Basic Information
ID: ALA1282285
Type: Binding
Description: Inhibition of 50S ribosomal subunit purified from linezolid-,erythromycin-resistant Staphylococcus aureus A7820 with G2576U mutation in 23s rRNA assessed as inhibition of translation using in vitro transcribed mRNA encoding firefly luciferase
Organism: Staphylococcus aureus
Strain: A7820
Activity Charts
Bioactivity
Activity Types for Assay ALA1282285
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.35 | 1.12 | 1.12 |
| 323.13 | 0.91 | 0.91 |
| 410.41 | 1.99 | 1.99 |
| 438.46 | 2.36 | 2.36 |
| 409.42 | 2.59 | 2.59 |
| 417.46 | 3.40 | 3.40 |
| 535.53 | 1.97 | 1.97 |
| 358.22 | 1.38 | 1.38 |
| 357.39 | 2.41 | 2.41 |
| 414.44 | 1.53 | 1.53 |
| 399.43 | 1.94 | 1.94 |
| 361.45 | -1.07 | -1.07 |