Basic Information
ID: ALA1260645
Type: Binding
Description: Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLL
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1260645
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.61 | 2.92 | 2.92 |
| 450.57 | 3.04 | 3.04 |
| 565.70 | 4.59 | 4.59 |
| 536.66 | 4.74 | 4.74 |
| 512.64 | 1.64 | 1.64 |
| 492.61 | 2.22 | 2.22 |
| 565.70 | 4.59 | 4.59 |
| 495.65 | 3.30 | 3.30 |
| 578.74 | 5.41 | 5.41 |
| 554.68 | 3.71 | 3.71 |
| 503.63 | 3.23 | 3.23 |
| 490.59 | 2.32 | 2.32 |
| 514.62 | 2.79 | 2.79 |
| 514.62 | 2.79 | 2.79 |
| 439.55 | 1.91 | 1.91 |
| 453.57 | 2.30 | 2.30 |
| 596.76 | 3.37 | 3.37 |
| 485.61 | 4.19 | 4.19 |
| 518.44 | 2.63 | 2.63 |
| 491.64 | 4.25 | 4.25 |
| 486.60 | 3.58 | 3.58 |
| 574.72 | 2.43 | 2.43 |
| 529.46 | 3.80 | 3.80 |
| 543.49 | 3.81 | 3.81 |
| 503.63 | 3.23 | 3.23 |
| 503.63 | 3.23 | 3.23 |
| 495.63 | 2.98 | 2.98 |
| 503.63 | 3.31 | 3.31 |
| 529.67 | 3.84 | 3.84 |
| 529.67 | 3.84 | 3.84 |
| 529.67 | 3.84 | 3.84 |
| 529.67 | 3.84 | 3.84 |
| 609.16 | 3.08 | 3.08 |
| 592.71 | 2.57 | 2.57 |
| 592.71 | 2.57 | 2.57 |
| 610.70 | 2.71 | 2.71 |
| 646.68 | 2.99 | 2.99 |
| 564.71 | 4.01 | 4.01 |
| 437.53 | 1.36 | 1.36 |
| 508.60 | 2.75 | 2.75 |
| 507.62 | 2.15 | 2.15 |
| 540.69 | 4.72 | 4.72 |
| 575.70 | 1.82 | 1.82 |
| 479.57 | 2.52 | 2.52 |
| 575.70 | 1.82 | 1.82 |
| 479.57 | 2.52 | 2.52 |
| 576.69 | 1.22 | 1.22 |
| 495.63 | 2.98 | 2.98 |
| 508.61 | 2.53 | 2.53 |
| 524.68 | 3.00 | 3.00 |
| 507.62 | 1.96 | 1.96 |
| 492.65 | 3.96 | 3.96 |
| 510.64 | 4.10 | 4.10 |
| 493.64 | 3.36 | 3.36 |
| 453.57 | 2.13 | 2.13 |
| 451.60 | 3.54 | 3.54 |
| 449.58 | 3.29 | 3.29 |