Basic Information
ID: ALA1267247
Type: Functional
Description: Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay
Organism: Plasmodium falciparum
Strain: D10
Activity Charts
Bioactivity
Activity Types for Assay ALA1267247
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 391.56 | 6.86 | 6.86 |
| 290.32 | 1.26 | 1.26 |
| 270.24 | 2.58 | 2.58 |
| 186.16 | -0.05 | -0.05 |
| 330.75 | 1.89 | 1.89 |
| 329.36 | 4.06 | 4.06 |
| 394.42 | 3.70 | 3.70 |
| 315.76 | 4.04 | 4.04 |
| 214.22 | 0.73 | 0.73 |
| 302.37 | 3.57 | 3.57 |
| 375.87 | 4.43 | 4.43 |
| 335.45 | 5.43 | 5.43 |
| 444.49 | -0.14 | -0.14 |
| 336.33 | -0.13 | -0.13 |
| 808.66 | 6.38 | 6.38 |
| 414.41 | 2.41 | 2.41 |
| 348.36 | 2.08 | 2.08 |
| 369.37 | 3.52 | 3.52 |
| 380.49 | 6.09 | 6.09 |
| 410.49 | 3.59 | 3.59 |
| 853.92 | 3.74 | 3.74 |
| 275.35 | 1.77 | 1.77 |
| 182.23 | 3.02 | 3.02 |
| 477.58 | 5.48 | 5.48 |
| 304.22 | 3.38 | 3.38 |
| 422.35 | 2.45 | 2.45 |
| 449.64 | 4.85 | 4.85 |
| 308.38 | 3.79 | 3.79 |
| 314.47 | 4.72 | 4.72 |
| 426.56 | 4.13 | 4.13 |
| 344.85 | 5.38 | 5.38 |
| 300.44 | 5.60 | 5.60 |
| 431.39 | 5.51 | 5.51 |
| 354.46 | 3.20 | 3.20 |
| 399.44 | 2.87 | 2.87 |
| 242.27 | 2.75 | 2.75 |
| 325.54 | 5.13 | 5.13 |
| 403.98 | 3.94 | 3.94 |
| 253.27 | 0.83 | 0.83 |
| 285.69 | 2.77 | 2.77 |
| 331.35 | 4.65 | 4.65 |
| 360.35 | 4.85 | 4.85 |
| 314.34 | 3.03 | 3.03 |
| 471.69 | 6.45 | 6.45 |
| 393.46 | 3.28 | 3.28 |
| 403.53 | 4.06 | 4.06 |
| 522.61 | 2.97 | 2.97 |
| 246.31 | 4.49 | 4.49 |
| 280.36 | 1.96 | 1.96 |
| 360.84 | 4.68 | 4.68 |
| 320.43 | 5.17 | 5.17 |
| 417.55 | 4.18 | 4.18 |
| 110.11 | 1.10 | 1.10 |
| 382.46 | 2.86 | 2.86 |
| 352.74 | 5.22 | 5.22 |
| 301.69 | -1.33 | -1.33 |
| 347.86 | 4.47 | 4.47 |
| 472.09 | 8.01 | 8.01 |
| 608.69 | 4.17 | 4.17 |
| 563.65 | 6.00 | 6.00 |
| 454.45 | 0.27 | 0.27 |
| 342.44 | 3.48 | 3.48 |
| 369.47 | 3.46 | 3.46 |
| 516.55 | 5.40 | 5.40 |
| 380.50 | 3.12 | 3.12 |
| 582.79 | 6.80 | 6.80 |
| 1429.19 | ||
| 465.80 | ||
| 305.21 | 1.93 | 1.93 |
| 475.58 | 5.31 | 5.31 |
| 368.52 | 5.11 | 5.11 |
| 434.20 | 6.77 | 6.77 |
| 588.56 | 1.34 | 1.34 |
| 370.46 | 5.59 | 5.59 |
| 196.20 | 0.64 | 0.64 |
| 481.48 | 3.98 | 3.98 |
| 1202.63 | ||
