Basic Information
ID: ALA1613874
Type: Functional
Description: PUBCHEM_BIOASSAY: Tumor Hsp90 Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 429 (Primary screen preceding this dose response confirmation assay.)]
Format: BAO_0000019
Organism: Homo sapiens
Target: Heat shock protein HSP90(ALA2095165)
Document: ALA1201862
PubChem Source: AID:712
Activity Charts
Bioactivity
Activity Types for Assay ALA1613874
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 322.36 | 2.75 | 2.75 |
| 144.18 | 1.82 | 1.82 |
| 144.18 | 1.82 | 1.82 |
| 276.25 | 2.54 | 2.54 |
| 221.04 | 2.46 | 2.46 |
| 284.31 | 2.55 | 2.55 |
| 175.19 | 1.10 | 1.10 |
| 133.15 | 1.87 | 1.87 |
| 318.37 | 3.58 | 3.58 |
| 322.40 | 3.29 | 3.29 |
| 287.41 | 3.52 | 3.52 |
| 259.35 | 2.69 | 2.69 |
| 287.41 | 3.52 | 3.52 |
| 401.42 | 4.04 | 4.04 |
| 466.83 | 4.29 | 4.29 |
| 356.40 | 3.15 | 3.15 |
| 412.47 | 3.78 | 3.78 |
| 413.46 | 3.06 | 3.06 |
| 342.30 | 4.20 | 4.20 |
| 287.32 | 1.58 | 1.58 |
| 151.13 | -0.82 | -0.82 |
| 276.24 | 1.95 | 1.95 |
| 218.26 | 1.86 | 1.86 |
| 168.20 | 0.64 | 0.64 |
| 399.47 | 2.62 | 2.62 |
| 268.35 | 2.68 | 2.68 |
| 422.49 | 3.86 | 3.86 |
| 300.36 | 2.53 | 2.53 |
| 301.39 | 3.09 | 3.09 |
| 382.40 | 3.32 | 3.32 |
| 335.75 | 2.98 | 2.98 |
| 473.55 | 2.27 | 2.27 |
| 159.19 | 1.40 | 1.40 |
| 280.33 | 1.95 | 1.95 |
| 324.34 | 3.45 | 3.45 |
| 293.34 | 2.50 | 2.50 |
| 243.26 | 2.50 | 2.50 |
| 430.51 | 0.16 | 0.16 |
| 284.31 | 1.57 | 1.57 |
| 397.95 | 3.71 | 3.71 |
| 255.23 | 1.46 | 1.46 |
| 365.43 | 4.46 | 4.46 |
| 345.36 | 1.47 | 1.47 |
| 293.24 | 1.03 | 1.03 |
| 440.84 | 2.66 | 2.66 |
| 274.29 | 3.22 | 3.22 |
| 401.47 | 3.11 | 3.11 |
| 190.16 | 1.85 | 1.85 |
| 443.98 | 3.45 | 3.45 |
| 356.42 | 3.02 | 3.02 |
| 446.33 | 3.66 | 3.66 |
| 442.50 | 1.45 | 1.45 |
| 463.54 | 4.27 | 4.27 |
| 406.44 | 4.41 | 4.41 |
| 318.33 | 2.88 | 2.88 |
| 276.30 | 2.56 | 2.56 |
| 328.27 | 3.90 | 3.90 |
| 277.33 | 2.12 | 2.12 |
| 408.41 | 1.31 | 1.31 |
| 283.34 | 0.22 | 0.22 |
| 283.29 | 0.52 | 0.52 |
| 347.37 | 2.34 | 2.34 |
| 257.32 | 3.33 | 3.33 |
| 343.41 | 2.53 | 2.53 |
| 281.31 | 3.02 | 3.02 |
| 275.26 | 3.12 | 3.12 |
| 308.37 | 3.91 | 3.91 |
| 281.27 | 1.18 | 1.18 |
| 353.41 | 3.09 | 3.09 |
| 333.27 | 1.48 | 1.48 |
| 282.26 | 1.61 | 1.61 |
| 285.32 | 3.59 | 3.59 |
| 388.52 | 3.18 | 3.18 |
| 387.83 | 4.55 | 4.55 |
| 332.40 | 3.51 | 3.51 |
| 404.49 | 2.85 | 2.85 |
| 487.41 | 6.60 | 6.60 |
| 478.57 | 5.31 | 5.31 |
| 260.30 | 1.47 | 1.47 |
| 316.32 | 4.24 | 4.24 |
| 292.40 | 2.49 | 2.49 |
| 366.42 | 4.27 | 4.27 |
| 282.29 | -0.66 | -0.66 |
| 337.35 | 2.23 | 2.23 |
| 335.36 | 2.61 | 2.61 |
| 410.38 | 1.77 | 1.77 |
| 303.37 | 2.14 | 2.14 |
| 273.30 | 2.30 | 2.30 |
| 358.30 | -1.48 | -1.48 |
| 408.76 | 2.88 | 2.88 |
| 372.43 | 4.35 | 4.35 |
| 282.30 | 2.75 | 2.75 |
| 385.40 | 3.35 | 3.35 |
| 294.29 | 2.10 | 2.10 |
| 320.35 | 2.46 | 2.46 |
| 388.38 | 5.44 | 5.44 |
| 381.43 | 4.37 | 4.37 |
| 497.62 | 4.44 | 4.44 |
| 323.35 | 2.64 | 2.64 |
| 332.28 | 2.78 | 2.78 |