Basic Information
ID: ALA1273704
Type: Binding
Description: Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation counting
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Target: Squalene synthetase(ALA3815)
Document: ALA1268937
Inhibition of squalene synthase in rat liver microsomes assessed as [3H] FPP to squalene conversion level after 10 mins by scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1273704
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.44 | 3.77 | 3.77 |
| 324.22 | 1.95 | 1.95 |
| 354.24 | 1.96 | 1.96 |
| 394.31 | 2.88 | 2.88 |
| 408.34 | 3.27 | 3.27 |
| 364.28 | 2.87 | 2.87 |
| 378.31 | 3.26 | 3.26 |
| 430.34 | 3.62 | 3.62 |
| 470.41 | 4.55 | 4.55 |
| 484.43 | 4.93 | 4.93 |
| 400.32 | 3.61 | 3.61 |
| 440.38 | 4.54 | 4.54 |
| 454.41 | 4.93 | 4.93 |