ID: ALA1613928
Type: Functional
Description: PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 594 (Rhodamine region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2549 (qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))]
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA1613928
Potency
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
302.19 | 1.31 | 1.31 |
211.22 | 0.44 | 0.44 |
302.37 | 3.57 | 3.57 |
444.49 | -0.14 | -0.14 |
153.18 | 0.60 | 0.60 |
422.35 | 2.45 | 2.45 |
242.27 | 2.75 | 2.75 |
305.76 | 2.73 | 2.73 |
246.31 | 4.49 | 4.49 |
327.39 | 5.09 | 5.09 |
183.21 | 0.35 | 0.35 |
1297.30 | ||
504.45 | 5.08 | 5.08 |
183.21 | 0.48 | 0.48 |
286.24 | 2.28 | 2.28 |
284.22 | 1.57 | 1.57 |
174.16 | 1.33 | 1.33 |
518.56 | 6.38 | 6.38 |
448.44 | 1.65 | 1.65 |
282.30 | 2.23 | 2.23 |
348.49 | 6.10 | 6.10 |
353.47 | 1.94 | 1.94 |
497.50 | 1.02 | 1.02 |
314.25 | 2.82 | 2.82 |
368.48 | 4.88 | 4.88 |
213.19 | -0.24 | -0.24 |
456.68 | 6.17 | 6.17 |
169.18 | 0.30 | 0.30 |
415.50 | -0.32 | -0.32 |
332.31 | 3.97 | 3.97 |
302.24 | 1.39 | 1.39 |
318.24 | 1.10 | 1.10 |
290.27 | 1.55 | 1.55 |
197.19 | 0.05 | 0.05 |
225.21 | -1.33 | -1.33 |
169.18 | 0.09 | 0.09 |
328.35 | 2.72 | 2.72 |
210.30 | 2.98 | 2.98 |
243.31 | 2.97 | 2.97 |
229.28 | 2.85 | 2.85 |
1255.44 | ||
205.64 | 0.30 | 0.30 |
223.23 | 0.54 | 0.54 |
440.41 | 5.18 | 5.18 |
285.39 | 4.93 | 4.93 |
579.99 | 0.00 | 0.00 |
327.43 | 5.95 | 5.95 |
160.18 | 1.11 | 1.11 |
376.37 | -1.72 | -1.72 |
513.50 | 0.73 | 0.73 |
241.25 | 2.05 | 2.05 |
372.86 | 3.67 | 3.67 |
402.41 | 4.79 | 4.79 |
472.89 | 5.97 | 5.97 |
289.32 | 0.59 | 0.59 |
392.50 | 2.39 | 2.39 |
340.39 | 3.94 | 3.94 |
385.38 | 3.96 | 3.96 |
305.76 | 2.73 | 2.73 |
310.39 | 4.45 | 4.45 |
973.67 | 9.00 | 9.00 |
454.55 | 2.40 | 2.40 |
432.48 | 2.04 | 2.04 |
398.44 | 2.92 | 2.92 |
443.58 | 4.19 | 4.19 |
335.43 | 4.57 | 4.57 |
436.49 | 4.28 | 4.28 |
251.33 | 3.06 | 3.06 |
449.52 | 2.30 | 2.30 |
444.47 | 3.08 | 3.08 |
325.32 | 2.12 | 2.12 |
391.42 | 4.45 | 4.45 |
422.35 | 0.88 | 0.88 |
437.50 | 3.21 | 3.21 |
862.75 | -1.10 | -1.10 |
372.43 | 3.09 | 3.09 |
1056.40 | 2.75 | 2.75 |
378.37 | 2.99 | 2.99 |
279.32 | 2.12 | 2.12 |
282.25 | 2.75 | 2.75 |
224.24 | 0.41 | 0.41 |
300.34 | 3.37 | 3.37 |
490.54 | 5.25 | 5.25 |
267.24 | 3.33 | 3.33 |
444.54 | 2.47 | 2.47 |
528.66 | 5.74 | 5.74 |
365.46 | 2.25 | 2.25 |
396.47 | 4.20 | 4.20 |
397.39 | 4.08 | 4.08 |
419.44 | 3.13 | 3.13 |
300.31 | 3.43 | 3.43 |
444.45 | 3.02 | 3.02 |
398.38 | 3.89 | 3.89 |
359.38 | 3.99 | 3.99 |
539.71 | 4.12 | 4.12 |
304.40 | 3.25 | 3.25 |
369.45 | 3.66 | 3.66 |
451.12 | 3.70 | 3.70 |
380.51 | 4.45 | 4.45 |
