Basic Information
ID: ALA1613775
Type: Functional
Description: PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771, AID488772]
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA1613775
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.18 | 4.50 | 4.50 |
| 391.56 | 6.86 | 6.86 |
| 252.27 | 1.77 | 1.77 |
| 168.15 | 1.22 | 1.22 |
| 414.53 | 3.37 | 3.37 |
| 169.18 | 0.09 | 0.09 |
| 211.26 | 1.13 | 1.13 |
| 300.44 | 5.60 | 5.60 |
| 393.47 | 4.51 | 4.51 |
| 305.21 | 1.93 | 1.93 |
| 254.24 | 2.87 | 2.87 |
| 211.22 | 0.44 | 0.44 |
| 276.38 | 1.96 | 1.96 |
| 184.96 | -0.09 | -0.09 |
| 267.33 | 2.85 | 2.85 |
| 375.87 | 4.43 | 4.43 |
| 392.44 | 1.62 | 1.62 |
| 336.33 | -0.13 | -0.13 |
| 348.36 | 2.08 | 2.08 |
| 130.25 | 1.88 | 1.88 |
| 494.01 | 3.64 | 3.64 |
| 192.26 | 1.10 | 1.10 |
| 1202.63 | ||
| 396.45 | 4.55 | 4.55 |
| 204.23 | 0.83 | 0.83 |
| 414.55 | 1.86 | 1.86 |
| 300.05 | ||
| 304.22 | 3.38 | 3.38 |
| 348.49 | 6.29 | 6.29 |
| 562.67 | 7.50 | 7.50 |
| 211.26 | 1.08 | 1.08 |
| 371.25 | ||
| 300.44 | 5.60 | 5.60 |
| 399.44 | 2.87 | 2.87 |
| 242.27 | 2.75 | 2.75 |
| 325.54 | 5.13 | 5.13 |
| 356.42 | 4.37 | 4.37 |
| 253.27 | 0.83 | 0.83 |
| 285.69 | 2.77 | 2.77 |
| 305.76 | 2.73 | 2.73 |
| 77.15 | -0.13 | -0.13 |
| 339.39 | 3.86 | 3.86 |
| 283.33 | 2.56 | 2.56 |
| 246.31 | 4.49 | 4.49 |
| 396.45 | 0.59 | 0.59 |
| 284.43 | 4.24 | 4.24 |
| 277.41 | 4.21 | 4.21 |
| 183.21 | 0.35 | 0.35 |
| 320.43 | 5.17 | 5.17 |
| 215.03 | 3.10 | 3.10 |
| 221.30 | 3.15 | 3.15 |
| 387.48 | 0.72 | 0.72 |
| 189.13 | -2.46 | -2.46 |
| 211.22 | 0.44 | 0.44 |
| 110.11 | 1.10 | 1.10 |
| 179.22 | 0.91 | 0.91 |
| 330.78 | 1.79 | 1.79 |
| 187.17 | 0.23 | 0.23 |
| 167.21 | 0.86 | 0.86 |
| 167.21 | 0.64 | 0.64 |
| 311.38 | 3.34 | 3.34 |
| 247.32 | 2.39 | 2.39 |
| 329.83 | 3.93 | 3.93 |
| 516.55 | 5.40 | 5.40 |
| 361.83 | 3.55 | 3.55 |
| 145.11 | -1.11 | -1.11 |
| 281.76 | 2.60 | 2.60 |
| 270.24 | 1.89 | 1.89 |
| 292.14 | 1.76 | 1.76 |
| 312.80 | 3.38 | 3.38 |
| 338.21 | 4.10 | 4.10 |
| 211.22 | -0.50 | -0.50 |
| 592.78 | 6.54 | 6.54 |
| 334.42 | 2.38 | 2.38 |
| 274.27 | 2.32 | 2.32 |
| 349.39 | 0.18 | 0.18 |
| 428.44 | 2.54 | 2.54 |
| 399.62 | 4.23 | 4.23 |
| 327.18 | 4.09 | 4.09 |
| 518.56 | 6.38 | 6.38 |
| 258.06 | 2.95 | 2.95 |
| 204.23 | 1.12 | 1.12 |
| 255.36 | 3.72 | 3.72 |
| 275.35 | 1.81 | 1.81 |
| 294.31 | 2.32 | 2.32 |
| 297.27 | 2.30 | 2.30 |
| 308.34 | 2.36 | 2.36 |
| 152.29 | 0.29 | 0.29 |
| 296.55 | 3.62 | 3.62 |
| 291.44 | 4.56 | 4.56 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 205.22 | 0.72 | 0.72 |
| 463.34 | 3.94 | 3.94 |
| 290.41 | 3.79 | 3.79 |
| 318.24 | 1.69 | 1.69 |
| 436.62 | 7.51 | 7.51 |
| 448.44 | 1.65 | 1.65 |
| 228.25 | 2.97 | 2.97 |
| 214.18 | 0.16 | 0.16 |
| 244.25 | 2.68 | 2.68 |
| 249.31 | 1.94 | 1.94 |
| 197.19 | 0.05 | 0.05 |
| 326.44 | 3.52 | 3.52 |
| 244.38 | 3.15 | 3.15 |
| 520.95 | 5.01 | 5.01 |
| 184.20 | 2.13 | 2.13 |
| 236.23 | 1.56 | 1.56 |
| 186.17 | 1.53 | 1.53 |
| 282.39 | 4.42 | 4.42 |
| 218.30 | 1.76 | 1.76 |
| 353.47 | 1.94 | 1.94 |
