Basic Information
ID: ALA1613814
Type: Binding
Description: PUBCHEM_BIOASSAY: uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2014, AID2028, AID435011, AID435018, AID449744, AID449751, AID449752]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1613814
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.51 | 4.42 | 4.42 |
| 255.36 | 2.70 | 2.70 |
| 412.30 | 2.41 | 2.41 |
| 412.30 | 2.51 | 2.51 |
| 372.25 | 1.76 | 1.76 |
| 523.06 | 2.78 | 2.78 |
| 511.45 | 5.25 | 5.25 |
| 415.50 | 3.12 | 3.12 |
| 389.52 | 2.06 | 2.06 |
| 437.50 | 3.21 | 3.21 |
| 435.57 | 3.67 | 3.67 |
| 381.40 | 3.66 | 3.66 |
| 378.48 | 3.09 | 3.09 |
| 347.43 | 3.25 | 3.25 |
| 477.54 | 3.21 | 3.21 |
| 431.31 | 2.08 | 2.08 |
| 378.44 | 2.52 | 2.52 |
| 354.31 | 2.76 | 2.76 |
| 396.47 | 3.23 | 3.23 |
| 499.48 | 4.86 | 4.86 |
| 455.35 | 3.10 | 3.10 |
| 313.35 | 3.56 | 3.56 |
| 427.25 | 2.36 | 2.36 |
| 441.53 | 3.88 | 3.88 |
| 397.44 | 4.13 | 4.13 |
| 453.49 | 3.93 | 3.93 |
| 406.31 | 1.67 | 1.67 |
| 516.38 | 4.02 | 4.02 |
| 292.18 | 2.17 | 2.17 |
| 354.39 | 4.11 | 4.11 |
| 416.32 | 4.35 | 4.35 |
| 300.31 | 3.12 | 3.12 |
| 432.50 | 1.22 | 1.22 |
| 370.19 | 1.77 | 1.77 |
| 293.34 | 1.70 | 1.70 |
| 301.77 | 4.05 | 4.05 |
| 359.16 | 2.96 | 2.96 |
| 485.50 | 3.80 | 3.80 |
| 327.17 | 1.08 | 1.08 |
| 404.25 | 1.43 | 1.43 |
| 381.30 | 2.69 | 2.69 |
| 395.48 | 2.77 | 2.77 |
| 315.35 | 3.80 | 3.80 |
| 246.27 | 0.62 | 0.62 |
| 476.60 | 0.30 | 0.30 |
| 443.37 | 2.12 | 2.12 |
| 557.26 | 5.32 | 5.32 |
| 510.46 | 2.87 | 2.87 |
| 248.29 | 3.49 | 3.49 |
| 356.37 | -0.72 | -0.72 |
| 361.49 | 2.09 | 2.09 |
| 388.47 | 2.64 | 2.64 |
| 268.32 | 2.87 | 2.87 |
| 377.22 | 1.35 | 1.35 |
| 398.28 | 3.30 | 3.30 |
| 527.62 | 6.02 | 6.02 |
| 388.49 | 2.83 | 2.83 |
| 361.27 | 2.74 | 2.74 |
| 337.20 | 2.99 | 2.99 |
| 354.41 | 3.69 | 3.69 |
| 371.42 | 3.48 | 3.48 |
| 355.42 | 3.15 | 3.15 |
| 326.38 | 3.38 | 3.38 |
| 477.39 | 4.13 | 4.13 |
| 264.21 | 1.39 | 1.39 |
| 378.82 | 1.83 | 1.83 |
| 348.42 | 2.45 | 2.45 |
| 406.80 | 4.20 | 4.20 |
| 297.38 | 4.12 | 4.12 |
| 349.77 | 2.76 | 2.76 |
| 330.22 | 2.21 | 2.21 |
| 411.53 | 4.60 | 4.60 |