470.24 | 3.78 | 3.78 |
430.55 | 3.52 | 3.52 |
339.15 | 1.91 | 1.91 |
224.33 | 3.87 | 3.87 |
294.35 | 4.82 | 4.82 |
275.37 | 3.73 | 3.73 |
270.25 | 2.74 | 2.74 |
341.39 | 2.62 | 2.62 |
311.30 | 1.59 | 1.59 |
482.52 | 3.65 | 3.65 |
606.07 | 2.16 | 2.16 |
436.99 | 6.51 | 6.51 |
409.51 | 4.08 | 4.08 |
360.76 | 3.57 | 3.57 |
460.52 | 4.22 | 4.22 |
385.46 | 5.74 | 5.74 |
142.54 | 0.82 | 0.82 |
378.39 | 3.65 | 3.65 |
458.45 | 3.57 | 3.57 |
431.45 | 4.13 | 4.13 |
425.47 | 4.06 | 4.06 |
394.46 | 3.24 | 3.24 |
402.36 | 1.87 | 1.87 |
458.92 | 5.05 | 5.05 |
184.15 | -0.59 | -0.59 |
340.43 | 3.99 | 3.99 |
956.68 | 0.02 | 0.02 |
315.37 | 5.11 | 5.11 |
318.13 | 3.96 | 3.96 |
499.55 | 5.28 | 5.28 |
496.47 | -1.24 | -1.24 |
327.45 | 4.87 | 4.87 |
357.42 | 2.78 | 2.78 |
436.42 | 1.96 | 1.96 |
581.67 | 1.99 | 1.99 |
305.32 | -0.93 | -0.93 |
383.45 | 3.28 | 3.28 |
323.42 | 3.65 | 3.65 |
404.49 | 4.67 | 4.67 |
371.36 | 5.21 | 5.21 |
424.53 | 2.77 | 2.77 |
497.57 | 2.86 | 2.86 |
353.42 | 4.02 | 4.02 |
517.41 | -0.14 | -0.14 |
287.36 | 2.97 | 2.97 |
404.90 | 4.69 | 4.69 |
556.49 | 4.53 | 4.53 |
326.38 | 3.41 | 3.41 |
449.63 | 3.72 | 3.72 |
366.37 | 3.42 | 3.42 |
407.81 | 3.93 | 3.93 |
336.35 | 3.06 | 3.06 |
464.57 | 3.53 | 3.53 |
283.28 | 2.55 | 2.55 |
278.31 | 3.39 | 3.39 |
252.36 | 2.13 | 2.13 |
444.45 | 3.02 | 3.02 |
225.29 | 2.71 | 2.71 |
416.48 | 3.60 | 3.60 |
445.38 | 4.73 | 4.73 |
314.34 | 4.39 | 4.39 |
447.52 | 3.44 | 3.44 |
398.50 | 6.38 | 6.38 |
490.99 | 4.06 | 4.06 |
353.40 | 4.67 | 4.67 |
453.41 | 2.51 | 2.51 |
432.55 | 2.59 | 2.59 |
310.38 | 4.23 | 4.23 |
442.42 | 0.56 | 0.56 |
462.51 | 2.47 | 2.47 |
336.13 | 1.42 | 1.42 |
335.39 | 4.68 | 4.68 |
868.71 | 4.18 | 4.18 |
387.44 | 2.34 | 2.34 |
211.22 | 0.44 | 0.44 |
396.86 | 5.64 | 5.64 |
471.58 | 2.65 | 2.65 |
323.35 | 3.52 | 3.52 |
237.31 | 3.43 | 3.43 |
390.26 | 4.23 | 4.23 |
324.41 | 3.88 | 3.88 |
317.73 | 3.06 | 3.06 |
315.42 | 3.99 | 3.99 |
420.47 | 2.62 | 2.62 |
426.37 | 4.17 | 4.17 |
374.49 | 3.13 | 3.13 |
336.35 | 2.04 | 2.04 |
384.46 | 4.35 | 4.35 |
311.36 | 0.84 | 0.84 |
315.41 | 3.75 | 3.75 |
366.51 | 4.71 | 4.71 |
358.40 | 4.86 | 4.86 |
432.51 | 4.01 | 4.01 |
423.50 | 2.27 | 2.27 |
199.30 | 1.96 | 1.96 |
332.36 | 1.95 | 1.95 |
301.39 | 3.36 | 3.36 |
477.50 | 4.43 | 4.43 |
478.89 | -0.44 | -0.44 |
409.47 | 3.33 | 3.33 |
432.35 | 5.04 | 5.04 |
330.48 | 2.22 | 2.22 |
329.40 | 3.95 | 3.95 |
357.44 | 2.85 | 2.85 |
475.29 | 4.42 | 4.42 |
303.11 | 3.50 | 3.50 |
352.41 | 4.51 | 4.51 |
256.30 | 3.03 | 3.03 |
940.68 | 1.69 | 1.69 |
461.57 | 3.84 | 3.84 |
386.52 | 4.99 | 4.99 |
353.41 | 3.09 | 3.09 |
399.49 | 6.05 | 6.05 |
358.85 | 4.53 | 4.53 |
408.46 | 3.75 | 3.75 |
