Basic Information
ID: ALA1273386
Type: Binding
Description: Inhibition of His6x-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) assessed as residual activity at 500 uM using H4(1-20) and [14C]-AdoMet by scintillation counting
Format: BAO_0000019
Target: Protein-arginine N-methyltransferase 1(ALA5524)
Document: ALA1268868
Inhibition of His6x-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) assessed as residual activity at 500 uM using H4(1-20) and [14C]-AdoMet by scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1273386
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.37 | 0.29 | 0.29 |
| 454.53 | 4.15 | 4.15 |
| 302.33 | -0.16 | -0.16 |
| 303.32 | 0.92 | 0.92 |
| 253.28 | 1.83 | 1.83 |
| 421.45 | 2.81 | 2.81 |
| 327.36 | 3.34 | 3.34 |
| 356.40 | 3.82 | 3.82 |
| 521.02 | 5.90 | 5.90 |
| 498.58 | 4.46 | 4.46 |
| 364.42 | 4.77 | 4.77 |
| 391.24 | 4.18 | 4.18 |
| 435.30 | 4.58 | 4.58 |
| 468.27 | 4.03 | 4.03 |
| 363.44 | 3.65 | 3.65 |
| 528.65 | 4.05 | 4.05 |
| 399.43 | 3.53 | 3.53 |
| 450.86 | 5.54 | 5.54 |
| 440.50 | 4.38 | 4.38 |
| 399.42 | 2.99 | 2.99 |