Basic Information
ID: ALA1613816
Type: Functional
Description: PUBCHEM_BIOASSAY: Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Synthesized analogs. (Class of assay: confirmatory) [Related pubchem assays: 1796 (Summary AID (NOX1 inhibitors)), 2532 (Dose response (NOX1 inhibitors, HEK/293 cells)), 1792 (Primary Screen (NOX1 inhibitors)), 2545 (Confirmation screen (NOX1 inhibitors, HEK/293 cells)), 2539 (Counterscreen (NOX2, NOX3, NOX4 inhibition)), 2556 (Dose response counterscreen (Xanthine Oxidase inhibitors)), 2538 (Dose response (NOX1 inhibitors)), 2541 (Confirmation screen (NOX1 inhibitors)), 1823 (Counterscreen (luminal))]
Format: BAO_0000219
Organism: Homo sapiens
Target: NADPH oxidase 1(ALA1287628)
Document: ALA1201862
PubChem Source: AID:2664
Activity Charts
Bioactivity
Activity Types for Assay ALA1613816
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 263.37 | 5.36 | 5.36 |
| 261.30 | 2.59 | 2.59 |
| 458.49 | 6.77 | 6.77 |
| 340.40 | 4.57 | 4.57 |
| 231.28 | 2.58 | 2.58 |
| 397.42 | 6.55 | 6.55 |
| 375.45 | 5.43 | 5.43 |
| 255.34 | 4.12 | 4.12 |
| 375.45 | 5.43 | 5.43 |
| 375.45 | 4.75 | 4.75 |
| 293.35 | 4.72 | 4.72 |
| 249.34 | 5.05 | 5.05 |
| 259.33 | 2.99 | 2.99 |
| 362.84 | 4.62 | 4.62 |