ID: ALA1613867
Type: Functional
Description: PUBCHEM_BIOASSAY: Dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma). (Class of assay: confirmatory) [Related pubchem assays: 631, 731, 1032, 1300 ]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1613867
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
337.46 | -0.77 | -0.77 |
184.65 | 2.50 | 2.50 |
380.50 | 4.52 | 4.52 |
402.95 | 4.17 | 4.17 |
243.35 | 3.69 | 3.69 |
486.58 | 1.74 | 1.74 |
447.61 | 4.69 | 4.69 |
315.42 | 2.82 | 2.82 |
341.86 | 3.23 | 3.23 |
491.48 | 3.06 | 3.06 |
355.87 | 2.89 | 2.89 |
380.78 | 5.10 | 5.10 |
394.91 | 4.69 | 4.69 |
389.48 | 2.54 | 2.54 |
411.48 | 2.89 | 2.89 |
351.40 | 2.08 | 2.08 |
388.52 | 5.57 | 5.57 |
291.25 | 2.23 | 2.23 |
374.87 | 5.37 | 5.37 |
425.51 | 5.79 | 5.79 |
437.89 | 5.41 | 5.41 |
428.58 | 5.02 | 5.02 |
321.34 | 2.96 | 2.96 |
261.24 | 1.87 | 1.87 |
354.84 | 0.00 | 0.00 |
262.27 | 3.11 | 3.11 |
415.69 | 5.05 | 5.05 |
424.48 | 4.12 | 4.12 |
316.43 | 1.34 | 1.34 |
367.86 | 1.81 | 1.81 |
220.30 | 1.59 | 1.59 |
245.71 | 1.64 | 1.64 |
381.47 | 4.72 | 4.72 |
277.39 | 2.31 | 2.31 |
329.86 | 4.28 | 4.28 |
369.40 | 0.21 | 0.21 |
414.51 | 4.69 | 4.69 |
314.41 | 1.28 | 1.28 |
410.56 | 3.25 | 3.25 |
485.40 | 2.71 | 2.71 |
281.34 | 4.32 | 4.32 |
472.55 | 4.28 | 4.28 |
396.47 | 3.16 | 3.16 |
377.54 | 4.64 | 4.64 |
471.55 | 3.34 | 3.34 |
360.26 | 4.09 | 4.09 |
342.42 | 3.01 | 3.01 |
391.45 | 1.70 | 1.70 |
423.54 | 3.62 | 3.62 |
235.31 | 1.72 | 1.72 |
349.42 | 4.32 | 4.32 |
463.33 | 3.40 | 3.40 |
307.35 | 3.64 | 3.64 |
524.51 | 2.62 | 2.62 |
419.52 | 2.56 | 2.56 |
428.41 | 3.83 | 3.83 |
331.40 | 2.99 | 2.99 |
301.44 | 5.09 | 5.09 |
433.46 | 3.83 | 3.83 |
432.53 | 2.95 | 2.95 |
360.39 | 2.60 | 2.60 |
334.40 | 2.34 | 2.34 |
334.38 | 2.61 | 2.61 |
299.30 | 2.77 | 2.77 |
423.54 | 3.80 | 3.80 |
497.62 | 5.49 | 5.49 |
319.31 | 2.72 | 2.72 |
428.91 | 3.89 | 3.89 |
327.36 | 2.87 | 2.87 |
367.43 | 3.20 | 3.20 |
370.88 | 4.28 | 4.28 |
266.30 | 2.53 | 2.53 |
387.44 | 3.43 | 3.43 |
425.49 | 2.44 | 2.44 |
280.40 | 4.04 | 4.04 |
410.50 | 3.91 | 3.91 |
484.58 | 3.76 | 3.76 |
