Basic Information
ID: ALA1292492
Type: Functional
Description: Antagonist activity at human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells assessed as inhibition of (S)-glutamate/glycine-stimulated excitotoxicity treated 30 mins before (S)-glutamate/glycine challenge measured after 4 hrs by LDH release assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1292492
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.45 | 3.61 | 3.61 |
| 311.43 | 3.31 | 3.31 |
| 337.46 | 4.01 | 4.01 |