Basic Information
ID: ALA1285217
Type: Binding
Description: Inhibition of SCD1 in HEK293A cell microsomes assessed as reduction in conversion of [14C]stearic acid to [14C]oleic acid after 30 mins
Format: BAO_0000251
Organism: Homo sapiens
Cell type: HEK293-A
Subcellular Fraction: Microsome
Target: Acyl-CoA desaturase(ALA5555)
Document: ALA1275283
Inhibition of SCD1 in HEK293A cell microsomes assessed as reduction in conversion of [14C]stearic acid to [14C]oleic acid after 30 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1285217
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.50 | 4.90 | 4.90 |
| 474.95 | 4.53 | 4.53 |
| 476.49 | 4.15 | 4.15 |
| 454.53 | 4.19 | 4.19 |
| 458.50 | 4.02 | 4.02 |
| 440.51 | 3.88 | 3.88 |
| 440.51 | 3.88 | 3.88 |
| 440.51 | 3.88 | 3.88 |
| 415.50 | 3.17 | 3.17 |