| 274.18 | ||
| 544.74 | 1.06 | 1.06 |
| 327.18 | 4.09 | 4.09 |
| 336.24 | 1.74 | 1.74 |
| 504.64 | -0.02 | -0.02 |
| 466.56 | 2.88 | 2.88 |
| 306.32 | 2.59 | 2.59 |
| 294.31 | 2.32 | 2.32 |
| 297.27 | 2.30 | 2.30 |
| 322.36 | 2.75 | 2.75 |
| 515.87 | 4.81 | 4.81 |
| 340.85 | 4.30 | 4.30 |
| 379.46 | 2.25 | 2.25 |
| 331.80 | 3.33 | 3.33 |
| 290.41 | 3.79 | 3.79 |
| 436.62 | 7.51 | 7.51 |
| 448.44 | 1.65 | 1.65 |
| 244.25 | 2.68 | 2.68 |
| 304.31 | 3.37 | 3.37 |
| 382.89 | 4.89 | 4.89 |
| 350.46 | 4.15 | 4.15 |
| 326.44 | 3.52 | 3.52 |
| 317.22 | 2.60 | 2.60 |
| 246.31 | 1.38 | 1.38 |
| 327.43 | 5.74 | 5.74 |
| 385.51 | 1.20 | 1.20 |
| 665.68 | 5.03 | 5.03 |
| 451.35 | 3.60 | 3.60 |
| 268.23 | 0.97 | 0.97 |
| 202.17 | 1.23 | 1.23 |
| 282.39 | 4.42 | 4.42 |
| 616.84 | 5.75 | 5.75 |
| 304.39 | 3.15 | 3.15 |
| 293.32 | 4.03 | 4.03 |
| 264.33 | 3.25 | 3.25 |
| 213.24 | 3.51 | 3.51 |
| 347.41 | 4.24 | 4.24 |
| 337.94 | 4.33 | 4.33 |
| 650.76 | 3.93 | 3.93 |
| 379.44 | 3.68 | 3.68 |
| 286.36 | 3.59 | 3.59 |
| 313.79 | 3.43 | 3.43 |
| 510.06 | 6.08 | 6.08 |
| 497.50 | 1.02 | 1.02 |
| 391.47 | 4.88 | 4.88 |
| 134.14 | 0.15 | 0.15 |
| 446.37 | 3.58 | 3.58 |
| 371.22 | 4.05 | 4.05 |
| 393.96 | 3.34 | 3.34 |
| 418.30 | 3.52 | 3.52 |
| 284.31 | 2.90 | 2.90 |
| 399.56 | 5.72 | 5.72 |
| 527.58 | 6.17 | 6.17 |
| 165.71 | 1.88 | 1.88 |
| 277.28 | 4.42 | 4.42 |
| 256.26 | 2.70 | 2.70 |
| 187.16 | 0.85 | 0.85 |
| 448.40 | 4.73 | 4.73 |
| 416.95 | 4.61 | 4.61 |
| 410.61 | 4.27 | 4.27 |
| 491.07 | 5.09 | 5.09 |
| 531.44 | 4.21 | 4.21 |
| 389.97 | 4.66 | 4.66 |
| 361.53 | 5.33 | 5.33 |
| 345.47 | 3.94 | 3.94 |
| 430.54 | 2.72 | 2.72 |
| 266.26 | -1.37 | -1.37 |
| 270.37 | 3.82 | 3.82 |
| 318.50 | 4.60 | 4.60 |
| 909.07 | 3.99 | 3.99 |
| 461.56 | 5.86 | 5.86 |
| 425.92 | 3.35 | 3.35 |
| 418.45 | 2.97 | 2.97 |
| 130.08 | -0.80 | -0.80 |
| 840.12 | 3.85 | 3.85 |
| 362.23 | 4.06 | 4.06 |
| 357.41 | -1.46 | -1.46 |
| 440.42 | 0.24 | 0.24 |
| 327.12 | 3.86 | 3.86 |
| 276.68 | 3.50 | 3.50 |
| 178.14 | 1.20 | 1.20 |
| 314.55 | -0.20 | -0.20 |
| 337.46 | 4.22 | 4.22 |
| 384.26 | 3.96 | 3.96 |
| 376.91 | 3.62 | 3.62 |
| 310.40 | 1.73 | 1.73 |
| 324.83 | 2.48 | 2.48 |
