ID: ALA1613917
Type: Binding
Description: PUBCHEM_BIOASSAY: uHTS identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a fluorescence resonance energy transfer (FRET) assay. Inhibition of protein-protein interaction using fluorescence resonance energy transfer (FRET) assay Secondary Screen (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1438, AID1496, AID1502, AID1550, AID1560, AID1645]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1613917
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
293.33 | 3.30 | 3.30 |
301.31 | 2.87 | 2.87 |
285.39 | 4.93 | 4.93 |
321.80 | 2.85 | 2.85 |
579.67 | 5.05 | 5.05 |
443.44 | 2.84 | 2.84 |
253.30 | 2.72 | 2.72 |
254.33 | 2.99 | 2.99 |
413.48 | 4.04 | 4.04 |
407.93 | 4.87 | 4.87 |
194.22 | 1.62 | 1.62 |
548.40 | 4.62 | 4.62 |
274.67 | 1.33 | 1.33 |
396.36 | 2.63 | 2.63 |
282.39 | 2.24 | 2.24 |
494.57 | 6.24 | 6.24 |
389.45 | 2.63 | 2.63 |
421.46 | 4.54 | 4.54 |
415.91 | 3.96 | 3.96 |
446.49 | 2.91 | 2.91 |
380.30 | 4.43 | 4.43 |
460.49 | 1.52 | 1.52 |
341.40 | 1.93 | 1.93 |
252.32 | 2.77 | 2.77 |
254.31 | 3.01 | 3.01 |
439.48 | 3.01 | 3.01 |
257.29 | 2.25 | 2.25 |
354.79 | 3.82 | 3.82 |
373.51 | 3.81 | 3.81 |
438.56 | 5.08 | 5.08 |
431.50 | 3.06 | 3.06 |
428.44 | 4.51 | 4.51 |
303.79 | 2.85 | 2.85 |
336.40 | 4.05 | 4.05 |
397.41 | 3.04 | 3.04 |
320.40 | 2.61 | 2.61 |
310.25 | 3.35 | 3.35 |
462.51 | 4.44 | 4.44 |
403.49 | 4.55 | 4.55 |
330.34 | 3.27 | 3.27 |
472.51 | 1.45 | 1.45 |
470.55 | 4.81 | 4.81 |
420.47 | 1.87 | 1.87 |
444.53 | 5.17 | 5.17 |
412.54 | 3.49 | 3.49 |
373.41 | 3.21 | 3.21 |
429.46 | 4.07 | 4.07 |
433.53 | 4.45 | 4.45 |
416.48 | 4.53 | 4.53 |
194.22 | 1.62 | 1.62 |
401.51 | 3.42 | 3.42 |
432.46 | 2.60 | 2.60 |
486.41 | 5.46 | 5.46 |
371.47 | 1.50 | 1.50 |
264.28 | 2.66 | 2.66 |
323.39 | 3.92 | 3.92 |
474.49 | 4.20 | 4.20 |
363.42 | 3.19 | 3.19 |
339.78 | 3.68 | 3.68 |
245.28 | 2.23 | 2.23 |
425.45 | 2.70 | 2.70 |
363.48 | 2.58 | 2.58 |
304.40 | 3.90 | 3.90 |
483.53 | 4.24 | 4.24 |
418.48 | 3.95 | 3.95 |
570.06 | 5.30 | 5.30 |
224.26 | 3.52 | 3.52 |
491.55 | 3.11 | 3.11 |
385.54 | 5.33 | 5.33 |
339.40 | 3.85 | 3.85 |
240.26 | 2.68 | 2.68 |
415.45 | 3.84 | 3.84 |
418.48 | 3.95 | 3.95 |
409.44 | 2.61 | 2.61 |
492.56 | 2.62 | 2.62 |
328.38 | 4.05 | 4.05 |
372.43 | 5.15 | 5.15 |
423.43 | 4.19 | 4.19 |
404.90 | 4.21 | 4.21 |
340.34 | 2.99 | 2.99 |
411.38 | 2.50 | 2.50 |
449.47 | 3.52 | 3.52 |
439.54 | 6.52 | 6.52 |
482.50 | 3.52 | 3.52 |
462.55 | 5.02 | 5.02 |
465.47 | 3.22 | 3.22 |
482.97 | 5.37 | 5.37 |
278.31 | 2.99 | 2.99 |