427.92 | 4.45 | 4.45 |
291.37 | 2.82 | 2.82 |
332.44 | 2.91 | 2.91 |
296.33 | 3.34 | 3.34 |
371.26 | 3.21 | 3.21 |
254.29 | 3.15 | 3.15 |
267.21 | 2.75 | 2.75 |
371.43 | 3.82 | 3.82 |
562.59 | 4.28 | 4.28 |
351.16 | 3.78 | 3.78 |
396.86 | 3.41 | 3.41 |
355.43 | 3.94 | 3.94 |
388.52 | 3.40 | 3.40 |
458.50 | 2.16 | 2.16 |
315.42 | 4.14 | 4.14 |
438.44 | 4.18 | 4.18 |
392.45 | 2.23 | 2.23 |
456.59 | 3.90 | 3.90 |
349.42 | 4.93 | 4.93 |
412.56 | 4.60 | 4.60 |
573.48 | 4.03 | 4.03 |
463.88 | 2.81 | 2.81 |
270.33 | 2.15 | 2.15 |
376.44 | 3.21 | 3.21 |
450.72 | 3.20 | 3.20 |
224.31 | 1.99 | 1.99 |
426.52 | 4.24 | 4.24 |
477.48 | 3.99 | 3.99 |
321.16 | 4.03 | 4.03 |
267.29 | 1.27 | 1.27 |
446.54 | 6.63 | 6.63 |
411.33 | 3.50 | 3.50 |
366.42 | 4.47 | 4.47 |
374.48 | 2.03 | 2.03 |
470.28 | 5.03 | 5.03 |
370.36 | 3.58 | 3.58 |
363.47 | 4.73 | 4.73 |
308.32 | -1.05 | -1.05 |
336.78 | 5.64 | 5.64 |
479.63 | 3.49 | 3.49 |
417.46 | 3.64 | 3.64 |
501.63 | 5.77 | 5.77 |
413.46 | 2.61 | 2.61 |
420.45 | 2.32 | 2.32 |
283.69 | 3.25 | 3.25 |
287.34 | 2.89 | 2.89 |
421.48 | 4.44 | 4.44 |
343.38 | 2.22 | 2.22 |
327.41 | 3.17 | 3.17 |
266.37 | 3.73 | 3.73 |
348.41 | 1.97 | 1.97 |
404.92 | 6.31 | 6.31 |
309.22 | 5.22 | 5.22 |
411.47 | 4.10 | 4.10 |
471.61 | 5.77 | 5.77 |
398.30 | 5.62 | 5.62 |
349.43 | 2.79 | 2.79 |
431.54 | 4.05 | 4.05 |
355.40 | 4.60 | 4.60 |
368.67 | 6.00 | 6.00 |
309.38 | 3.16 | 3.16 |
245.28 | 1.31 | 1.31 |
159.11 | -2.02 | -2.02 |
324.74 | 5.21 | 5.21 |
490.99 | 3.69 | 3.69 |
382.51 | 4.24 | 4.24 |
280.37 | 3.85 | 3.85 |
334.40 | 1.71 | 1.71 |
472.50 | 4.45 | 4.45 |
338.32 | 3.09 | 3.09 |
414.57 | 3.42 | 3.42 |
326.40 | 1.87 | 1.87 |
568.93 | 6.24 | 6.24 |
328.43 | 2.72 | 2.72 |
437.64 | 4.88 | 4.88 |
341.19 | 2.91 | 2.91 |
358.24 | 4.46 | 4.46 |
381.53 | 4.53 | 4.53 |
373.48 | 4.23 | 4.23 |
379.50 | 3.80 | 3.80 |
231.30 | 2.87 | 2.87 |
538.45 | 2.27 | 2.27 |
367.43 | 1.81 | 1.81 |
421.47 | 2.84 | 2.84 |
446.53 | 2.20 | 2.20 |
391.45 | 1.02 | 1.02 |
433.86 | 3.56 | 3.56 |
422.55 | 5.49 | 5.49 |
297.15 | 1.89 | 1.89 |
343.42 | 3.63 | 3.63 |
