Basic Information
ID: ALA1613948
Type: Functional
Description: PUBCHEM_BIOASSAY: Cell-based secondary assay for identifying Hsp90 inhibitors that degrade Hsp90 client protein Her2. (Class of assay: confirmatory) [Related pubchem assays: 429 (Primary screen preceding this dose response confirmation assay.)]
Format: BAO_0000019
Organism: Homo sapiens
Target: Heat shock protein HSP90(ALA2095165)
Document: ALA1201862
PubChem Source: AID:754
Activity Charts
Bioactivity
Activity Types for Assay ALA1613948
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.37 | 3.57 | 3.57 |
| 259.35 | 2.78 | 2.78 |
| 329.49 | 4.27 | 4.27 |
| 283.74 | 2.85 | 2.85 |
| 284.31 | 2.55 | 2.55 |
| 175.19 | 1.10 | 1.10 |
| 563.99 | 1.03 | 1.03 |
| 320.38 | 3.50 | 3.50 |
| 322.40 | 3.29 | 3.29 |
| 579.99 | 0.00 | 0.00 |
| 287.41 | 3.52 | 3.52 |
| 273.38 | 3.04 | 3.04 |
| 315.46 | 4.17 | 4.17 |
| 301.43 | 3.82 | 3.82 |
| 245.33 | 2.39 | 2.39 |
| 301.43 | 3.82 | 3.82 |
| 423.56 | 5.62 | 5.62 |
| 378.52 | 5.13 | 5.13 |
| 317.43 | 3.40 | 3.40 |
| 245.33 | 2.48 | 2.48 |
| 259.35 | 2.69 | 2.69 |
| 287.41 | 3.52 | 3.52 |
| 301.43 | 3.86 | 3.86 |
| 160.18 | 1.52 | 1.52 |
| 410.28 | 4.87 | 4.87 |
| 401.42 | 4.04 | 4.04 |
| 466.83 | 4.29 | 4.29 |
| 430.39 | 3.74 | 3.74 |
| 355.42 | 3.87 | 3.87 |
| 401.44 | 3.58 | 3.58 |
| 386.39 | 3.47 | 3.47 |
| 356.40 | 3.15 | 3.15 |
| 354.43 | 3.75 | 3.75 |
| 400.46 | 3.46 | 3.46 |
| 409.29 | 4.75 | 4.75 |
| 467.33 | 4.78 | 4.78 |
| 412.47 | 3.78 | 3.78 |
| 443.44 | 3.38 | 3.38 |
| 413.46 | 3.06 | 3.06 |
| 289.32 | 0.59 | 0.59 |
| 174.20 | 1.83 | 1.83 |
| 193.17 | -1.63 | -1.63 |
| 507.02 | 5.00 | 5.00 |
| 336.32 | 3.15 | 3.15 |
| 175.19 | 1.83 | 1.83 |
| 298.34 | 2.85 | 2.85 |
| 421.49 | 3.83 | 3.83 |
| 344.37 | 3.74 | 3.74 |
| 432.55 | 5.60 | 5.60 |
| 159.19 | 2.13 | 2.13 |
| 377.96 | 5.31 | 5.31 |
| 355.42 | 3.02 | 3.02 |
| 324.34 | 3.45 | 3.45 |
| 293.34 | 2.50 | 2.50 |
| 404.36 | 2.86 | 2.86 |
| 255.23 | 1.46 | 1.46 |
| 190.16 | 1.85 | 1.85 |
| 264.31 | 1.78 | 1.78 |
| 318.33 | 2.88 | 2.88 |
| 293.80 | 3.44 | 3.44 |
| 373.54 | 3.94 | 3.94 |
| 283.29 | 0.52 | 0.52 |
| 347.37 | 2.34 | 2.34 |
| 257.32 | 3.33 | 3.33 |
| 260.34 | 2.32 | 2.32 |
| 353.41 | 3.09 | 3.09 |
| 343.34 | 2.75 | 2.75 |
| 587.53 | 8.36 | 8.36 |
| 355.42 | 3.02 | 3.02 |
| 285.32 | 3.59 | 3.59 |
| 509.41 | 6.51 | 6.51 |
| 487.41 | 6.60 | 6.60 |
| 478.57 | 5.31 | 5.31 |
| 323.40 | 1.87 | 1.87 |
| 160.18 | 1.52 | 1.52 |
| 160.22 | 2.37 | 2.37 |
| 385.40 | 3.35 | 3.35 |
| 385.40 | 3.35 | 3.35 |
| 294.29 | 2.10 | 2.10 |