381.50 | 2.88 | 2.88 |
543.53 | 0.00 | 0.00 |
428.39 | 1.41 | 1.41 |
442.38 | 2.53 | 2.53 |
296.37 | 3.44 | 3.44 |
312.44 | 3.20 | 3.20 |
338.27 | 1.99 | 1.99 |
254.31 | 3.52 | 3.52 |
353.47 | 3.97 | 3.97 |
445.48 | 3.05 | 3.05 |
337.89 | ||
458.59 | 4.59 | 4.59 |
478.51 | 3.34 | 3.34 |
262.27 | 3.59 | 3.59 |
231.25 | 1.93 | 1.93 |
396.36 | 1.93 | 1.93 |
358.28 | 5.19 | 5.19 |
338.46 | 2.84 | 2.84 |
174.63 | 0.97 | 0.97 |
538.67 | 2.20 | 2.20 |
352.39 | 3.52 | 3.52 |
438.51 | 3.35 | 3.35 |
439.49 | 4.45 | 4.45 |
804.70 | ||
378.45 | 1.38 | 1.38 |
408.44 | 3.62 | 3.62 |
410.43 | 3.81 | 3.81 |
327.34 | 2.97 | 2.97 |
403.89 | 4.12 | 4.12 |
365.41 | 3.03 | 3.03 |
314.18 | 2.66 | 2.66 |
267.29 | 2.65 | 2.65 |
404.47 | 4.20 | 4.20 |
411.93 | 4.20 | 4.20 |
455.94 | 5.70 | 5.70 |
416.48 | 3.60 | 3.60 |
359.43 | 3.05 | 3.05 |
586.20 | 8.95 | 8.95 |
504.01 | 4.83 | 4.83 |
349.44 | 3.39 | 3.39 |
284.27 | 1.62 | 1.62 |
372.45 | 4.09 | 4.09 |
421.45 | 3.25 | 3.25 |
442.42 | -0.44 | -0.44 |
329.31 | 3.22 | 3.22 |
348.22 | 4.75 | 4.75 |
682.15 | ||
305.72 | 1.24 | 1.24 |
592.64 | 3.00 | 3.00 |
504.64 | 4.52 | 4.52 |
233.30 | 1.68 | 1.68 |
434.43 | 4.43 | 4.43 |
769.90 | 5.31 | 5.31 |
468.73 | 4.64 | 4.64 |
316.74 | 3.83 | 3.83 |
490.47 | 3.12 | 3.12 |
439.92 | 5.22 | 5.22 |
310.35 | 4.58 | 4.58 |
287.34 | 2.69 | 2.69 |
396.24 | 5.19 | 5.19 |
465.55 | 4.51 | 4.51 |
280.30 | 2.26 | 2.26 |
426.33 | 4.34 | 4.34 |
405.52 | 4.34 | 4.34 |
419.44 | 2.39 | 2.39 |
229.28 | 3.45 | 3.45 |
343.80 | 3.86 | 3.86 |
346.35 | 2.85 | 2.85 |
279.39 | 3.95 | 3.95 |
148.17 | 0.73 | 0.73 |
497.58 | 5.89 | 5.89 |
277.37 | 3.73 | 3.73 |
695.05 | ||
427.57 | 1.41 | 1.41 |
387.40 | 3.26 | 3.26 |
750.66 | ||
221.26 | 4.00 | 4.00 |
622.54 | 1.91 | 1.91 |
394.38 | 3.23 | 3.23 |
483.40 | 5.49 | 5.49 |
288.35 | 3.08 | 3.08 |
478.46 | 6.02 | 6.02 |
499.60 | 4.02 | 4.02 |
421.55 | 4.82 | 4.82 |
447.44 | 3.27 | 3.27 |
513.54 | 4.16 | 4.16 |
506.97 | 5.43 | 5.43 |
359.36 | 4.40 | 4.40 |
359.36 | 4.40 | 4.40 |
300.27 | 1.08 | 1.08 |
371.40 | 3.86 | 3.86 |
305.83 | 3.69 | 3.69 |
284.31 | 2.78 | 2.78 |
404.25 | 2.73 | 2.73 |
464.43 | 1.80 | 1.80 |
355.35 | 1.38 | 1.38 |
427.37 | 1.73 | 1.73 |
284.32 | 1.00 | 1.00 |
362.39 | 4.66 | 4.66 |
361.24 | 2.36 | 2.36 |
481.92 | 3.93 | 3.93 |
478.89 | -0.44 | -0.44 |
322.32 | 3.15 | 3.15 |
924.09 | 0.71 | 0.71 |
298.25 | 1.43 | 1.43 |
421.48 | 2.66 | 2.66 |
379.38 | 3.54 | 3.54 |
337.36 | 1.24 | 1.24 |
419.47 | 2.80 | 2.80 |
397.53 | 4.02 | 4.02 |
278.29 | 2.51 | 2.51 |
393.83 | 4.06 | 4.06 |
568.70 | 3.02 | 3.02 |
320.76 | 3.21 | 3.21 |
233.31 | 2.86 | 2.86 |
340.41 | 3.07 | 3.07 |
460.49 | 2.71 | 2.71 |