Basic Information
ID: ALA1286450
Type: Binding
Description: Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiology assay
Organism: Rattus norvegicus
Tissue: Dorsal root ganglion
Activity Charts
Bioactivity
Activity Types for Assay ALA1286450
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 4.87 | 4.87 |
| 387.36 | 4.91 | 4.91 |
| 408.77 | 4.02 | 4.02 |
| 459.43 | 3.20 | 3.20 |
| 369.81 | 4.07 | 4.07 |
| 323.78 | 4.36 | 4.36 |
| 337.81 | 4.67 | 4.67 |
| 337.81 | 4.04 | 4.04 |
| 372.26 | 4.42 | 4.42 |
| 409.88 | 2.96 | 2.96 |
| 393.88 | 3.72 | 3.72 |
| 347.42 | 4.41 | 4.41 |
| 333.39 | 4.10 | 4.10 |
| 347.42 | 3.78 | 3.78 |
| 328.38 | 3.88 | 3.88 |
| 358.40 | 4.05 | 4.05 |
| 328.38 | 3.25 | 3.25 |
| 373.33 | 4.60 | 4.60 |
| 387.36 | 4.28 | 4.28 |