Basic Information
ID: ALA1275002
Type: Binding
Description: Inhibition of PHLPP in human HT20 cells assessed as increase of phosphorylation of Akt on Ser 473 at 100 to 250 uM after 24 hrs by immunoblotting relative to control
Organism: Homo sapiens
Cell type: HT20
Activity Charts
Bioactivity
Activity Types for Assay ALA1275002
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 696.68 | 8.15 | 8.15 |
| 321.31 | 2.15 | 2.15 |
| 549.53 | 5.87 | 5.87 |
| 370.36 | 3.37 | 3.37 |
| 270.20 | 2.71 | 2.71 |
| 473.49 | 1.68 | 1.68 |
| 378.82 | 5.49 | 5.49 |
| 208.26 | 0.99 | 0.99 |
| 451.46 | 2.99 | 2.99 |
| 729.75 | 7.99 | 7.99 |
| 588.61 | 7.36 | 7.36 |
| 650.74 | 8.31 | 8.31 |
| 636.65 | 8.41 | 8.41 |
| 657.71 | 9.59 | 9.59 |
| 657.71 | 9.59 | 9.59 |
| 777.82 | 7.84 | 7.84 |
| 813.83 | 6.39 | 6.39 |
| 278.29 | 1.85 | 1.85 |
| 450.41 | 1.95 | 1.95 |
| 308.37 | 3.25 | 3.25 |
| 347.45 | 3.75 | 3.75 |
| 375.47 | 4.91 | 4.91 |
| 390.40 | 5.39 | 5.39 |
| 454.49 | 4.92 | 4.92 |
| 456.44 | 5.18 | 5.18 |
| 448.46 | 4.85 | 4.85 |
| 404.43 | 3.76 | 3.76 |
| 440.44 | 5.48 | 5.48 |
| 285.39 | 3.19 | 3.19 |
| 394.81 | 5.20 | 5.20 |