Assay Report Card

Basic Information

ID: ALA1247999

Type: Functional

Description: Inhibition of aurora B in human COLO205 cells xenografted in CD1 mouse assessed as reduction of phosphorylated histone H3 level at 50 mg/kg, po after 3 to 6 hrs by immunofluorescence-based flow cytometry

Organism: Mus musculus

Strain: CD1

Cell type: COLO 205

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
515.556.876.87