Assay Report Card

Basic Information

ID: ALA1613885

Type: Binding

Description: PUBCHEM_BIOASSAY: Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP). Inhibition of the rate of hydrolysis of fluorogenic peptide substrate (H-Leu-NHMec). Secondary screen (Class of assay: confirmatory)

Organism: Plasmodium falciparum 3D7

Strain: 3D7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
406.916.616.61
234.211.211.21
356.065.865.86
286.242.282.28
538.465.135.13
457.394.404.40
223.271.911.91
316.262.292.29
386.312.322.32
320.152.312.31
416.553.733.73
424.095.465.46
512.755.635.63
427.303.303.30
475.532.962.96
294.383.763.76
392.584.484.48
518.474.604.60
215.261.551.55
231.260.850.85
353.603.573.57
594.716.566.56
436.543.433.43
367.453.493.49
543.672.122.12
339.354.194.19
401.472.572.57
425.492.682.68
448.542.432.43
523.644.354.35
466.734.564.56
332.412.972.97
323.823.953.95
452.544.364.36
414.493.943.94
342.394.014.01
382.423.253.25
429.482.672.67
447.933.063.06
356.381.181.18
510.573.743.74
494.603.413.41
418.475.325.32
413.461.751.75
307.783.453.45
309.323.853.85
409.454.834.83
398.883.863.86
346.210.870.87
372.433.093.09
309.793.563.56
392.443.463.46
415.452.372.37
360.442.212.21
460.562.922.92
449.472.562.56
346.733.493.49
455.522.482.48
481.564.804.80
381.441.391.39
479.914.964.96
285.252.452.45
297.362.532.53
499.954.924.92
326.352.902.90
334.352.822.82
505.985.865.86
394.484.584.58
408.502.192.19
392.483.633.63
270.322.652.65
299.364.354.35
368.461.481.48
327.412.832.83
499.955.805.80
403.483.013.01
509.573.593.59
318.372.512.51
396.492.752.75
372.383.173.17
515.574.444.44
399.403.833.83
434.502.272.27
557.265.525.52
350.333.563.56
447.406.426.42
302.371.811.81
383.434.654.65
358.483.023.02
269.302.772.77
527.563.293.29
387.432.482.48
345.814.124.12
487.402.962.96
425.491.381.38
373.823.213.21
340.405.435.43
407.472.792.79
531.413.983.98
415.913.963.96
425.444.544.54
388.884.004.00
431.544.454.45
379.380.520.52
690.861.581.58
400.873.933.93
325.371.381.38
208.313.683.68
364.473.013.01
419.484.554.55
457.554.324.32
344.372.992.99
427.512.662.66
308.102.562.56
338.412.852.85
293.19-0.57-0.57
434.524.134.13
563.731.961.96
377.831.831.83
387.864.994.99
347.403.513.51
450.303.753.75
382.431.951.95
468.906.776.77
367.362.062.06
410.813.663.66
515.621.481.48
380.453.593.59
433.494.134.13
330.364.984.98
470.503.973.97
496.392.872.87
418.843.203.20
334.403.173.17
397.272.952.95
260.251.231.23
360.482.542.54
387.402.642.64
357.844.114.11
343.474.394.39
407.492.952.95
392.515.665.66
473.603.263.26
345.814.444.44
454.283.473.47
432.324.524.52
345.882.602.60
397.502.572.57
404.492.352.35
449.472.562.56
359.382.052.05
370.824.874.87
453.603.093.09
317.433.923.92
466.543.903.90
325.402.782.78
491.603.573.57
463.544.464.46
395.514.664.66
368.466.076.07
245.291.241.24
473.562.352.35
479.572.482.48
486.985.215.21
433.452.032.03
354.223.873.87
468.565.645.64
538.035.395.39
441.492.872.87
399.863.613.61
336.822.602.60
337.854.344.34
457.275.045.04
433.902.752.75
331.422.952.95
348.412.542.54
459.465.675.67
415.414.514.51
398.943.123.12
421.504.014.01
450.523.183.18
318.383.433.43
336.404.054.05
553.534.424.42
322.792.212.21
369.361.561.56
382.482.602.60
396.442.992.99
362.433.373.37
296.373.083.08
399.452.102.10
333.353.193.19
537.073.233.23
215.261.101.10
422.512.502.50
358.442.942.94
458.544.654.65
436.542.802.80
469.524.094.09
354.393.033.03
408.512.732.73
474.544.654.65
397.454.414.41
339.353.413.41
350.852.852.85
214.223.513.51
