Basic Information
ID: ALA1613864
Type: Functional
Description: PUBCHEM_BIOASSAY: Luminescent HTS for small molecule inhibitors of MT1-MMP transcription. (Class of assay: confirmatory) [Related pubchem assays: 620, 773 ]
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1613864
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.21 | 3.25 | 3.25 |
| 194.24 | 2.97 | 2.97 |
| 227.29 | 3.67 | 3.67 |
| 239.32 | 2.86 | 2.86 |
| 237.26 | 2.82 | 2.82 |
| 224.26 | 3.24 | 3.24 |
| 333.39 | 4.18 | 4.18 |
| 223.28 | 4.11 | 4.11 |
| 302.36 | 3.85 | 3.85 |
| 258.71 | 3.54 | 3.54 |
| 292.09 | 3.15 | 3.15 |
| 282.32 | 3.02 | 3.02 |
| 253.26 | 2.81 | 2.81 |
| 289.32 | 2.73 | 2.73 |
| 319.39 | 4.43 | 4.43 |
| 383.50 | 1.56 | 1.56 |
| 342.83 | 3.68 | 3.68 |
| 307.18 | 3.61 | 3.61 |
| 442.49 | 4.30 | 4.30 |
| 279.34 | 4.10 | 4.10 |
| 371.49 | 4.41 | 4.41 |
| 258.71 | 3.05 | 3.05 |
| 272.30 | 2.90 | 2.90 |
| 238.29 | 3.64 | 3.64 |
| 290.75 | 3.79 | 3.79 |
| 269.30 | 3.02 | 3.02 |
| 335.16 | 2.87 | 2.87 |
| 287.71 | 3.36 | 3.36 |
| 318.43 | 3.51 | 3.51 |
| 290.39 | 2.85 | 2.85 |
| 415.30 | 3.60 | 3.60 |
| 284.32 | 2.32 | 2.32 |
| 256.31 | 3.15 | 3.15 |
| 473.47 | 2.58 | 2.58 |
| 260.39 | 4.28 | 4.28 |
| 276.32 | 2.23 | 2.23 |
| 294.29 | 2.03 | 2.03 |
| 329.36 | 3.61 | 3.61 |
| 270.28 | 2.86 | 2.86 |
| 259.26 | 2.47 | 2.47 |
| 247.30 | 3.28 | 3.28 |
| 286.31 | 3.25 | 3.25 |
| 226.30 | 3.55 | 3.55 |
| 355.33 | 4.30 | 4.30 |
| 280.33 | 2.68 | 2.68 |
| 434.54 | 3.89 | 3.89 |
| 269.33 | 3.13 | 3.13 |
| 262.26 | 2.97 | 2.97 |
| 362.47 | 4.64 | 4.64 |
| 260.30 | 1.94 | 1.94 |
| 440.33 | 5.45 | 5.45 |
| 343.38 | 3.91 | 3.91 |
| 330.39 | 2.64 | 2.64 |
| 294.35 | 4.54 | 4.54 |
| 293.35 | 2.37 | 2.37 |
| 315.79 | 4.42 | 4.42 |
| 239.28 | 2.82 | 2.82 |
| 327.43 | 4.12 | 4.12 |
| 279.30 | 2.26 | 2.26 |
| 289.34 | 3.20 | 3.20 |
| 252.32 | 4.20 | 4.20 |
| 369.49 | 4.14 | 4.14 |
| 267.29 | 2.60 | 2.60 |
| 336.44 | 3.29 | 3.29 |
| 434.52 | 4.82 | 4.82 |
| 262.31 | 2.63 | 2.63 |
| 238.25 | 3.08 | 3.08 |
| 332.36 | 2.44 | 2.44 |
| 301.14 | 4.17 | 4.17 |
| 320.35 | 3.06 | 3.06 |
| 402.47 | 2.31 | 2.31 |
| 333.44 | 2.74 | 2.74 |
| 287.75 | 3.29 | 3.29 |
| 265.31 | 3.12 | 3.12 |
| 226.24 | 2.67 | 2.67 |
| 269.34 | 3.06 | 3.06 |
| 259.33 | 3.11 | 3.11 |
| 234.33 | 2.31 | 2.31 |
| 336.83 | 3.69 | 3.69 |
| 320.41 | 3.15 | 3.15 |
| 251.29 | 2.73 | 2.73 |
