Basic Information
ID: ALA1267431
Type: ADME
Description: Therapeutic index, ratio of IC50 against human THP1 cells to IC50 against Trypanosoma brucei
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA1267431
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.30 | 0.64 | 0.64 |
| 356.15 | 2.96 | 2.96 |
| 321.16 | 3.01 | 3.01 |
| 382.18 | 3.53 | 3.53 |
| 382.18 | 3.53 | 3.53 |
| 382.18 | 3.53 | 3.53 |
| 382.18 | 3.53 | 3.53 |
| 467.29 | 3.21 | 3.21 |
| 467.29 | 3.21 | 3.21 |
| 381.20 | 3.11 | 3.11 |
| 381.20 | 3.11 | 3.11 |
| 370.17 | 3.52 | 3.52 |
| 356.15 | 2.96 | 2.96 |
| 356.15 | 2.96 | 2.96 |
| 386.17 | 2.97 | 2.97 |
| 386.17 | 2.97 | 2.97 |
| 370.17 | 3.27 | 3.27 |
| 374.14 | 3.10 | 3.10 |
| 374.14 | 3.10 | 3.10 |
| 424.14 | 3.98 | 3.98 |
| 390.59 | 3.61 | 3.61 |
| 392.13 | 3.24 | 3.24 |