Basic Information
ID: ALA1613805
Type: Functional
Description: PUBCHEM_BIOASSAY: Cytometry Cell-Based qHTS for Inhibitors of the mTORC1 Signaling Pathway in MEF cells. (Class of assay: confirmatory)
Organism: Homo sapiens
Cell type: MEF
Activity Charts
Bioactivity
Activity Types for Assay ALA1613805
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.18 | 4.50 | 4.50 |
| 383.41 | 1.78 | 1.78 |
| 357.79 | 3.93 | 3.93 |
| 280.42 | 3.88 | 3.88 |
| 391.56 | 6.86 | 6.86 |
| 168.15 | 1.22 | 1.22 |
| 314.86 | 4.53 | 4.53 |
| 231.09 | 1.81 | 1.81 |
| 407.51 | 4.95 | 4.95 |
| 211.26 | 1.13 | 1.13 |
| 309.33 | 4.44 | 4.44 |
| 263.38 | 3.83 | 3.83 |
| 399.97 | 5.97 | 5.97 |
| 393.47 | 4.51 | 4.51 |
| 394.42 | 3.70 | 3.70 |
| 196.20 | 0.64 | 0.64 |
| 214.22 | 0.73 | 0.73 |
| 284.36 | 2.95 | 2.95 |
| 211.22 | 0.44 | 0.44 |
| 375.87 | 4.43 | 4.43 |
| 361.53 | 4.84 | 4.84 |
| 444.49 | -0.14 | -0.14 |
| 153.18 | 0.60 | 0.60 |
| 348.36 | 2.08 | 2.08 |
| 301.33 | 3.03 | 3.03 |
| 370.59 | 5.89 | 5.89 |
| 318.87 | 4.89 | 4.89 |
| 266.39 | 3.53 | 3.53 |
| 1202.63 | ||
| 329.37 | 3.33 | 3.33 |
| 204.23 | 0.83 | 0.83 |
| 473.59 | 6.08 | 6.08 |
| 371.52 | 6.00 | 6.00 |
| 654.61 | 3.19 | 3.19 |
| 853.92 | 3.74 | 3.74 |
| 319.45 | 3.94 | 3.94 |
| 414.41 | 2.41 | 2.41 |
| 125.17 | -0.08 | -0.08 |
| 477.58 | 5.48 | 5.48 |
| 287.41 | 4.70 | 4.70 |
| 348.49 | 6.29 | 6.29 |
| 238.29 | 3.12 | 3.12 |
| 110.11 | 1.10 | 1.10 |
| 300.44 | 5.60 | 5.60 |
| 394.86 | 5.13 | 5.13 |
| 283.26 | 3.06 | 3.06 |
| 409.42 | 4.79 | 4.79 |
| 354.45 | 2.65 | 2.65 |
| 242.27 | 2.75 | 2.75 |
| 284.43 | 4.24 | 4.24 |
| 497.60 | 5.03 | 5.03 |
| 403.98 | 3.94 | 3.94 |
| 352.43 | 5.26 | 5.26 |
| 253.27 | 0.83 | 0.83 |
| 285.69 | 2.77 | 2.77 |
| 360.35 | 4.85 | 4.85 |
| 471.69 | 6.45 | 6.45 |
| 212.30 | 2.25 | 2.25 |
| 283.33 | 2.56 | 2.56 |
| 246.31 | 4.49 | 4.49 |
| 450.57 | 5.32 | 5.32 |
| 277.41 | 4.17 | 4.17 |
| 341.45 | 3.24 | 3.24 |
| 645.32 | 6.94 | 6.94 |
| 284.43 | 4.24 | 4.24 |
| 277.41 | 4.21 | 4.21 |
| 275.40 | 4.55 | 4.55 |
| 360.84 | 4.68 | 4.68 |
| 183.21 | 0.35 | 0.35 |
| 320.43 | 5.17 | 5.17 |
| 215.03 | 3.10 | 3.10 |
| 451.48 | 1.72 | 1.72 |
| 417.55 | 4.18 | 4.18 |
| 110.11 | 1.10 | 1.10 |
| 353.51 | 4.66 | 4.66 |
| 414.59 | 5.04 | 5.04 |
| 406.48 | 3.74 | 3.74 |
| 437.53 | 4.31 | 4.31 |
| 373.95 | 4.58 | 4.58 |
| 550.76 | 5.98 | 5.98 |
| 347.86 | 4.47 | 4.47 |