| 333.89 | 4.05 | 4.05 |
| 285.30 | 2.72 | 2.72 |
| 316.36 | 2.97 | 2.97 |
| 316.38 | 2.80 | 2.80 |
| 320.48 | 2.76 | 2.76 |
| 254.35 | 4.27 | 4.27 |
| 269.34 | 4.18 | 4.18 |
| 274.11 | 1.79 | 1.79 |
| 319.42 | 2.35 | 2.35 |
| 252.32 | 3.59 | 3.59 |
| 395.51 | 5.18 | 5.18 |
| 257.36 | 2.94 | 2.94 |
| 262.26 | 2.96 | 2.96 |
| 268.34 | 3.07 | 3.07 |
| 366.43 | 2.80 | 2.80 |
| 272.30 | 2.67 | 2.67 |
| 360.48 | 3.68 | 3.68 |
| 410.47 | 4.72 | 4.72 |
| 304.40 | 3.20 | 3.20 |
| 279.35 | 2.72 | 2.72 |
| 283.31 | 3.12 | 3.12 |
| 477.03 | 3.74 | 3.74 |
| 246.29 | 2.27 | 2.27 |
| 384.34 | 3.78 | 3.78 |
| 230.29 | 3.42 | 3.42 |
| 224.26 | 3.39 | 3.39 |
| 224.26 | 3.39 | 3.39 |
| 279.34 | 4.14 | 4.14 |
| 236.32 | 4.08 | 4.08 |
| 464.50 | 2.79 | 2.79 |
| 239.28 | 2.97 | 2.97 |
| 336.40 | 2.42 | 2.42 |
| 239.27 | 3.21 | 3.21 |
| 262.31 | 3.80 | 3.80 |
| 273.29 | 3.40 | 3.40 |
| 224.27 | 2.31 | 2.31 |
| 367.49 | 4.16 | 4.16 |
| 388.37 | 2.89 | 2.89 |
| 400.85 | 2.62 | 2.62 |
| 252.36 | 3.41 | 3.41 |
| 274.32 | 2.03 | 2.03 |
| 318.35 | 2.43 | 2.43 |
| 273.38 | 3.53 | 3.53 |
| 283.34 | 2.64 | 2.64 |
| 360.37 | 2.01 | 2.01 |
| 238.29 | 3.69 | 3.69 |
| 398.55 | 5.15 | 5.15 |
| 256.30 | 2.98 | 2.98 |
| 259.26 | 2.85 | 2.85 |
| 301.32 | 1.71 | 1.71 |
| 233.34 | 2.41 | 2.41 |
| 236.27 | 3.71 | 3.71 |
| 402.47 | 3.12 | 3.12 |
| 234.26 | 2.60 | 2.60 |
| 323.22 | 3.12 | 3.12 |
| 294.31 | 3.03 | 3.03 |
| 346.18 | 3.78 | 3.78 |
| 344.44 | 2.77 | 2.77 |
| 301.33 | 3.06 | 3.06 |
| 301.30 | 1.27 | 1.27 |
| 326.38 | 3.33 | 3.33 |
| 224.27 | 2.29 | 2.29 |
| 254.29 | 2.30 | 2.30 |
| 342.46 | 4.22 | 4.22 |
| 426.37 | 4.17 | 4.17 |
| 466.56 | 3.14 | 3.14 |
| 273.29 | 3.86 | 3.86 |
| 215.28 | 2.77 | 2.77 |
| 366.86 | 4.06 | 4.06 |
| 309.13 | 4.85 | 4.85 |
| 353.37 | 4.01 | 4.01 |
| 282.34 | 3.66 | 3.66 |
| 471.92 | 4.43 | 4.43 |
| 354.36 | 2.75 | 2.75 |
| 225.25 | 2.66 | 2.66 |
| 266.37 | 2.39 | 2.39 |
| 253.26 | 2.81 | 2.81 |
| 434.63 | 4.16 | 4.16 |
| 401.51 | 4.56 | 4.56 |
| 307.42 | 3.49 | 3.49 |
| 322.70 | 4.38 | 4.38 |
| 256.26 | 3.40 | 3.40 |
| 321.43 | 3.67 | 3.67 |
| 245.29 | 3.78 | 3.78 |
| 232.29 | 3.81 | 3.81 |
| 329.79 | 2.75 | 2.75 |
| 260.32 | 2.57 | 2.57 |
| 288.27 | 3.00 | 3.00 |
| 342.47 | 3.67 | 3.67 |
| 237.26 | 3.11 | 3.11 |
| 294.35 | 4.40 | 4.40 |
| 345.44 | 4.13 | 4.13 |
| 301.42 | 3.33 | 3.33 |
| 297.36 | 2.89 | 2.89 |
| 255.27 | 2.95 | 2.95 |
