269.31 | 2.36 | 2.36 |
227.23 | 1.31 | 1.31 |
268.32 | 2.97 | 2.97 |
241.25 | 1.62 | 1.62 |
255.28 | 1.63 | 1.63 |
320.15 | 2.08 | 2.08 |
257.25 | 1.32 | 1.32 |
271.28 | 1.33 | 1.33 |
227.23 | 1.31 | 1.31 |
226.24 | 1.18 | 1.18 |
226.24 | 1.18 | 1.18 |
256.23 | 1.51 | 1.51 |
256.23 | 1.51 | 1.51 |
254.30 | 2.05 | 2.05 |
255.29 | 1.45 | 1.45 |
271.28 | 2.06 | 2.06 |
265.32 | 2.21 | 2.21 |
261.29 | 2.76 | 2.76 |
398.47 | 4.01 | 4.01 |
402.39 | 3.62 | 3.62 |
301.33 | 2.80 | 2.80 |
303.75 | 3.02 | 3.02 |
298.35 | 2.25 | 2.25 |
356.43 | 2.46 | 2.46 |
310.36 | 2.48 | 2.48 |
301.35 | 3.41 | 3.41 |
303.37 | 3.81 | 3.81 |
293.33 | 3.40 | 3.40 |
319.37 | 3.94 | 3.94 |
295.31 | 2.19 | 2.19 |
348.20 | 3.12 | 3.12 |
318.77 | 1.95 | 1.95 |
318.77 | 1.95 | 1.95 |
315.76 | 3.16 | 3.16 |
324.39 | 2.78 | 2.78 |
283.34 | 2.15 | 2.15 |
292.35 | 2.72 | 2.72 |
329.41 | 4.34 | 4.34 |
351.41 | 4.28 | 4.28 |
309.33 | 1.83 | 1.83 |
295.35 | 2.59 | 2.59 |
311.35 | 2.43 | 2.43 |
308.35 | 2.84 | 2.84 |
329.79 | 3.55 | 3.55 |
330.78 | 1.97 | 1.97 |
331.76 | 2.40 | 2.40 |
292.35 | 2.72 | 2.72 |
278.32 | 2.53 | 2.53 |
296.31 | 2.67 | 2.67 |
330.40 | 3.74 | 3.74 |
318.38 | 3.51 | 3.51 |
338.80 | 3.86 | 3.86 |
337.41 | 3.68 | 3.68 |
331.76 | 2.40 | 2.40 |
344.81 | 2.19 | 2.19 |
344.81 | 2.04 | 2.04 |
296.31 | 2.67 | 2.67 |
279.31 | 1.92 | 1.92 |
295.35 | 2.86 | 2.86 |
305.35 | 2.60 | 2.60 |
306.33 | 1.99 | 1.99 |
321.34 | 1.89 | 1.89 |
358.83 | 2.43 | 2.43 |
358.83 | 2.43 | 2.43 |
299.31 | 2.61 | 2.61 |
317.30 | 2.75 | 2.75 |
330.78 | 2.41 | 2.41 |
320.36 | 2.50 | 2.50 |
346.39 | 3.03 | 3.03 |
283.34 | 2.82 | 2.82 |
372.86 | 2.82 | 2.82 |
294.32 | 2.23 | 2.23 |
287.30 | 2.50 | 2.50 |
295.35 | 2.86 | 2.86 |
301.38 | 2.84 | 2.84 |
346.42 | 2.03 | 2.03 |
319.37 | 2.79 | 2.79 |
334.39 | 2.49 | 2.49 |
283.34 | 2.67 | 2.67 |
331.38 | 3.49 | 3.49 |
283.34 | 2.67 | 2.67 |
319.31 | 2.94 | 2.94 |
305.29 | 2.64 | 2.64 |
283.34 | 2.67 | 2.67 |
346.42 | 2.03 | 2.03 |
332.39 | 1.30 | 1.30 |
332.39 | 1.30 | 1.30 |
419.49 | 4.55 | 4.55 |
319.37 | 2.79 | 2.79 |
297.36 | 3.06 | 3.06 |
287.30 | 2.50 | 2.50 |
313.34 | 3.04 | 3.04 |
299.33 | 2.37 | 2.37 |