| 472.09 | 8.01 | 8.01 |
| 542.42 | 4.16 | 4.16 |
| 395.47 | 4.23 | 4.23 |
| 311.38 | 3.34 | 3.34 |
| 374.28 | 4.04 | 4.04 |
| 329.83 | 3.93 | 3.93 |
| 295.38 | 3.27 | 3.27 |
| 243.22 | -2.56 | -2.56 |
| 179.31 | 2.69 | 2.69 |
| 306.24 | 5.18 | 5.18 |
| 180.21 | 2.78 | 2.78 |
| 582.79 | 6.80 | 6.80 |
| 340.49 | 4.83 | 4.83 |
| 329.44 | 3.26 | 3.26 |
| 477.05 | 5.09 | 5.09 |
| 312.80 | 3.38 | 3.38 |
| 475.58 | 5.31 | 5.31 |
| 370.46 | 5.59 | 5.59 |
| 495.64 | 5.27 | 5.27 |
| 302.41 | 3.62 | 3.62 |
| 274.18 | ||
| 480.65 | 4.94 | 4.94 |
| 327.18 | 4.09 | 4.09 |
| 518.56 | 6.38 | 6.38 |
| 434.53 | 4.60 | 4.60 |
| 390.52 | 3.95 | 3.95 |
| 294.31 | 2.32 | 2.32 |
| 308.34 | 2.36 | 2.36 |
| 322.36 | 2.75 | 2.75 |
| 340.85 | 4.30 | 4.30 |
| 369.34 | 4.40 | 4.40 |
| 414.51 | 3.57 | 3.57 |
| 296.55 | 3.62 | 3.62 |
| 291.44 | 4.56 | 4.56 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 344.91 | 4.34 | 4.34 |
| 290.41 | 3.79 | 3.79 |
| 318.24 | 1.69 | 1.69 |
| 436.62 | 7.51 | 7.51 |
| 228.25 | 2.97 | 2.97 |
| 325.45 | 3.77 | 3.77 |
| 339.48 | 4.02 | 4.02 |
| 244.25 | 2.68 | 2.68 |
| 304.31 | 3.37 | 3.37 |
| 382.89 | 4.89 | 4.89 |
| 469.67 | 7.22 | 7.22 |
| 251.29 | 2.00 | 2.00 |
| 326.44 | 3.52 | 3.52 |
| 520.95 | 5.01 | 5.01 |
| 447.36 | 4.83 | 4.83 |
| 282.39 | 4.42 | 4.42 |
| 218.30 | 1.76 | 1.76 |
| 417.63 | 7.05 | 7.05 |
| 381.55 | 5.16 | 5.16 |
| 287.32 | 3.10 | 3.10 |
| 264.33 | 3.25 | 3.25 |
| 302.37 | 3.57 | 3.57 |
| 303.41 | 4.89 | 4.89 |
| 650.76 | 3.93 | 3.93 |
| 293.37 | 3.41 | 3.41 |
| 356.56 | 4.40 | 4.40 |
| 313.79 | 3.43 | 3.43 |
| 256.69 | 3.66 | 3.66 |
| 307.35 | 3.30 | 3.30 |
| 291.38 | 1.22 | 1.22 |
| 380.50 | 3.12 | 3.12 |
| 497.50 | 1.02 | 1.02 |
| 356.51 | 3.25 | 3.25 |
| 284.31 | 2.90 | 2.90 |
| 346.47 | 2.67 | 2.67 |
| 361.53 | 4.05 | 4.05 |
| 456.68 | 6.17 | 6.17 |
| 317.43 | 3.24 | 3.24 |
| 212.21 | 1.31 | 1.31 |
| 604.70 | 3.54 | 3.54 |
| 277.28 | 4.42 | 4.42 |
| 256.26 | 2.70 | 2.70 |
| 392.50 | 3.41 | 3.41 |
| 292.21 | 4.79 | 4.79 |
| 220.23 | 0.83 | 0.83 |
| 324.44 | 3.60 | 3.60 |
| 356.18 | 5.18 | 5.18 |
| 385.90 | 3.93 | 3.93 |
| 289.76 | 3.03 | 3.03 |
| 406.50 | 3.21 | 3.21 |
| 592.69 | 2.88 | 2.88 |
| 279.10 | -0.20 | -0.20 |
| 337.42 | 4.41 | 4.41 |
| 310.44 | 5.95 | 5.95 |
| 395.42 | 2.53 | 2.53 |
| 461.56 | 5.86 | 5.86 |
| 425.92 | 3.35 | 3.35 |
| 478.55 | 5.18 | 5.18 |
| 284.77 | 1.73 | 1.73 |