305.36 | 1.88 | 1.88 |
366.49 | 4.13 | 4.13 |
568.45 | 4.71 | 4.71 |
302.31 | 2.10 | 2.10 |
302.30 | 2.72 | 2.72 |
305.38 | 4.58 | 4.58 |
311.24 | 4.48 | 4.48 |
330.37 | 2.88 | 2.88 |
356.47 | 2.55 | 2.55 |
407.52 | 2.52 | 2.52 |
366.49 | 4.90 | 4.90 |
332.81 | 4.24 | 4.24 |
396.48 | 5.06 | 5.06 |
389.31 | 5.70 | 5.70 |
512.40 | 5.63 | 5.63 |
325.41 | 3.34 | 3.34 |
316.36 | 3.82 | 3.82 |
368.50 | 4.60 | 4.60 |
326.36 | 4.15 | 4.15 |
384.56 | 3.01 | 3.01 |
426.54 | 2.68 | 2.68 |
302.79 | 4.51 | 4.51 |
320.35 | 1.42 | 1.42 |
307.35 | 0.44 | 0.44 |
379.77 | 5.01 | 5.01 |
564.70 | 4.72 | 4.72 |
492.55 | 4.30 | 4.30 |
411.42 | 4.12 | 4.12 |
338.21 | 4.10 | 4.10 |
325.89 | 4.34 | 4.34 |
440.50 | 5.04 | 5.04 |
370.41 | 2.06 | 2.06 |
321.22 | 0.65 | 0.65 |
405.28 | 4.84 | 4.84 |
524.13 | 5.87 | 5.87 |
272.35 | 3.23 | 3.23 |
244.27 | 0.73 | 0.73 |
425.95 | 4.27 | 4.27 |
435.94 | 4.52 | 4.52 |
313.34 | 3.36 | 3.36 |
377.42 | 4.06 | 4.06 |
380.51 | 5.21 | 5.21 |
299.78 | 4.69 | 4.69 |
365.43 | 4.28 | 4.28 |
353.47 | 3.88 | 3.88 |
360.32 | 2.60 | 2.60 |
346.41 | 2.22 | 2.22 |
256.30 | 2.45 | 2.45 |
437.50 | 4.28 | 4.28 |
430.56 | 3.19 | 3.19 |
280.37 | 3.93 | 3.93 |
279.30 | 2.79 | 2.79 |
228.25 | 2.34 | 2.34 |
392.43 | 1.74 | 1.74 |
365.45 | 3.34 | 3.34 |
338.82 | 2.52 | 2.52 |
417.33 | 5.40 | 5.40 |
371.42 | 3.55 | 3.55 |
268.23 | 1.49 | 1.49 |
415.56 | 3.36 | 3.36 |
319.40 | 4.07 | 4.07 |
372.28 | 2.86 | 2.86 |
346.23 | 3.61 | 3.61 |
472.55 | 2.58 | 2.58 |
349.43 | 3.01 | 3.01 |
384.40 | 2.35 | 2.35 |
445.88 | 4.26 | 4.26 |
301.41 | 3.55 | 3.55 |
475.55 | 2.74 | 2.74 |
435.53 | 3.55 | 3.55 |
420.56 | 4.15 | 4.15 |
404.54 | 4.95 | 4.95 |
371.45 | 3.52 | 3.52 |
293.32 | 2.24 | 2.24 |
393.83 | 4.87 | 4.87 |
314.30 | 2.74 | 2.74 |
243.29 | 2.34 | 2.34 |
463.01 | 5.61 | 5.61 |
472.59 | 3.87 | 3.87 |
433.53 | 5.12 | 5.12 |
247.25 | 1.20 | 1.20 |
445.48 | 3.64 | 3.64 |
404.50 | 4.18 | 4.18 |
367.41 | 4.55 | 4.55 |
264.28 | 2.76 | 2.76 |
367.41 | 2.93 | 2.93 |
366.87 | 4.81 | 4.81 |
328.35 | 2.74 | 2.74 |
421.38 | 4.39 | 4.39 |
348.45 | 3.16 | 3.16 |
429.89 | 2.26 | 2.26 |