| 264.33 | 3.25 | 3.25 |
| 221.21 | 0.57 | 0.57 |
| 213.24 | 3.51 | 3.51 |
| 376.39 | 0.53 | 0.53 |
| 302.37 | 3.57 | 3.57 |
| 166.24 | 1.98 | 1.98 |
| 650.76 | 3.93 | 3.93 |
| 293.37 | 3.41 | 3.41 |
| 380.50 | 3.12 | 3.12 |
| 497.50 | 1.02 | 1.02 |
| 213.19 | -0.24 | -0.24 |
| 361.53 | 4.05 | 4.05 |
| 359.73 | 2.43 | 2.43 |
| 335.67 | 3.04 | 3.04 |
| 395.26 | 2.63 | 2.63 |
| 304.35 | 3.84 | 3.84 |
| 256.26 | 2.70 | 2.70 |
| 312.48 | 5.02 | 5.02 |
| 262.22 | 0.84 | 0.84 |
| 304.25 | 1.19 | 1.19 |
| 181.24 | 0.68 | 0.68 |
| 139.18 | -0.78 | -0.78 |
| 168.15 | 0.72 | 0.72 |
| 220.23 | 0.83 | 0.83 |
| 91.07 | -1.04 | -1.04 |
| 361.53 | 5.33 | 5.33 |
| 289.76 | 3.03 | 3.03 |
| 573.64 | ||
| 510.83 | 5.45 | 5.45 |
| 279.10 | -0.20 | -0.20 |
| 305.29 | 3.12 | 3.12 |
| 454.52 | -0.64 | -0.64 |
| 169.18 | 0.09 | 0.09 |
| 476.79 | 4.68 | 4.68 |
| 295.38 | 3.63 | 3.63 |
| 434.28 | 6.35 | 6.35 |
| 394.44 | 0.62 | 0.62 |
| 191.19 | 1.50 | 1.50 |
| 216.32 | 4.18 | 4.18 |
| 376.91 | 3.62 | 3.62 |
| 310.40 | 1.73 | 1.73 |
| 416.28 | 2.43 | 2.43 |
| 324.83 | 2.48 | 2.48 |
| 417.63 | 6.79 | 6.79 |
| 304.32 | 2.98 | 2.98 |
| 360.45 | 1.99 | 1.99 |
| 346.34 | 2.18 | 2.18 |
| 370.48 | 2.53 | 2.53 |
| 277.27 | 1.15 | 1.15 |
| 308.34 | 2.88 | 2.88 |
| 241.25 | -1.70 | -1.70 |
| 207.25 | 1.81 | 1.81 |
| 249.34 | 2.80 | 2.80 |
| 471.56 | 2.88 | 2.88 |
| 464.86 | 0.26 | 0.26 |
| 248.32 | 2.76 | 2.76 |
| 179.14 | -1.41 | -1.41 |
| 332.85 | 1.58 | 1.58 |
| 220.25 | 1.29 | 1.29 |
| 264.22 | 0.41 | 0.41 |
| 320.05 | 5.93 | 5.93 |
| 384.31 | 1.45 | 1.45 |
| 382.39 | 2.73 | 2.73 |
| 455.47 | -0.62 | -0.62 |
| 316.47 | 4.18 | 4.18 |
| 183.21 | 0.35 | 0.35 |
| 357.16 | ||
| 611.74 | 2.72 | 2.72 |
| 193.16 | 1.66 | 1.66 |
| 371.46 | 2.64 | 2.64 |
| 331.46 | 5.32 | 5.32 |
| 399.41 | -0.61 | -0.61 |
| 208.26 | 1.16 | 1.16 |
| 257.25 | -1.76 | -1.76 |
| 774.17 | 3.85 | 3.85 |
| 211.26 | 1.13 | 1.13 |
| 267.36 | 3.13 | 3.13 |
| 170.17 | -0.39 | -0.39 |
| 471.55 | -0.73 | -0.73 |
| 239.31 | 1.91 | 1.91 |
| 339.44 | 1.92 | 1.92 |
| 238.20 | 0.70 | 0.70 |
| 1031.00 | ||
| 181.22 | 0.28 | 0.28 |
| 175.14 | 2.19 | 2.19 |
| 126.12 | -1.07 | -1.07 |
| 212.63 | 2.01 | 2.01 |
| 235.34 | 2.95 | 2.95 |
| 168.15 | 1.22 | 1.22 |
| 523.63 | 5.53 | 5.53 |
| 373.39 | 1.95 | 1.95 |
| 437.19 | 3.21 | 3.21 |
| 650.78 | 3.28 | 3.28 |
| 183.21 | 0.48 | 0.48 |
| 184.19 | 0.43 | 0.43 |
| 211.22 | 0.14 | 0.14 |
| 277.35 | 0.83 | 0.83 |
| 195.22 | 0.74 | 0.74 |
| 404.43 | 2.96 | 2.96 |
| 276.61 | 3.51 | 3.51 |
| 211.20 | 1.35 | 1.35 |
| 198.23 | 1.87 | 1.87 |
| 392.18 | ||
| 261.92 | ||
| 268.23 | 0.97 | 0.97 |
| 456.50 | 1.53 | 1.53 |
| 327.38 | 1.30 | 1.30 |
| 554.59 | -1.20 | -1.20 |
| 610.85 | 5.21 | 5.21 |
| 226.23 | -0.05 | -0.05 |
| 393.28 | 6.20 | 6.20 |
| 810.99 | 3.99 | 3.99 |
| 355.50 | 4.51 | 4.51 |
| 207.24 | 0.19 | 0.19 |
| 201.22 | 1.64 | 1.64 |
| 343.20 | 1.52 | 1.52 |
| 249.36 | 2.74 | 2.74 |
| 261.35 | 2.74 | 2.74 |
| 745.42 | -2.57 | -2.57 |
| 606.44 | 2.49 | 2.49 |
| 616.84 | 5.75 | 5.75 |
| 532.56 | -1.89 | -1.89 |