| 417.63 | 6.79 | 6.79 |
| 356.18 | 3.42 | 3.42 |
| 366.46 | 4.29 | 4.29 |
| 241.25 | 1.91 | 1.91 |
| 383.83 | 3.72 | 3.72 |
| 308.34 | 2.88 | 2.88 |
| 218.21 | 1.57 | 1.57 |
| 312.45 | 4.64 | 4.64 |
| 249.34 | 2.80 | 2.80 |
| 377.34 | 3.29 | 3.29 |
| 189.64 | 0.60 | 0.60 |
| 419.87 | 1.78 | 1.78 |
| 301.52 | 4.15 | 4.15 |
| 360.37 | 2.57 | 2.57 |
| 367.79 | 3.43 | 3.43 |
| 566.42 | 5.33 | 5.33 |
| 728.76 | 7.22 | 7.22 |
| 425.51 | 4.01 | 4.01 |
| 311.78 | 0.72 | 0.72 |
| 465.44 | 4.40 | 4.40 |
| 923.05 | 3.52 | 3.52 |
| 248.32 | 2.76 | 2.76 |
| 295.81 | 2.58 | 2.58 |
| 299.77 | 0.57 | 0.57 |
| 234.73 | 2.70 | 2.70 |
| 398.73 | 3.68 | 3.68 |
| 263.31 | 1.33 | 1.33 |
| 352.87 | 5.43 | 5.43 |
| 300.83 | 3.08 | 3.08 |
| 316.88 | 3.88 | 3.88 |
| 397.92 | 3.23 | 3.23 |
| 302.85 | 3.53 | 3.53 |
| 370.67 | 3.03 | 3.03 |
| 472.89 | 5.97 | 5.97 |
| 523.50 | 5.32 | 5.32 |
| 477.43 | 5.39 | 5.39 |
| 410.74 | 3.93 | 3.93 |
| 339.87 | 4.89 | 4.89 |
| 374.28 | 3.41 | 3.41 |
| 295.81 | 2.58 | 2.58 |
| 513.51 | 5.09 | 5.09 |
| 342.70 | 5.18 | 5.18 |
| 443.97 | 4.95 | 4.95 |
| 390.91 | 2.65 | 2.65 |
| 355.33 | 4.89 | 4.89 |
| 328.29 | 3.37 | 3.37 |
| 323.87 | 4.70 | 4.70 |
| 419.15 | 4.02 | 4.02 |
| 331.84 | 3.63 | 3.63 |
| 344.84 | 0.53 | 0.53 |
| 387.81 | 1.80 | 1.80 |
| 376.58 | 5.66 | 5.66 |
| 316.47 | 4.18 | 4.18 |
| 357.16 | ||
| 388.65 | 1.85 | 1.85 |
| 340.39 | 3.94 | 3.94 |
| 405.80 | 4.40 | 4.40 |
| 371.46 | 2.64 | 2.64 |
| 306.37 | 1.07 | 1.07 |
| 452.56 | 3.91 | 3.91 |
| 414.37 | 3.05 | 3.05 |
| 681.78 | 6.94 | 6.94 |
| 603.76 | 4.11 | 4.11 |
| 320.25 | 1.99 | 1.99 |
| 583.60 | 4.00 | 4.00 |
| 364.87 | 2.14 | 2.14 |
| 515.99 | 3.68 | 3.68 |
| 299.85 | 4.30 | 4.30 |
| 403.54 | 4.42 | 4.42 |
| 337.85 | 2.96 | 2.96 |
| 320.89 | 4.24 | 4.24 |
| 501.32 | 0.26 | 0.26 |
| 345.96 | 4.40 | 4.40 |
| 282.56 | 1.55 | 1.55 |
| 750.71 | 3.19 | 3.19 |
| 679.80 | 2.08 | 2.08 |
| 291.14 | 1.81 | 1.81 |
| 547.59 | 1.72 | 1.72 |
| 490.03 | 4.58 | 4.58 |
| 1736.18 | ||
| 311.86 | 4.55 | 4.55 |
| 351.32 | 4.53 | 4.53 |
| 320.89 | 4.24 | 4.24 |
| 340.29 | 4.19 | 4.19 |
| 459.97 | 5.10 | 5.10 |
| 455.51 | 1.92 | 1.92 |
| 493.94 | 0.19 | 0.19 |
| 480.10 | 3.47 | 3.47 |