285.31 | 1.81 | 1.81 |
299.33 | 2.37 | 2.37 |
381.47 | 2.49 | 2.49 |
406.45 | 4.52 | 4.52 |
293.29 | 1.72 | 1.72 |
321.34 | 2.76 | 2.76 |
347.38 | 3.30 | 3.30 |
287.30 | 2.50 | 2.50 |
313.34 | 3.04 | 3.04 |
362.23 | 3.43 | 3.43 |
325.37 | 2.90 | 2.90 |
339.40 | 3.15 | 3.15 |
312.33 | 0.93 | 0.93 |
303.32 | 3.39 | 3.39 |
303.32 | 3.39 | 3.39 |
331.38 | 3.19 | 3.19 |
304.36 | 3.20 | 3.20 |
304.36 | 3.20 | 3.20 |
318.38 | 3.51 | 3.51 |
348.20 | 3.12 | 3.12 |
392.26 | 3.40 | 3.40 |
360.22 | 3.27 | 3.27 |
326.36 | 1.32 | 1.32 |
339.40 | 3.29 | 3.29 |
313.36 | 2.67 | 2.67 |
317.35 | 3.18 | 3.18 |
386.24 | 4.49 | 4.49 |
293.33 | 2.53 | 2.53 |
292.35 | 3.14 | 3.14 |
318.38 | 3.67 | 3.67 |
374.24 | 3.66 | 3.66 |
287.30 | 2.50 | 2.50 |
302.31 | 1.44 | 1.44 |
327.39 | 2.85 | 2.85 |
343.39 | 1.72 | 1.72 |
343.39 | 1.72 | 1.72 |
365.44 | 4.47 | 4.47 |
318.34 | 1.71 | 1.71 |
306.37 | 3.15 | 3.15 |
332.41 | 3.68 | 3.68 |
293.33 | 2.53 | 2.53 |
302.31 | 1.44 | 1.44 |
312.31 | 2.22 | 2.22 |
326.34 | 2.61 | 2.61 |
339.40 | 3.21 | 3.21 |
285.31 | 2.01 | 2.01 |
327.39 | 3.06 | 3.06 |
315.38 | 3.64 | 3.64 |
331.42 | 4.27 | 4.27 |
319.37 | 3.07 | 3.07 |
308.35 | 2.11 | 2.11 |
293.33 | 2.53 | 2.53 |
299.31 | 2.65 | 2.65 |
300.30 | 1.06 | 1.06 |
313.34 | 3.04 | 3.04 |
325.37 | 2.67 | 2.67 |
353.43 | 3.60 | 3.60 |
377.45 | 4.94 | 4.94 |
299.34 | 2.86 | 2.86 |
319.37 | 3.07 | 3.07 |
311.32 | 2.67 | 2.67 |
292.35 | 3.14 | 3.14 |
327.36 | 3.28 | 3.28 |
314.32 | 1.45 | 1.45 |
314.32 | 1.45 | 1.45 |
367.45 | 3.99 | 3.99 |
343.39 | 2.68 | 2.68 |
319.37 | 3.16 | 3.16 |
319.37 | 3.52 | 3.52 |
338.80 | 3.86 | 3.86 |
318.38 | 3.67 | 3.67 |
293.33 | 2.30 | 2.30 |
320.36 | 2.95 | 2.95 |
315.31 | 1.88 | 1.88 |
315.31 | 1.88 | 1.88 |
341.39 | 3.82 | 3.82 |
313.36 | 2.67 | 2.67 |
327.39 | 3.06 | 3.06 |
329.36 | 1.48 | 1.48 |
304.36 | 3.20 | 3.20 |
330.40 | 3.74 | 3.74 |
276.30 | 2.16 | 2.16 |
292.35 | 3.14 | 3.14 |
318.38 | 3.67 | 3.67 |
342.38 | 1.92 | 1.92 |
416.42 | 2.86 | 2.86 |
315.34 | 1.46 | 1.46 |
283.34 | 2.67 | 2.67 |
284.32 | 1.94 | 1.94 |
301.35 | 3.28 | 3.28 |
287.33 | 3.27 | 3.27 |
289.34 | 3.25 | 3.25 |
392.46 | 4.39 | 4.39 |
418.50 | 4.93 | 4.93 |