411.503.853.85
424.574.244.24
403.415.185.18
301.393.363.36
487.265.605.60
291.313.813.81
380.360.790.79
394.285.725.72
408.461.801.80
377.812.862.86
492.504.234.23
386.524.684.68
537.405.215.21
424.532.772.77
390.421.531.53
480.593.123.12
401.472.732.73
395.422.682.68
505.603.843.84
342.263.493.49
282.433.033.03
359.902.912.91
313.403.363.36
479.633.493.49
478.675.065.06
269.261.681.68
429.533.183.18
458.285.055.05
312.332.072.07
392.482.932.93
377.433.523.52
308.314.714.71
319.35-0.54-0.54
288.692.332.33
347.372.632.63
391.391.081.08
387.422.242.24
271.322.312.31
435.873.653.65
401.472.682.68
404.173.533.53
457.511.641.64
476.654.674.67
429.572.742.74
400.442.572.57
456.355.665.66
239.282.782.78
440.512.842.84
521.531.721.72
476.335.665.66
368.394.164.16
276.291.951.95
275.352.902.90
436.703.803.80
337.27-0.38-0.38
428.444.034.03
217.221.911.91
363.461.621.62
281.363.833.83
385.473.723.72
492.552.782.78
482.533.883.88
328.352.842.84
446.482.232.23
378.414.124.12
415.493.733.73
466.563.933.93
455.934.074.07
447.523.443.44
348.354.534.53
482.274.114.11
442.455.365.36
425.484.394.39
392.644.654.65
415.493.823.82
272.332.662.66
449.423.293.29
335.843.323.32
395.463.833.83
361.493.343.34
361.362.712.71
401.493.633.63
375.472.402.40
399.294.204.20
293.351.041.04
280.551.921.92
370.320.380.38
305.341.991.99
360.464.534.53
408.424.654.65
393.493.973.97
387.463.243.24
440.212.672.67
476.563.223.22
473.451.901.90
466.474.484.48
403.442.682.68
437.573.193.19
418.522.422.42
385.402.872.87
517.974.254.25
545.394.424.42
370.522.532.53
456.344.034.03
316.402.672.67
234.282.402.40
380.384.064.06
413.454.094.09
301.802.192.19
369.431.221.22
421.432.012.01
233.303.103.10
408.372.982.98
299.372.892.89
498.664.894.89
403.233.803.80
520.016.256.25
383.494.234.23
407.472.792.79
453.455.795.79
339.273.593.59
340.411.411.41
357.483.273.27
353.363.983.98
289.332.492.49
316.814.024.02
270.313.243.24
473.563.523.52
401.473.433.43
354.844.094.09
396.452.742.74
392.48
396.431.271.27
214.222.502.50
361.443.103.10
359.463.823.82
421.523.263.26
461.453.923.92
292.752.962.96
491.744.124.12
445.254.434.43
359.422.752.75
397.502.912.91
335.413.563.56
456.972.372.37
335.792.472.47
361.433.823.82
395.463.413.41
361.473.783.78
431.501.761.76
391.464.704.70
346.452.232.23
521.603.543.54
432.442.432.43
569.604.834.83
411.502.212.21
225.252.662.66
404.563.703.70
315.372.212.21
409.512.952.95
224.272.392.39
502.603.683.68
437.914.184.18
438.515.185.18
454.532.862.86
484.643.653.65
415.493.303.30
430.584.044.04
450.834.804.80
336.822.462.46
345.472.452.45
335.434.494.49
292.293.193.19
417.495.465.46
499.592.502.50
551.593.903.90
362.442.772.77
516.533.653.65
340.385.115.11
434.456.116.11
500.522.732.73
517.553.833.83
371.373.293.29
321.803.693.69
368.431.551.55
474.613.403.40
457.601.081.08
369.852.362.36
485.513.713.71
241.323.133.13
405.465.445.44
383.453.843.84
273.26-0.34-0.34
464.573.563.56
440.212.672.67
477.593.043.04
365.802.802.80
543.672.122.12
429.533.123.12
498.544.494.49
322.390.910.91
345.321.951.95
408.411.571.57
464.593.503.50
365.441.241.24
369.442.342.34
441.513.163.16
414.264.704.70
487.582.362.36
356.402.922.92
466.833.553.55
446.333.473.47
614.65
338.301.801.80
394.391.181.18
468.441.341.34
430.563.103.10
234.282.872.87
576.61-0.02-0.02
489.925.405.40
364.522.752.75
566.715.595.59
427.512.722.72
507.633.033.03
472.935.135.13
405.465.445.44
327.382.382.38
390.482.682.68
420.454.714.71
314.352.542.54
443.443.293.29
495.564.794.79
411.484.274.27
