Basic Information
ID: ALA1613825
Type: Functional
Description: PUBCHEM_BIOASSAY: Late stage results from the probe development effort to identify inhibitors of NOX1: HEK/293 IC50. (Class of assay: confirmatory) [Related pubchem assays: 1796 (Summary AID (NOX1)), 2752 (Primary screen (NOX1 inhibitors, synthesized analogs set 2)), 2664 (Primary screen (NOX1 inhibitors, synthesized analogs)), 1792 (Primary Screen (NOX1)), 2545 (Confirmation screen (NOX1 inhibitors, HEK/293 cells)), 2539 (Counterscreen (NOX2, NOX3, NOX4 inhibitors)), 2556 (Counterscreen (Xanthine Oxidase inhibitors)), 2538 (Dose response screen (NOX1 inhibitors)), 2541 (Confirmation screen (NOX1 inhibitors)), 1823 (Counterscreen (luminal))]
Format: BAO_0000019
Organism: Homo sapiens
Target: NADPH oxidase 1(ALA1287628)
Document: ALA1201862
PubChem Source: AID:2532
Activity Charts
Bioactivity
Activity Types for Assay ALA1613825
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.40 | 5.12 | 5.12 |
| 267.27 | 4.91 | 4.91 |
| 371.89 | 5.76 | 5.76 |
| 368.89 | 3.98 | 3.98 |
| 361.45 | 4.98 | 4.98 |
| 234.26 | 3.43 | 3.43 |