Basic Information
ID: ALA1613949
Type: Functional
Description: PUBCHEM_BIOASSAY: HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target. Inhibition of phosphatase activity by colorimetric assay of released free phosphate (BioMol green). Secondary Screen (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1613949
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.22 | 1.57 | 1.57 |
| 142.11 | 0.40 | 0.40 |
| 277.80 | 3.64 | 3.64 |
| 215.25 | 2.79 | 2.79 |
| 444.44 | -0.21 | -0.21 |
| 243.31 | 2.97 | 2.97 |
| 418.43 | 0.59 | 0.59 |
| 306.32 | 1.89 | 1.89 |
| 222.27 | 2.23 | 2.23 |
| 337.43 | 1.19 | 1.19 |
| 331.30 | 0.01 | 0.01 |
| 334.46 | 4.06 | 4.06 |
| 383.83 | 2.44 | 2.44 |
| 364.37 | 1.20 | 1.20 |
| 304.35 | 2.89 | 2.89 |
| 310.40 | 2.14 | 2.14 |
| 386.86 | 1.61 | 1.61 |
| 375.43 | 2.11 | 2.11 |
| 319.37 | 3.19 | 3.19 |
| 373.85 | 1.67 | 1.67 |
| 299.33 | 2.43 | 2.43 |
| 353.42 | 3.20 | 3.20 |
| 409.45 | 3.54 | 3.54 |
| 212.27 | 1.49 | 1.49 |
| 442.57 | 3.50 | 3.50 |
| 354.32 | 1.79 | 1.79 |
| 287.30 | 2.16 | 2.16 |
| 375.45 | 2.13 | 2.13 |
| 355.40 | 4.10 | 4.10 |
| 388.42 | 4.78 | 4.78 |
| 287.32 | 2.40 | 2.40 |
| 341.41 | 3.71 | 3.71 |
| 286.29 | 2.20 | 2.20 |
| 312.76 | 3.98 | 3.98 |
| 372.46 | 4.00 | 4.00 |
| 210.66 | 2.85 | 2.85 |
| 409.27 | 2.71 | 2.71 |
| 355.85 | 4.24 | 4.24 |
| 343.40 | 2.60 | 2.60 |
| 355.42 | 3.04 | 3.04 |
| 470.34 | 5.98 | 5.98 |
| 295.43 | 3.51 | 3.51 |
| 319.32 | 3.67 | 3.67 |
| 209.20 | 0.11 | 0.11 |
| 484.50 | -0.23 | -0.23 |
| 402.45 | 1.74 | 1.74 |
| 324.38 | 3.18 | 3.18 |
| 232.31 | 1.89 | 1.89 |
| 425.54 | 2.94 | 2.94 |
| 320.41 | 2.53 | 2.53 |
| 414.53 | 4.24 | 4.24 |
| 468.29 | 3.57 | 3.57 |
| 377.31 | 4.25 | 4.25 |
| 476.49 | 2.63 | 2.63 |
| 229.28 | 2.53 | 2.53 |
| 370.43 | 3.36 | 3.36 |
| 453.92 | 3.02 | 3.02 |
| 344.33 | 5.52 | 5.52 |
| 395.50 | 3.04 | 3.04 |
| 295.19 | 2.49 | 2.49 |
| 226.28 | 3.16 | 3.16 |
| 345.38 | 2.99 | 2.99 |
| 315.37 | 5.11 | 5.11 |
| 285.30 | 2.48 | 2.48 |
| 337.31 | 3.81 | 3.81 |
| 173.27 | 1.40 | 1.40 |
| 208.17 | 0.25 | 0.25 |
| 364.41 | 3.76 | 3.76 |
| 265.77 | 3.18 | 3.18 |
| 394.93 | 3.55 | 3.55 |
| 420.49 | 1.84 | 1.84 |
| 385.49 | 2.73 | 2.73 |
