Basic Information
ID: ALA1613953
Type: Functional
Description: PUBCHEM_BIOASSAY: Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Synthesized analogs 3. (Class of assay: confirmatory) [Related pubchem assays: 1796 (Summary AID (NOX1 inhibitors)), 2752 (Dose response (NOX1 inhibitors, synthesized analogs set 2)), 2532 (Dose response (NOX1 inhibitors, HEK/293 cells)), 2664 (Dose response (NOX1 inhibitors, synthesized analogs)), 1792 (Primary Screen (NOX1 inhibitors)), 2545 (Confirmation screen (NOX1 inhibitors, HEK/293 cells)), 2539 (Counterscreen (NOX2, NOX3, NOX4 inhibition)), 2556 (Dose response counterscreen (Xanthine Oxidase inhibitors)), 2538 (Dose response (NOX1 inhibitors)), 2541 (Confirmation screen (NOX1 inhibitors)), 1823 (Counterscreen (luminal))]
Format: BAO_0000219
Organism: Homo sapiens
Target: NADPH oxidase 1(ALA1287628)
Document: ALA1201862
PubChem Source: AID:2773
Activity Charts
Bioactivity
Activity Types for Assay ALA1613953
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.41 | 5.15 | 5.15 |
| 332.43 | 4.73 | 4.73 |
| 358.43 | 6.09 | 6.09 |
| 396.31 | 5.91 | 5.91 |
| 437.32 | 6.85 | 6.85 |