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ID: ALA1613763
Type: Functional
Description: PUBCHEM_BIOASSAY: Luminescent dose response cell-based high throughput screening assay for inhibitors of the Janus kinase 2 mutant JAK2V617F. (Class of assay: confirmatory) [Related pubchem assays: 1446 (Primary screen.), 1521 (Confirmation assay.), 1486 (Counter screen.)]
Bioactivity
Activity Types for Assay ALA1613763
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
253.27 | 0.83 | 0.83 |
322.36 | 2.75 | 2.75 |
240.44 | 2.06 | 2.06 |
245.19 | -3.46 | -3.46 |
358.38 | 2.06 | 2.06 |
282.30 | 3.10 | 3.10 |
200.24 | 2.57 | 2.57 |
174.09 | -1.10 | -1.10 |
206.25 | 2.39 | 2.39 |
442.52 | 5.28 | 5.28 |
442.97 | 4.43 | 4.43 |
270.76 | 2.02 | 2.02 |
473.23 | 4.43 | 4.43 |
373.66 | 3.25 | 3.25 |
289.67 | 3.49 | 3.49 |
293.37 | 2.71 | 2.71 |
356.81 | 4.21 | 4.21 |
334.33 | 0.08 | 0.08 |
327.81 | 2.60 | 2.60 |
519.58 | 4.06 | 4.06 |
330.39 | 4.06 | 4.06 |
423.54 | 3.96 | 3.96 |
246.22 | 2.75 | 2.75 |
249.71 | 2.24 | 2.24 |
423.54 | 3.96 | 3.96 |
346.34 | 2.19 | 2.19 |
253.77 | 3.84 | 3.84 |
353.46 | 3.77 | 3.77 |
278.23 | 3.82 | 3.82 |
355.44 | 4.20 | 4.20 |
273.76 | 3.77 | 3.77 |
368.39 | 3.18 | 3.18 |
329.21 | 3.14 | 3.14 |
346.65 | 4.03 | 4.03 |
389.46 | 3.57 | 3.57 |
343.81 | 3.74 | 3.74 |
285.74 | 3.09 | 3.09 |
280.33 | 3.77 | 3.77 |
319.67 | 2.09 | 2.09 |
323.40 | 2.72 | 2.72 |
374.19 | 3.90 | 3.90 |
328.73 | 2.48 | 2.48 |
301.78 | 1.72 | 1.72 |
355.44 | 1.48 | 1.48 |
292.24 | 2.16 | 2.16 |
263.73 | 2.55 | 2.55 |
457.55 | 4.16 | 4.16 |
312.38 | 1.57 | 1.57 |
339.44 | 3.23 | 3.23 |
395.46 | 3.49 | 3.49 |
279.73 | 2.33 | 2.33 |
352.32 | 0.22 | 0.22 |
426.49 | 2.90 | 2.90 |
457.55 | 4.16 | 4.16 |
388.25 | 3.92 | 3.92 |
285.13 | 2.85 | 2.85 |
401.96 | 4.95 | 4.95 |
262.70 | 2.68 | 2.68 |
311.78 | 3.66 | 3.66 |
279.72 | 3.79 | 3.79 |
275.31 | 2.99 | 2.99 |
398.39 | 2.01 | 2.01 |
246.74 | 1.88 | 1.88 |
293.33 | 4.50 | 4.50 |
288.31 | 3.02 | 3.02 |
240.65 | -0.01 | -0.01 |
401.48 | 3.56 | 3.56 |
326.40 | 4.35 | 4.35 |
365.01 | 4.22 | 4.22 |
265.70 | 1.94 | 1.94 |
264.80 | 3.54 | 3.54 |
380.44 | 4.27 | 4.27 |
291.78 | 3.35 | 3.35 |
382.41 | 4.01 | 4.01 |
338.46 | 5.31 | 5.31 |
345.49 | 4.54 | 4.54 |
333.56 | 3.02 | 3.02 |
461.52 | 3.99 | 3.99 |
346.83 | 3.47 | 3.47 |
324.43 | 1.96 | 1.96 |
334.33 | 3.37 | 3.37 |
358.47 | 3.70 | 3.70 |
401.96 | 4.95 | 4.95 |
289.33 | 4.14 | 4.14 |
317.10 | 2.50 | 2.50 |
323.37 | 2.60 | 2.60 |
344.42 | 3.33 | 3.33 |
334.32 | 1.93 | 1.93 |
375.90 | 3.38 | 3.38 |
310.26 | 2.16 | 2.16 |
264.28 | 3.76 | 3.76 |
305.83 | 4.63 | 4.63 |
250.37 | 2.47 | 2.47 |
311.36 | 4.01 | 4.01 |
357.35 | 3.75 | 3.75 |
271.32 | 3.03 | 3.03 |
265.27 | 3.26 | 3.26 |
316.81 | 3.42 | 3.42 |
362.81 | 2.99 | 2.99 |
280.78 | 2.57 | 2.57 |
322.22 | 5.66 | 5.66 |
335.64 | 3.57 | 3.57 |
301.20 | 2.92 | 2.92 |
344.37 | 3.80 | 3.80 |
409.31 | 3.72 | 3.72 |
385.47 | 3.82 | 3.82 |
479.49 | 2.59 | 2.59 |
323.35 | 2.64 | 2.64 |