| 407.05 | 5.89 | 5.89 |
| 410.51 | 4.12 | 4.12 |
| 313.87 | 4.17 | 4.17 |
| 377.91 | 3.24 | 3.24 |
| 345.79 | 4.44 | 4.44 |
| 388.89 | 5.26 | 5.26 |
| 335.42 | 1.91 | 1.91 |
| 445.90 | 3.77 | 3.77 |
| 299.85 | 3.83 | 3.83 |
| 593.64 | 4.21 | 4.21 |
| 687.71 | 10.29 | 10.29 |
| 522.62 | 4.60 | 4.60 |
| 246.22 | 1.93 | 1.93 |
| 348.24 | -0.34 | -0.34 |
| 313.87 | 4.21 | 4.21 |
| 450.97 | 3.57 | 3.57 |
| 168.15 | -0.14 | -0.14 |
| 175.14 | 2.19 | 2.19 |
| 137.57 | -0.44 | -0.44 |
| 219.67 | 0.35 | 0.35 |
| 373.17 | 1.27 | 1.27 |
| 318.26 | 2.76 | 2.76 |
| 127.53 | -1.04 | -1.04 |
| 535.13 | 4.94 | 4.94 |
| 198.22 | 2.78 | 2.78 |
| 286.40 | 3.70 | 3.70 |
| 707.85 | 2.72 | 2.72 |
| 276.29 | 2.01 | 2.01 |
| 585.58 | 2.88 | 2.88 |
| 328.29 | 3.37 | 3.37 |
| 294.15 | -0.60 | -0.60 |
| 592.12 | 4.26 | 4.26 |
| 243.29 | 2.52 | 2.52 |
| 173.58 | 0.24 | 0.24 |
| 285.81 | 2.15 | 2.15 |
| 299.77 | 0.22 | 0.22 |
| 281.02 | -0.43 | -0.43 |
| 726.92 | 5.21 | 5.21 |
| 273.78 | 2.73 | 2.73 |
| 328.23 | 2.39 | 2.39 |
| 248.76 | 2.25 | 2.25 |
| 641.16 | 3.54 | 3.54 |
| 235.34 | 2.95 | 2.95 |
| 280.84 | 3.15 | 3.15 |
| 203.67 | 0.86 | 0.86 |
| 211.09 | 0.36 | 0.36 |
| 324.25 | 3.67 | 3.67 |
| 386.67 | 2.73 | 2.73 |
| 386.03 | ||
| 377.91 | 3.24 | 3.24 |
| 429.93 | 4.51 | 4.51 |
| 534.06 | 5.03 | 5.03 |
| 349.28 | 2.51 | 2.51 |
| 352.33 | 5.19 | 5.19 |
| 455.19 | 4.04 | 4.04 |
| 460.98 | 4.34 | 4.34 |
| 376.95 | 4.83 | 4.83 |
| 475.54 | 3.77 | 3.77 |
| 430.95 | 4.04 | 4.04 |
| 432.00 | 4.55 | 4.55 |
| 358.36 | -0.24 | -0.24 |
| 296.32 | 1.15 | 1.15 |
| 523.63 | 5.53 | 5.53 |
| 364.82 | 4.43 | 4.43 |
| 450.42 | 3.26 | 3.26 |
| 557.09 | 5.58 | 5.58 |
| 350.26 | 2.72 | 2.72 |
| 643.22 | -1.24 | -1.24 |
| 321.80 | 2.85 | 2.85 |
| 427.03 | 3.68 | 3.68 |
| 545.52 | 2.42 | 2.42 |
| 462.54 | 2.81 | 2.81 |
| 497.62 | 5.16 | 5.16 |
| 526.68 | 6.84 | 6.84 |
| 399.31 | 5.56 | 5.56 |
| 480.90 | -0.35 | -0.35 |
| 375.94 | 4.02 | 4.02 |
| 317.82 | 3.15 | 3.15 |
| 452.67 | 4.40 | 4.40 |
| 454.74 | 3.49 | 3.49 |
| 439.83 | 5.73 | 5.73 |
| 328.67 | 4.79 | 4.79 |
| 394.34 | 4.06 | 4.06 |
| 420.40 | 2.98 | 2.98 |
| 397.99 | 4.84 | 4.84 |
| 345.91 | 4.20 | 4.20 |
| 598.48 | 5.68 | 5.68 |
