Basic Information
ID: ALA1613893
Type: Functional
Description: PUBCHEM_BIOASSAY: TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3). (Class of assay: confirmatory) [Related pubchem assays: 2379 (Screening (NR2E3 agonists, 3X)), 2325 (Summary), 2300 (Screening (NR2E3 agonists, 1X))]
Format: BAO_0000019
Organism: Homo sapiens
Target: Photoreceptor-specific nuclear receptor(ALA4374)
Document: ALA1201862
PubChem Source: AID:2758
Activity Charts
Bioactivity
Activity Types for Assay ALA1613893
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 208.22 | 2.73 | 2.73 |
| 334.19 | 4.42 | 4.42 |
| 207.19 | -1.32 | -1.32 |
| 193.17 | -1.63 | -1.63 |
| 289.31 | 2.90 | 2.90 |
| 214.26 | 1.09 | 1.09 |
| 284.28 | 1.56 | 1.56 |
| 403.39 | 5.13 | 5.13 |
| 284.41 | 4.21 | 4.21 |
| 580.66 | 4.01 | 4.01 |
| 372.76 | 2.78 | 2.78 |
| 510.62 | 4.76 | 4.76 |
| 258.35 | 2.97 | 2.97 |
| 454.32 | 4.73 | 4.73 |
| 328.38 | 3.95 | 3.95 |
| 373.41 | 4.59 | 4.59 |
| 493.31 | 4.35 | 4.35 |
| 272.37 | 3.43 | 3.43 |
| 422.34 | -0.72 | -0.72 |
| 332.15 | 4.26 | 4.26 |
| 246.65 | 3.31 | 3.31 |
| 312.33 | 3.93 | 3.93 |
| 434.84 | 5.17 | 5.17 |
| 272.37 | 3.36 | 3.36 |
| 301.44 | 5.09 | 5.09 |
| 490.47 | 4.54 | 4.54 |
| 326.40 | 4.41 | 4.41 |
| 430.42 | 4.52 | 4.52 |
| 582.61 | 3.46 | 3.46 |
| 317.43 | 3.26 | 3.26 |
| 295.13 | 3.73 | 3.73 |
| 367.24 | 3.76 | 3.76 |
| 287.39 | 3.74 | 3.74 |
| 460.44 | 4.53 | 4.53 |
| 450.47 | 3.48 | 3.48 |
| 406.75 | 4.57 | 4.57 |
| 330.37 | 4.39 | 4.39 |
| 400.39 | 4.20 | 4.20 |
| 243.70 | 3.16 | 3.16 |
| 419.32 | 4.49 | 4.49 |
| 435.48 | 3.85 | 3.85 |
| 458.43 | 4.30 | 4.30 |
| 433.51 | 4.14 | 4.14 |
| 432.41 | 3.73 | 3.73 |
| 372.35 | 4.46 | 4.46 |
| 458.28 | 5.05 | 5.05 |
| 453.29 | 4.52 | 4.52 |
| 424.46 | 4.65 | 4.65 |
| 458.47 | 5.30 | 5.30 |
| 466.49 | 2.33 | 2.33 |
| 474.20 | 3.60 | 3.60 |
| 438.51 | 3.40 | 3.40 |
| 274.34 | 0.21 | 0.21 |
| 243.26 | 1.13 | 1.13 |
| 470.91 | 2.98 | 2.98 |
| 480.95 | 4.39 | 4.39 |
| 268.11 | 3.19 | 3.19 |
| 270.25 | -0.56 | -0.56 |
| 315.15 | 3.36 | 3.36 |
| 466.92 | 4.00 | 4.00 |
| 201.22 | 2.37 | 2.37 |
| 246.38 | 3.32 | 3.32 |
| 391.43 | 3.99 | 3.99 |
| 324.36 | 3.80 | 3.80 |
| 372.17 | 4.09 | 4.09 |
| 406.42 | 4.57 | 4.57 |
| 334.21 | 4.27 | 4.27 |
| 308.36 | 4.10 | 4.10 |
| 404.47 | 3.96 | 3.96 |
| 452.24 | 3.94 | 3.94 |
| 353.38 | 1.96 | 1.96 |
| 393.44 | 2.53 | 2.53 |
| 315.15 | 1.84 | 1.84 |
| 243.29 | 2.44 | 2.44 |
| 371.42 | 3.55 | 3.55 |
| 479.29 | 5.27 | 5.27 |
| 322.39 | 4.41 | 4.41 |
| 338.77 | 3.02 | 3.02 |
| 456.45 | 5.08 | 5.08 |
| 395.44 | 3.53 | 3.53 |
| 371.08 | 4.15 | 4.15 |
| 407.85 | 5.25 | 5.25 |
| 270.36 | 3.69 | 3.69 |
| 272.37 | 2.94 | 2.94 |
| 469.34 | 4.34 | 4.34 |
| 312.38 | 4.25 | 4.25 |
| 356.22 | 3.96 | 3.96 |
| 353.41 | 2.54 | 2.54 |
| 511.37 | 4.11 | 4.11 |
| 331.47 | 4.24 | 4.24 |
| 430.42 | 4.52 | 4.52 |
| 466.49 | 5.55 | 5.55 |
| 432.27 | 4.26 | 4.26 |
| 414.42 | 4.82 | 4.82 |
| 296.35 | 3.22 | 3.22 |
| 443.29 | 5.07 | 5.07 |
| 422.26 | 4.34 | 4.34 |
| 468.53 | 3.41 | 3.41 |
| 308.36 | 4.10 | 4.10 |
| 427.48 | 2.89 | 2.89 |