| 130.08 | -0.80 | -0.80 |
| 307.10 | -1.06 | -1.06 |
| 476.79 | 4.68 | 4.68 |
| 295.38 | 3.63 | 3.63 |
| 451.68 | 5.28 | 5.28 |
| 426.52 | 4.60 | 4.60 |
| 327.12 | 3.86 | 3.86 |
| 396.83 | 3.76 | 3.76 |
| 276.68 | 3.50 | 3.50 |
| 481.68 | 6.23 | 6.23 |
| 384.26 | 3.96 | 3.96 |
| 479.53 | 3.68 | 3.68 |
| 310.40 | 1.73 | 1.73 |
| 416.28 | 2.43 | 2.43 |
| 417.63 | 6.79 | 6.79 |
| 244.21 | -3.17 | -3.17 |
| 611.74 | 6.48 | 6.48 |
| 147.27 | 1.30 | 1.30 |
| 395.54 | 4.55 | 4.55 |
| 241.25 | 1.91 | 1.91 |
| 218.21 | 1.57 | 1.57 |
| 343.43 | 4.69 | 4.69 |
| 207.25 | 1.81 | 1.81 |
| 360.37 | 2.57 | 2.57 |
| 248.32 | 2.76 | 2.76 |
| 343.90 | 5.10 | 5.10 |
| 264.13 | 2.99 | 2.99 |
| 264.22 | 0.41 | 0.41 |
| 384.31 | 1.45 | 1.45 |
| 376.58 | 5.66 | 5.66 |
| 316.47 | 4.18 | 4.18 |
| 317.82 | 3.68 | 3.68 |
| 496.68 | 3.80 | 3.80 |
| 490.65 | 3.87 | 3.87 |
| 257.27 | 1.95 | 1.95 |
| 361.53 | 5.53 | 5.53 |
| 193.16 | 1.66 | 1.66 |
| 371.46 | 2.64 | 2.64 |
| 331.46 | 5.32 | 5.32 |
| 401.50 | 4.22 | 4.22 |
| 257.25 | -1.76 | -1.76 |
| 603.76 | 4.11 | 4.11 |
| 211.26 | 1.13 | 1.13 |
| 309.33 | 4.44 | 4.44 |
| 269.34 | 2.72 | 2.72 |
| 322.50 | 4.39 | 4.39 |
| 652.26 | 10.29 | 10.29 |
| 244.23 | 1.82 | 1.82 |
| 181.22 | 0.28 | 0.28 |
| 175.14 | 2.19 | 2.19 |
| 286.40 | 3.70 | 3.70 |
| 555.66 | 4.26 | 4.26 |
| 235.34 | 2.95 | 2.95 |
| 349.57 | ||
| 523.63 | 5.53 | 5.53 |
| 349.40 | 3.65 | 3.65 |
| 296.43 | 4.33 | 4.33 |
| 429.60 | 5.41 | 5.41 |
| 325.45 | 3.14 | 3.14 |
| 650.78 | 3.28 | 3.28 |
| 183.21 | 0.48 | 0.48 |
| 522.61 | 2.97 | 2.97 |
| 315.87 | 5.19 | 5.19 |
| 404.43 | 2.96 | 2.96 |
| 366.46 | 4.15 | 4.15 |
| 211.20 | 1.35 | 1.35 |
| 327.43 | 5.74 | 5.74 |
| 491.65 | 5.96 | 5.96 |
| 198.23 | 1.87 | 1.87 |
| 392.55 | 5.74 | 5.74 |
| 824.97 | 3.52 | 3.52 |
| 481.48 | 3.98 | 3.98 |
| 225.20 | -1.63 | -1.63 |
| 226.23 | -0.05 | -0.05 |
| 393.28 | 6.20 | 6.20 |
| 810.99 | 3.99 | 3.99 |
| 588.56 | 1.69 | 1.69 |
| 415.49 | 3.84 | 3.84 |
| 301.52 | 4.15 | 4.15 |
| 201.22 | 1.64 | 1.64 |
| 390.57 | 3.68 | 3.68 |
| 419.35 | 3.74 | 3.74 |
| 343.20 | 1.52 | 1.52 |
| 508.45 | 5.68 | 5.68 |
| 280.36 | 2.11 | 2.11 |
| 310.46 | 5.07 | 5.07 |
| 375.17 | -0.39 | -0.39 |
| 466.67 | 5.22 | 5.22 |
| 220.23 | 4.43 | 4.43 |
| 314.21 | 3.78 | 3.78 |
| 616.84 | 5.75 | 5.75 |
| 322.45 | 4.00 | 4.00 |
| 392.50 | 2.39 | 2.39 |
| 875.11 | 5.60 | 5.60 |