| 345.79 | 4.44 | 4.44 |
| 334.50 | 3.57 | 3.57 |
| 401.84 | 1.07 | 1.07 |
| 398.42 | 2.91 | 2.91 |
| 313.87 | 2.61 | 2.61 |
| 344.41 | 2.22 | 2.22 |
| 301.83 | 3.51 | 3.51 |
| 487.69 | 6.20 | 6.20 |
| 397.99 | 4.84 | 4.84 |
| 430.09 | -0.05 | -0.05 |
| 519.42 | 4.40 | 4.40 |
| 335.94 | 5.55 | 5.55 |
| 343.81 | 4.29 | 4.29 |
| 415.49 | 3.66 | 3.66 |
| 293.84 | 3.10 | 3.10 |
| 303.79 | 2.65 | 2.65 |
| 405.80 | 4.40 | 4.40 |
| 445.52 | 2.52 | 2.52 |
| 437.59 | 5.43 | 5.43 |
| 710.49 | 6.17 | 6.17 |
| 334.37 | 4.94 | 4.94 |
| 431.94 | 3.22 | 3.22 |
| 365.90 | 3.26 | 3.26 |
| 356.22 | 0.54 | 0.54 |
| 376.29 | 3.27 | 3.27 |
| 441.96 | 3.58 | 3.58 |
| 422.36 | 3.93 | 3.93 |
| 383.85 | 3.33 | 3.33 |
| 374.35 | 1.55 | 1.55 |
| 423.34 | 4.33 | 4.33 |
| 327.90 | 4.56 | 4.56 |
| 377.31 | 2.83 | 2.83 |
| 308.43 | 3.90 | 3.90 |
| 328.80 | 3.17 | 3.17 |
| 352.30 | 3.13 | 3.13 |
| 361.53 | 4.05 | 4.05 |
| 512.65 | 5.02 | 5.02 |
| 521.10 | 5.10 | 5.10 |
| 334.37 | 1.76 | 1.76 |
| 395.47 | 4.23 | 4.23 |
| 590.58 | 2.32 | 2.32 |
| 333.29 | 0.35 | 0.35 |
| 530.41 | 3.02 | 3.02 |
| 507.83 | 2.38 | 2.38 |
| 538.70 | 5.67 | 5.67 |
| 419.35 | 3.36 | 3.36 |
| 390.15 | 3.84 | 3.84 |
| 373.92 | 4.24 | 4.24 |
| 374.67 | 4.10 | 4.10 |
| 345.79 | 4.44 | 4.44 |
| 445.88 | 4.79 | 4.79 |
| 364.24 | 2.56 | 2.56 |
| 294.31 | 2.32 | 2.32 |
| 451.39 | 5.11 | 5.11 |
| 511.60 | 3.84 | 3.84 |
| 437.96 | 4.22 | 4.22 |
| 443.40 | 2.53 | 2.53 |
| 299.33 | 2.87 | 2.87 |
| 429.60 | 5.41 | 5.41 |
| 487.52 | 5.04 | 5.04 |
| 319.27 | 0.09 | 0.09 |
| 329.79 | 2.77 | 2.77 |
| 302.12 | -1.08 | -1.08 |
| 510.45 | 4.31 | 4.31 |
| 164.30 | 1.30 | 1.30 |
| 426.30 | 3.09 | 3.09 |
| 340.47 | 2.93 | 2.93 |
| 507.45 | 4.60 | 4.60 |
| 436.43 | 3.31 | 3.31 |
| 444.26 | 2.02 | 2.02 |
| 568.56 | 5.27 | 5.27 |
| 465.42 | 3.41 | 3.41 |
| 392.29 | 3.34 | 3.34 |
| 315.84 | 3.96 | 3.96 |
| 446.09 | -0.35 | -0.35 |
| 524.59 | ||
| 320.82 | 2.95 | 2.95 |
| 782.96 | 3.17 | 3.17 |
| 734.72 | 3.82 | 3.82 |
| 378.34 | 5.07 | 5.07 |
| 206.18 | 1.29 | 1.29 |
| 723.70 | 3.28 | 3.28 |
| 435.23 | 4.33 | 4.33 |
| 458.42 | 5.87 | 5.87 |
| 582.70 | 2.05 | 2.05 |
| 782.96 | 3.17 | 3.17 |
| 469.54 | 1.94 | 1.94 |