Basic Information
ID: ALA1246842
Type: Binding
Description: Inhibition of HCV recombinant His6x-tagged NS5B Cdelta55 polymerase-mediated RNA synthesis expressed in Escherichia coli BL21(DE3) assessed as reduction of pppGpC accumulation after 15 mins
Format: BAO_0000019
Organism: Hepatitis C virus
Target: Unchecked(ALA612545)
Document: ALA1240527
Inhibition of HCV recombinant His6x-tagged NS5B Cdelta55 polymerase-mediated RNA synthesis expressed in Escherichia coli BL21(DE3) assessed as reduction of pppGpC accumulation after 15 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1246842
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 783.49 | -3.07 | -3.07 |
| 861.54 | -2.07 | -2.07 |
| 845.54 | -1.04 | -1.04 |
| 767.49 | -2.31 | -2.31 |
| 773.56 | -2.24 | -2.24 |
| 721.60 | -1.16 | -1.16 |
| 891.44 | -2.19 | -2.19 |
| 897.50 | -2.12 | -2.12 |
| 811.55 | -2.03 | -2.03 |
| 891.44 | -2.19 | -2.19 |
| 891.44 | -2.19 | -2.19 |
| 897.50 | -2.12 | -2.12 |
| 897.50 | -2.12 | -2.12 |
| 811.55 | -2.03 | -2.03 |
| 811.55 | -2.03 | -2.03 |
| 767.49 | -2.04 | -2.04 |
| 767.49 | -2.04 | -2.04 |
| 767.49 | -2.04 | -2.04 |
| 783.49 | -3.07 | -3.07 |
| 783.49 | -3.07 | -3.07 |
| 845.54 | -1.04 | -1.04 |
| 845.54 | -1.04 | -1.04 |
| 861.54 | -2.07 | -2.07 |
| 861.54 | -2.07 | -2.07 |