428.503.353.35
485.575.525.52
479.492.572.57
273.363.693.69
412.564.304.30
233.292.462.46
381.442.562.56
458.594.594.59
243.692.312.31
384.394.434.43
418.452.372.37
385.431.961.96
351.412.312.31
475.454.124.12
464.525.155.15
514.565.985.98
529.985.815.81
395.463.833.83
426.462.972.97
392.443.383.38
325.393.113.11
401.352.932.93
366.344.674.67
372.220.890.89
261.322.432.43
382.512.842.84
335.834.004.00
331.713.613.61
543.672.262.26
313.744.504.50
435.874.654.65
345.453.243.24
324.432.412.41
394.414.264.26
399.422.392.39
529.641.871.87
458.545.965.96
327.364.274.27
437.972.922.92
339.332.282.28
404.543.213.21
449.993.983.98
364.402.242.24
333.303.673.67
416.483.603.60
326.262.592.59
422.531.621.62
295.773.303.30
421.554.204.20
342.360.790.79
513.963.773.77
366.432.542.54
412.830.170.17
309.414.484.48
378.504.094.09
306.711.831.83
411.461.071.07
432.474.404.40
338.411.261.26
286.383.853.85
442.613.783.78
425.422.782.78
405.823.943.94
464.552.912.91
443.543.033.03
307.783.093.09
361.913.463.46
478.675.065.06
396.543.153.15
342.441.891.89
419.534.744.74
475.484.724.72
421.164.264.26
453.543.503.50
440.553.643.64
406.804.204.20
383.812.702.70
434.434.434.43
344.761.471.47
313.403.283.28
219.272.342.34
414.493.853.85
489.584.894.89
351.753.993.99
324.433.863.86
429.434.904.90
424.803.683.68
500.142.102.10
381.484.474.47
495.564.794.79
219.272.792.79
237.612.162.16
409.384.134.13
373.923.623.62
425.775.635.63
497.604.074.07
483.544.404.40
323.333.973.97
282.261.321.32
359.432.282.28
373.413.433.43
403.461.531.53
401.412.862.86
408.372.982.98
380.472.712.71
346.341.561.56
349.812.862.86
380.453.593.59
367.473.193.19
463.332.592.59
333.353.193.19
361.513.463.46
357.353.753.75
455.564.514.51
387.493.883.88
552.054.714.71
522.535.235.23
397.442.262.26
435.873.503.50
252.282.582.58
384.322.862.86
411.504.284.28
454.534.034.03
378.824.134.13
384.413.423.42
436.703.803.80
356.291.361.36
499.544.104.10
315.413.613.61
416.512.662.66
364.402.242.24
287.362.832.83
323.823.863.86
518.624.714.71
415.493.733.73
513.544.164.16
454.243.643.64
275.692.202.20
442.231.991.99
458.865.965.96
522.365.085.08
459.624.504.50
490.521.811.81
333.260.780.78
427.371.731.73
419.282.072.07
372.383.353.35
279.303.573.57
351.324.004.00
493.505.195.19
331.754.304.30
318.333.013.01
471.432.782.78
373.173.533.53
449.533.873.87
527.605.495.49
361.242.362.36
419.511.671.67
351.324.004.00
397.443.813.81
504.913.963.96
491.552.562.56
340.773.143.14
452.264.454.45
353.603.573.57
429.433.323.32
536.164.384.38
308.794.444.44
294.313.603.60
483.895.445.44
237.652.222.22
362.570.880.88
375.732.032.03
457.493.943.94
422.812.902.90
410.433.793.79
322.322.192.19
235.271.391.39
335.342.522.52
376.212.032.03
505.564.094.09
337.332.612.61
258.071.161.16
471.432.782.78
471.302.002.00
305.342.182.18
486.605.925.92
324.680.700.70
476.635.905.90
343.301.591.59
418.453.183.18
293.333.133.13
505.564.094.09
341.373.633.63
484.385.055.05
283.723.513.51
261.312.682.68
455.112.802.80
462.922.212.21
354.232.992.99
482.882.942.94
531.533.783.78
301.141.381.38
497.513.233.23
377.201.431.43
396.202.032.03
416.282.622.62
386.754.054.05
329.751.291.29
399.864.624.62
402.253.053.05
374.741.851.85
437.833.793.79
391.231.731.73
437.884.374.37
400.794.134.13
323.701.751.75
497.513.233.23
468.545.075.07
436.853.693.69
401.201.191.19
404.424.204.20
341.313.063.06
222.641.301.30
400.493.023.02
364.202.112.11
509.034.194.19
447.903.323.32
488.623.843.84
357.321.901.90
414.513.323.32
335.350.530.53