| 298.13 | 1.57 | 1.57 |
| 386.47 | 4.08 | 4.08 |
| 438.35 | 3.42 | 3.42 |
| 282.73 | 4.14 | 4.14 |
| 282.73 | 4.14 | 4.14 |
| 395.45 | 3.85 | 3.85 |
| 313.14 | 1.06 | 1.06 |
| 362.26 | 5.12 | 5.12 |
| 374.46 | 2.58 | 2.58 |
| 307.33 | 3.08 | 3.08 |
| 370.19 | 1.77 | 1.77 |
| 456.37 | 2.99 | 2.99 |
| 294.41 | 3.68 | 3.68 |
| 439.54 | 2.17 | 2.17 |
| 353.42 | 2.90 | 2.90 |
| 495.00 | 1.83 | 1.83 |
| 386.54 | 3.19 | 3.19 |
| 264.28 | 1.86 | 1.86 |
| 368.26 | 3.41 | 3.41 |
| 385.24 | 2.32 | 2.32 |
| 369.85 | 2.36 | 2.36 |
| 344.24 | 2.35 | 2.35 |
| 441.48 | 2.21 | 2.21 |
| 386.89 | 5.18 | 5.18 |
| 305.33 | 3.83 | 3.83 |
| 313.40 | 2.64 | 2.64 |
| 388.35 | 3.41 | 3.41 |
| 359.59 | 2.51 | 2.51 |
| 466.93 | 3.12 | 3.12 |
| 507.06 | 3.40 | 3.40 |
| 342.46 | 3.86 | 3.86 |
| 403.52 | 2.90 | 2.90 |
| 403.30 | 3.31 | 3.31 |
| 317.37 | 3.27 | 3.27 |
| 325.17 | -0.17 | -0.17 |
| 337.36 | 4.25 | 4.25 |
| 437.53 | 2.69 | 2.69 |
| 338.86 | 2.75 | 2.75 |
| 455.56 | 3.41 | 3.41 |
| 327.41 | 3.99 | 3.99 |
| 326.14 | 1.56 | 1.56 |
| 383.40 | 1.20 | 1.20 |
| 292.16 | 2.16 | 2.16 |
| 368.42 | 3.43 | 3.43 |
| 291.30 | 2.37 | 2.37 |
| 313.38 | 3.60 | 3.60 |
| 388.34 | 1.89 | 1.89 |
| 374.42 | 2.67 | 2.67 |
| 404.43 | 3.10 | 3.10 |
| 265.31 | 2.19 | 2.19 |
| 349.41 | 2.24 | 2.24 |
| 482.54 | 3.79 | 3.79 |
| 351.45 | 2.35 | 2.35 |
| 303.27 | 1.94 | 1.94 |
| 341.37 | 2.14 | 2.14 |
| 402.52 | 2.97 | 2.97 |
| 363.95 | 2.11 | 2.11 |
| 392.43 | 2.03 | 2.03 |
| 431.54 | 4.99 | 4.99 |
| 541.64 | 6.27 | 6.27 |
| 382.29 | 3.80 | 3.80 |
| 308.29 | 3.92 | 3.92 |
| 454.09 | 1.35 | 1.35 |
| 560.35 | 3.52 | 3.52 |
| 284.31 | 2.78 | 2.78 |
| 305.72 | 3.37 | 3.37 |
| 274.35 | 3.09 | 3.09 |
| 482.35 | 3.98 | 3.98 |
| 419.44 | 3.18 | 3.18 |
| 411.44 | 2.20 | 2.20 |
| 358.31 | 0.11 | 0.11 |
| 354.44 | 3.56 | 3.56 |
| 439.49 | 3.13 | 3.13 |
| 329.27 | 2.47 | 2.47 |
| 378.28 | 3.14 | 3.14 |
| 439.34 | 2.57 | 2.57 |
| 364.25 | 2.75 | 2.75 |
| 347.42 | 2.81 | 2.81 |
| 384.40 | 2.77 | 2.77 |
| 320.35 | 3.98 | 3.98 |
| 482.41 | 4.02 | 4.02 |
| 426.82 | 4.21 | 4.21 |
| 558.27 | 3.96 | 3.96 |
| 413.38 | 3.17 | 3.17 |