Basic Information
ID: ALA1274344
Type: Functional
Description: Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at 0.1 uM at -60mV holding potential by two-electrode voltage-clamp electrophysiology
Format: BAO_0000219
Cell type: Oocyte
Target: Glutamate NMDA receptor; GRIN1/GRIN2A(ALA1907604)
Document: ALA1268910
Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at 0.1 uM at -60mV holding potential by two-electrode voltage-clamp electrophysiology: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1274344
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.61 | 1.03 | 1.03 |
| 523.77 | 3.65 | 3.65 |
| 524.71 | 1.35 | 1.35 |