343.86 | 2.90 | 2.90 |
359.40 | 3.83 | 3.83 |
406.47 | 4.23 | 4.23 |
349.23 | 5.36 | 5.36 |
289.33 | 3.05 | 3.05 |
463.54 | 2.85 | 2.85 |
428.95 | 4.07 | 4.07 |
362.52 | 4.31 | 4.31 |
335.44 | 4.21 | 4.21 |
434.45 | 4.94 | 4.94 |
363.51 | 4.94 | 4.94 |
398.44 | 4.70 | 4.70 |
493.56 | 5.92 | 5.92 |
212.72 | 2.11 | 2.11 |
379.42 | 3.79 | 3.79 |
325.19 | 3.17 | 3.17 |
450.95 | 5.56 | 5.56 |
351.86 | 4.16 | 4.16 |
378.58 | 3.27 | 3.27 |
411.37 | 4.10 | 4.10 |
352.78 | 3.85 | 3.85 |
376.39 | 1.78 | 1.78 |
491.04 | 6.81 | 6.81 |
402.52 | 5.37 | 5.37 |
378.46 | 3.48 | 3.48 |
360.44 | 1.58 | 1.58 |
381.64 | 4.53 | 4.53 |
443.50 | 2.55 | 2.55 |
294.29 | 2.37 | 2.37 |
436.97 | 5.08 | 5.08 |
343.36 | 4.69 | 4.69 |
386.50 | 3.04 | 3.04 |
269.30 | 2.82 | 2.82 |
360.37 | 3.91 | 3.91 |
370.47 | 3.30 | 3.30 |
257.32 | 3.12 | 3.12 |
238.24 | 2.56 | 2.56 |
448.62 | 5.25 | 5.25 |
264.35 | 1.87 | 1.87 |
425.51 | 3.18 | 3.18 |
443.33 | 4.72 | 4.72 |
289.40 | 2.47 | 2.47 |
328.41 | 3.09 | 3.09 |
458.93 | 3.96 | 3.96 |
331.42 | 3.92 | 3.92 |
348.50 | 2.55 | 2.55 |
238.25 | 1.68 | 1.68 |
269.37 | 2.52 | 2.52 |
454.53 | 4.03 | 4.03 |
309.46 | 4.54 | 4.54 |
133.22 | 0.49 | 0.49 |
402.47 | 2.66 | 2.66 |
323.37 | 4.72 | 4.72 |
486.65 | 4.53 | 4.53 |
422.44 | 5.67 | 5.67 |
322.36 | 2.85 | 2.85 |
257.77 | 3.10 | 3.10 |
492.33 | 4.98 | 4.98 |
296.35 | 3.37 | 3.37 |
387.05 | 4.68 | 4.68 |
262.32 | 3.33 | 3.33 |
322.39 | 2.87 | 2.87 |
364.42 | 2.33 | 2.33 |
187.21 | 0.38 | 0.38 |
293.33 | 2.29 | 2.29 |
378.46 | 4.11 | 4.11 |
334.40 | 2.32 | 2.32 |
308.40 | 2.73 | 2.73 |
313.18 | 3.18 | 3.18 |
348.86 | 3.55 | 3.55 |
310.38 | 3.21 | 3.21 |
235.27 | 1.39 | 1.39 |
322.79 | 4.55 | 4.55 |
352.28 | 4.96 | 4.96 |
378.18 | 3.13 | 3.13 |
323.42 | 4.12 | 4.12 |
348.23 | 4.61 | 4.61 |
296.41 | 4.61 | 4.61 |
394.45 | 2.34 | 2.34 |
324.41 | 3.12 | 3.12 |
291.24 | 1.23 | 1.23 |
319.45 | 4.77 | 4.77 |
328.39 | 3.00 | 3.00 |
510.02 | 3.52 | 3.52 |
320.42 | 2.76 | 2.76 |
447.52 | 1.27 | 1.27 |
480.42 | 3.50 | 3.50 |
362.86 | 3.80 | 3.80 |
357.28 | 6.00 | 6.00 |
409.39 | 3.43 | 3.43 |
362.45 | 3.10 | 3.10 |