| 294.31 | 2.40 | 2.40 |
| 451.58 | 5.10 | 5.10 |
| 308.30 | 2.57 | 2.57 |
| 262.33 | 2.89 | 2.89 |
| 357.41 | 3.39 | 3.39 |
| 326.43 | 3.75 | 3.75 |
| 325.44 | 4.14 | 4.14 |
| 299.87 | 3.86 | 3.86 |
| 280.37 | 3.93 | 3.93 |
| 299.33 | 4.47 | 4.47 |
| 276.36 | 3.23 | 3.23 |
| 229.26 | 2.86 | 2.86 |
| 268.27 | 2.86 | 2.86 |
| 260.31 | 3.10 | 3.10 |
| 325.41 | 3.95 | 3.95 |
| 309.72 | 2.99 | 2.99 |
| 507.03 | 6.71 | 6.71 |
| 285.34 | 4.20 | 4.20 |
| 223.28 | 3.12 | 3.12 |
| 223.24 | 2.80 | 2.80 |
| 419.50 | 5.52 | 5.52 |
| 328.37 | 2.35 | 2.35 |
| 420.97 | 3.18 | 3.18 |
| 391.88 | 3.03 | 3.03 |
| 301.34 | 3.46 | 3.46 |
| 381.29 | 3.67 | 3.67 |
| 266.30 | 3.16 | 3.16 |
| 311.34 | 2.56 | 2.56 |
| 324.81 | 4.15 | 4.15 |
| 268.27 | 2.62 | 2.62 |
| 315.44 | 3.19 | 3.19 |
| 247.34 | 2.86 | 2.86 |
| 261.72 | 2.19 | 2.19 |
| 294.36 | 2.54 | 2.54 |
| 250.26 | 2.95 | 2.95 |
| 368.46 | 3.71 | 3.71 |
| 256.69 | 4.06 | 4.06 |
| 243.31 | 1.69 | 1.69 |
| 404.22 | 2.45 | 2.45 |
| 277.33 | 2.67 | 2.67 |
| 385.45 | 1.90 | 1.90 |
| 259.35 | 3.32 | 3.32 |
| 273.29 | 3.40 | 3.40 |
| 281.32 | 3.48 | 3.48 |
| 260.30 | 1.47 | 1.47 |
| 258.30 | 3.45 | 3.45 |
| 278.40 | 3.73 | 3.73 |
| 406.45 | 1.50 | 1.50 |
| 273.34 | 2.45 | 2.45 |
| 262.26 | 2.15 | 2.15 |
| 322.32 | 3.26 | 3.26 |
| 360.46 | 3.81 | 3.81 |
| 276.32 | 2.23 | 2.23 |
| 231.32 | 2.25 | 2.25 |
| 264.29 | 3.26 | 3.26 |
| 286.36 | 4.25 | 4.25 |
| 331.39 | 3.44 | 3.44 |
| 285.34 | 3.33 | 3.33 |
| 239.27 | 3.81 | 3.81 |
| 262.33 | 3.18 | 3.18 |
| 224.26 | 2.89 | 2.89 |
| 344.47 | 3.41 | 3.41 |
| 442.35 | 4.93 | 4.93 |
| 278.40 | 3.64 | 3.64 |
| 257.25 | 2.71 | 2.71 |
| 328.81 | 2.22 | 2.22 |
| 267.29 | 2.82 | 2.82 |
| 310.35 | 3.40 | 3.40 |
| 474.54 | 3.20 | 3.20 |
| 328.44 | 4.33 | 4.33 |
| 380.51 | 2.50 | 2.50 |
| 249.29 | 2.19 | 2.19 |
| 343.39 | 3.44 | 3.44 |
| 346.43 | 3.22 | 3.22 |
| 307.42 | 2.63 | 2.63 |
| 281.32 | 2.42 | 2.42 |
| 260.25 | 2.72 | 2.72 |
| 250.30 | 2.67 | 2.67 |
| 324.41 | 3.96 | 3.96 |
| 304.33 | 3.47 | 3.47 |
| 279.32 | 1.85 | 1.85 |
| 289.32 | 2.73 | 2.73 |
| 244.29 | 1.85 | 1.85 |
| 293.32 | 4.03 | 4.03 |
| 398.47 | 3.44 | 3.44 |
| 254.29 | 3.39 | 3.39 |
| 269.30 | 3.21 | 3.21 |
| 309.32 | 3.57 | 3.57 |
| 239.27 | 3.69 | 3.69 |
| 339.40 | 4.45 | 4.45 |
| 354.19 | 3.18 | 3.18 |
| 269.30 | 3.21 | 3.21 |
| 328.44 | 4.11 | 4.11 |
| 274.35 | 2.50 | 2.50 |