Basic Information
ID: ALA1286959
Type: Binding
Description: Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPH
Organism: Homo sapiens
Cell type: PMN
Activity Charts
Bioactivity
Activity Types for Assay ALA1286959
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 289.72 | 1.98 | 1.98 |
| 273.27 | 1.47 | 1.47 |
| 193.21 | -0.13 | -0.13 |
| 289.72 | 1.98 | 1.98 |
| 270.29 | 0.78 | 0.78 |
| 442.83 | 2.73 | 2.73 |
| 478.00 | 3.24 | 3.24 |
| 392.44 | 2.36 | 2.36 |
| 444.90 | 2.14 | 2.14 |
| 366.81 | 2.89 | 2.89 |
| 441.52 | 4.12 | 4.12 |
| 321.34 | 2.43 | 2.43 |
| 451.91 | 2.72 | 2.72 |
| 314.35 | 0.89 | 0.89 |
| 432.46 | 3.15 | 3.15 |
| 332.36 | 2.23 | 2.23 |
| 369.43 | 0.58 | 0.58 |
| 360.42 | 2.49 | 2.49 |
| 345.40 | 3.03 | 3.03 |
| 375.38 | 2.57 | 2.57 |
| 410.86 | 2.98 | 2.98 |
| 415.28 | 3.60 | 3.60 |
| 383.43 | 1.37 | 1.37 |
| 349.37 | 2.98 | 2.98 |
| 346.39 | 2.29 | 2.29 |
| 398.83 | 3.08 | 3.08 |
| 465.47 | 3.07 | 3.07 |
| 374.40 | 2.37 | 2.37 |
| 380.83 | 2.94 | 2.94 |
| 384.80 | 3.02 | 3.02 |
| 472.57 | 4.10 | 4.10 |
| 508.00 | 3.54 | 3.54 |
| 346.39 | 2.54 | 2.54 |
| 417.86 | 3.43 | 3.43 |
| 473.56 | 3.35 | 3.35 |
| 452.94 | 3.79 | 3.79 |
| 484.96 | 3.94 | 3.94 |
| 446.48 | 1.19 | 1.19 |
| 492.55 | 5.17 | 5.17 |
| 490.99 | 3.98 | 3.98 |
| 467.93 | 3.51 | 3.51 |
| 471.95 | 4.21 | 4.21 |
| 480.52 | 3.60 | 3.60 |
| 388.43 | 2.67 | 2.67 |
| 479.97 | 3.00 | 3.00 |
| 485.98 | 4.41 | 4.41 |
| 408.85 | 3.02 | 3.02 |
| 338.39 | 2.45 | 2.45 |
| 488.98 | 3.55 | 3.55 |
| 473.92 | 3.69 | 3.69 |
| 418.48 | -0.34 | -0.34 |
| 307.71 | 2.12 | 2.12 |
| 430.29 | 4.04 | 4.04 |
| 399.81 | 3.39 | 3.39 |
| 361.40 | 2.90 | 2.90 |
| 280.29 | 1.20 | 1.20 |
| 312.33 | 1.28 | 1.28 |
| 369.78 | 3.48 | 3.48 |
| 371.87 | 4.02 | 4.02 |
| 333.78 | 1.82 | 1.82 |
| 346.82 | 2.00 | 2.00 |
| 443.94 | 2.00 | 2.00 |
| 389.84 | 3.49 | 3.49 |