Basic Information
ID: ALA1291826
Type: Binding
Description: Inhibition of COX-1 in rabbit peripheral venous blood assessed as formation of 12-hydroxyheptadecatrienoic acid after 24 hrs by HPLC in presence of calcium ionophore A23187
Organism: Oryctolagus cuniculus
Tissue: Venous blood
Activity Charts
Bioactivity
Activity Types for Assay ALA1291826
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.58 | 4.13 | 4.13 |
| 345.34 | 1.73 | 1.73 |
| 299.35 | 2.58 | 2.58 |
| 317.34 | 2.72 | 2.72 |
| 333.80 | 3.24 | 3.24 |
| 313.38 | 2.89 | 2.89 |
| 333.80 | 3.24 | 3.24 |
| 378.25 | 3.35 | 3.35 |
| 344.35 | 2.49 | 2.49 |
| 300.34 | 1.83 | 1.83 |
| 318.33 | 1.97 | 1.97 |
| 334.78 | 2.48 | 2.48 |
| 314.37 | 2.14 | 2.14 |
| 334.78 | 2.48 | 2.48 |
| 379.24 | 2.59 | 2.59 |
| 320.76 | 3.25 | 3.25 |