| 392.55 | 4.44 | 4.44 |
| 283.28 | 2.55 | 2.55 |
| 465.56 | 3.91 | 3.91 |
| 386.79 | 2.65 | 2.65 |
| 345.45 | 3.38 | 3.38 |
| 318.45 | 1.79 | 1.79 |
| 364.37 | 3.03 | 3.03 |
| 243.31 | 2.84 | 2.84 |
| 274.29 | 2.62 | 2.62 |
| 360.43 | 3.22 | 3.22 |
| 443.98 | 3.45 | 3.45 |
| 335.39 | 4.68 | 4.68 |
| 292.31 | 1.38 | 1.38 |
| 410.48 | 4.81 | 4.81 |
| 455.89 | 4.86 | 4.86 |
| 215.25 | 2.16 | 2.16 |
| 411.46 | 2.31 | 2.31 |
| 305.43 | 2.65 | 2.65 |
| 160.22 | 2.40 | 2.40 |
| 307.37 | 2.84 | 2.84 |
| 324.43 | 2.53 | 2.53 |
| 288.30 | -0.34 | -0.34 |
| 338.39 | 3.18 | 3.18 |
| 483.55 | 2.26 | 2.26 |
| 461.52 | 2.09 | 2.09 |
| 388.31 | 2.99 | 2.99 |
| 374.51 | 3.42 | 3.42 |
| 281.26 | 2.57 | 2.57 |
| 262.31 | 1.19 | 1.19 |
| 251.37 | 2.43 | 2.43 |
| 405.51 | 3.14 | 3.14 |
| 406.44 | 1.23 | 1.23 |
| 461.58 | 2.35 | 2.35 |
| 336.41 | 2.32 | 2.32 |
| 308.37 | 3.36 | 3.36 |
| 406.54 | 3.65 | 3.65 |
| 390.30 | 4.89 | 4.89 |
| 271.34 | 2.83 | 2.83 |
| 350.42 | 3.53 | 3.53 |
| 262.33 | 3.08 | 3.08 |
| 375.38 | 4.32 | 4.32 |
| 175.19 | 1.00 | 1.00 |
| 431.45 | 2.29 | 2.29 |
| 481.53 | 1.93 | 1.93 |
| 311.36 | 1.42 | 1.42 |
| 269.28 | 2.40 | 2.40 |
| 445.54 | 2.55 | 2.55 |
| 460.49 | 4.96 | 4.96 |
| 231.25 | 1.93 | 1.93 |
| 355.38 | 1.91 | 1.91 |
| 245.28 | 2.23 | 2.23 |
| 221.26 | 3.14 | 3.14 |
| 421.53 | 3.51 | 3.51 |
| 345.42 | 2.51 | 2.51 |
| 314.18 | 2.66 | 2.66 |
| 374.32 | 5.22 | 5.22 |
| 477.45 | 2.53 | 2.53 |
| 367.88 | 2.19 | 2.19 |
| 204.19 | 0.45 | 0.45 |
| 349.44 | 2.81 | 2.81 |
| 229.28 | 3.10 | 3.10 |
| 316.34 | 2.90 | 2.90 |
| 271.34 | 1.19 | 1.19 |
| 399.45 | 4.90 | 4.90 |
| 288.30 | 2.89 | 2.89 |
| 484.37 | 6.29 | 6.29 |
| 358.81 | 4.75 | 4.75 |
| 451.49 | 4.30 | 4.30 |
| 359.39 | 4.22 | 4.22 |
| 399.53 | 2.07 | 2.07 |
| 362.35 | 2.43 | 2.43 |
| 222.33 | 2.26 | 2.26 |
| 323.40 | 1.87 | 1.87 |
| 272.34 | 1.05 | 1.05 |
| 292.34 | 3.25 | 3.25 |
| 470.33 | 2.78 | 2.78 |
| 469.97 | 2.06 | 2.06 |
| 307.26 | 3.83 | 3.83 |
| 440.25 | 5.02 | 5.02 |
| 479.54 | 3.16 | 3.16 |
| 322.39 | 0.93 | 0.93 |
| 404.25 | 2.73 | 2.73 |
| 328.42 | 3.15 | 3.15 |
| 230.22 | 1.98 | 1.98 |
| 307.31 | 3.41 | 3.41 |
| 359.48 | 3.32 | 3.32 |