Basic Information
ID: ALA1613863
Type: Binding
Description: PUBCHEM_BIOASSAY: Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP). (Class of assay: confirmatory) [Related PubChem assays: 1619 (Screening assay (M17LAP inhibitors).), 1445 (Screening assay (M1AAP inhibitors).)]
Organism: Plasmodium falciparum 3D7
Strain: 3D7
Activity Charts
Bioactivity
Activity Types for Assay ALA1613863
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 229.07 | 3.09 | 3.09 |
| 350.37 | 3.23 | 3.23 |
| 367.45 | 3.49 | 3.49 |
| 364.40 | 3.54 | 3.54 |
| 425.49 | 2.68 | 2.68 |
| 378.43 | 3.85 | 3.85 |
| 346.46 | 3.07 | 3.07 |
| 307.40 | 3.00 | 3.00 |
| 429.50 | 3.92 | 3.92 |
| 304.73 | 3.61 | 3.61 |
| 318.33 | 2.98 | 2.98 |
| 505.98 | 5.86 | 5.86 |
| 333.37 | 2.01 | 2.01 |
| 368.46 | 1.48 | 1.48 |
| 499.95 | 5.80 | 5.80 |
| 305.36 | 2.11 | 2.11 |
| 256.13 | 2.52 | 2.52 |
| 399.47 | 4.12 | 4.12 |
| 487.40 | 2.96 | 2.96 |
| 374.65 | 3.33 | 3.33 |
| 426.49 | 4.24 | 4.24 |
| 178.17 | 1.92 | 1.92 |
| 390.47 | 4.07 | 4.07 |
| 382.43 | 1.95 | 1.95 |
| 211.68 | 2.41 | 2.41 |
| 442.49 | 3.75 | 3.75 |
| 356.45 | 3.35 | 3.35 |
| 190.20 | 1.79 | 1.79 |
| 317.37 | 2.11 | 2.11 |
| 395.51 | 4.66 | 4.66 |
| 480.55 | 4.25 | 4.25 |
| 188.23 | 2.40 | 2.40 |
| 491.57 | 5.08 | 5.08 |
| 279.72 | 2.95 | 2.95 |
| 321.43 | 3.31 | 3.31 |
| 313.74 | 2.71 | 2.71 |
| 337.40 | 2.76 | 2.76 |
| 467.58 | 3.98 | 3.98 |
| 394.88 | 3.64 | 3.64 |
| 426.49 | 4.30 | 4.30 |
| 373.48 | 3.45 | 3.45 |
| 321.43 | 3.31 | 3.31 |
| 379.48 | 3.63 | 3.63 |
| 401.54 | 4.26 | 4.26 |
| 390.42 | 1.53 | 1.53 |
| 412.47 | 3.99 | 3.99 |
| 456.52 | 4.25 | 4.25 |
| 308.34 | 3.67 | 3.67 |
| 377.43 | 3.52 | 3.52 |
| 347.37 | 2.63 | 2.63 |
| 413.50 | 4.51 | 4.51 |
| 321.43 | 3.25 | 3.25 |
| 368.36 | 3.37 | 3.37 |
| 349.18 | 3.72 | 3.72 |
| 449.42 | 3.29 | 3.29 |
| 358.46 | 3.88 | 3.88 |
| 375.40 | 3.40 | 3.40 |
| 256.13 | 2.52 | 2.52 |
| 211.68 | 2.41 | 2.41 |
| 289.38 | 3.64 | 3.64 |
| 480.62 | 4.51 | 4.51 |
| 429.27 | 4.00 | 4.00 |
| 434.55 | 5.36 | 5.36 |
| 371.82 | 4.74 | 4.74 |
| 395.48 | 3.58 | 3.58 |
| 440.52 | 4.61 | 4.61 |
| 432.53 | 2.66 | 2.66 |
| 314.17 | 3.60 | 3.60 |
| 461.45 | 3.92 | 3.92 |
| 194.62 | 2.44 | 2.44 |
| 304.38 | 2.23 | 2.23 |
| 351.40 | 4.39 | 4.39 |
| 440.52 | 4.55 | 4.55 |
| 321.36 | 1.23 | 1.23 |
| 524.01 | 4.80 | 4.80 |
| 339.78 | 2.96 | 2.96 |
| 489.92 | 5.40 | 5.40 |
| 205.17 | 1.69 | 1.69 |
| 390.48 | 2.68 | 2.68 |
| 381.44 | 2.56 | 2.56 |
| 529.98 | 5.81 | 5.81 |
| 325.39 | 3.11 | 3.11 |
| 364.85 | 3.67 | 3.67 |
| 382.51 | 2.84 | 2.84 |
| 337.38 | 3.72 | 3.72 |
| 508.01 | 5.19 | 5.19 |
| 329.43 | 3.02 | 3.02 |
| 443.52 | 4.03 | 4.03 |
| 342.36 | 0.79 | 0.79 |
| 308.33 | 2.22 | 2.22 |
| 443.53 | 4.23 | 4.23 |
| 442.49 | 4.00 | 4.00 |
| 378.88 | 3.92 | 3.92 |
| 204.23 | 2.18 | 2.18 |
| 457.55 | 4.41 | 4.41 |
| 210.24 | 2.94 | 2.94 |
| 419.53 | 4.74 | 4.74 |
| 366.45 | 2.90 | 2.90 |
| 341.39 | 2.37 | 2.37 |
| 378.88 | 4.06 | 4.06 |
| 461.52 | 4.37 | 4.37 |
| 220.30 | 1.96 | 1.96 |
| 413.50 | 4.51 | 4.51 |
| 273.33 | 2.85 | 2.85 |
| 378.46 | 4.04 | 4.04 |
| 358.46 | 3.74 | 3.74 |
| 351.50 | 3.01 | 3.01 |
| 413.50 | 4.42 | 4.42 |
| 220.23 | 1.80 | 1.80 |
| 290.71 | 3.68 | 3.68 |
| 331.41 | 3.60 | 3.60 |
| 397.44 | 2.26 | 2.26 |
| 417.53 | 3.90 | 3.90 |
| 338.82 | 3.41 | 3.41 |
| 343.33 | 3.24 | 3.24 |
| 415.49 | 3.73 | 3.73 |
| 262.33 | 3.79 | 3.79 |